Targeted disruption of hoxc-4 causes esophageal defects and vertebral transformations
about
Familial syndromic esophageal atresia maps to 2p23-p24.VACTERL/VATER AssociationRegulation of aicda expression and AID activity: relevance to somatic hypermutation and class switch DNA recombinationHoxC4 binds to the promoter of the cytidine deaminase AID gene to induce AID expression, class-switch DNA recombination and somatic hypermutationOesophageal atresia, tracheo-oesophageal fistula, and the VACTERL association: review of genetics and epidemiologyThe HoxC4 homeodomain protein mediates activation of the immunoglobulin heavy chain 3' hs1,2 enhancer in human B cells. Relevance to class switch DNA recombinationSignaling by FGF4 and FGF8 is required for axial elongation of the mouse embryoNeural crest-derived defects in experimental esophageal atresiaHoxc13 mutant mice lack external hairIdentification of glial cell line-derived neurotrophic factor-regulated genes important for spermatogonial stem cell self-renewal in the ratRole of the homeodomain transcription factor Bapx1 in mouse distal stomach developmentLoss of Hoxa5 gene function in mice perturbs intestinal maturationEndothelial cells express a novel, tumor necrosis factor-alpha-regulated variant of HOXA9.Characterization of the chromosomal inversion associated with the Koa mutation in the mouse revealed the cause of skeletal abnormalitiesHomeobox genes in gut development.Vertebrate intestinal endoderm development.Establishment of intestinal identity and epithelial-mesenchymal signaling by Cdx2.RNA regulons in Hox 5' UTRs confer ribosome specificity to gene regulation.Rostral and caudal pharyngeal arches share a common neural crest ground patternEvidence for a functional role of epigenetically regulated midcluster HOXB genes in the development of Barrett esophagusGenetic and cellular mechanisms regulating anterior foregut and esophageal development.Hox genes regulate the onset of Tbx5 expression in the forelimb.Hoxc8 initiates an ectopic mammary program by regulating Fgf10 and Tbx3 expression and Wnt/β-catenin signalingAdriamycin-Induced Models of VACTERL Association.Embryology of oesophageal atresia.Signaling by small GTPases in the immune system.Partial functional redundancy between Hoxa5 and Hoxb5 paralog genes during lung morphogenesis.Molecular basis for skeletal variation: insights from developmental genetic studies in mice.Axial and appendicular skeletal transformations, ligament alterations, and motor neuron loss in Hoxc10 mutants.A conserved role for Hox paralog group 4 in regulation of hematopoietic progenitors.Boundaries, junctions and transitions in the gastrointestinal tract.The initial establishment and epithelial morphogenesis of the esophagus: a new model of tracheal-esophageal separation and transition of simple columnar into stratified squamous epithelium in the developing esophagus.Reduced proliferative capacity of hematopoietic stem cells deficient in Hoxb3 and Hoxb4.Characterization and retinoic acid responsiveness of the murine Hoxd4 transcription unit.Crypto-rhombomeres of the mouse medulla oblongata, defined by molecular and morphological features.Region-specific expression of murine Hox genes implies the Hox code-mediated patterning of the digestive tract.
P2860
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P2860
Targeted disruption of hoxc-4 causes esophageal defects and vertebral transformations
description
1996 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1996
@ast
im Juli 1996 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1996/07/10)
@sk
vědecký článek publikovaný v roce 1996
@cs
wetenschappelijk artikel (gepubliceerd op 1996/07/10)
@nl
наукова стаття, опублікована в липні 1996
@uk
مقالة علمية (نشرت في 10-7-1996)
@ar
name
Targeted disruption of hoxc-4 causes esophageal defects and vertebral transformations
@ast
Targeted disruption of hoxc-4 causes esophageal defects and vertebral transformations
@en
Targeted disruption of hoxc-4 causes esophageal defects and vertebral transformations
@nl
type
label
Targeted disruption of hoxc-4 causes esophageal defects and vertebral transformations
@ast
Targeted disruption of hoxc-4 causes esophageal defects and vertebral transformations
@en
Targeted disruption of hoxc-4 causes esophageal defects and vertebral transformations
@nl
prefLabel
Targeted disruption of hoxc-4 causes esophageal defects and vertebral transformations
@ast
Targeted disruption of hoxc-4 causes esophageal defects and vertebral transformations
@en
Targeted disruption of hoxc-4 causes esophageal defects and vertebral transformations
@nl
P356
P1476
Targeted disruption of hoxc-4 causes esophageal defects and vertebral transformations
@en
P2093
A. M. Boulet
M. R. Capecchi
P304
P356
10.1006/DBIO.1996.0159
P407
P577
1996-07-10T00:00:00Z