The MAPK-activated kinase Rsk controls an acute Toll-like receptor signaling response in dendritic cells and is activated through two distinct pathways
about
Activation and function of the MAPKs and their substrates, the MAPK-activated protein kinasesThe selectivity of protein kinase inhibitors: a further updateMAPK-Activated Protein Kinases (MKs): Novel Insights and ChallengesInsights into phagocytosis-coupled activation of pattern recognition receptors and inflammasomesMutation of the PDK1 PH Domain Inhibits Protein Kinase B/Akt, Leading to Small Size and Insulin ResistanceCD14 controls the LPS-induced endocytosis of Toll-like receptor 4Salmeterol attenuates the inflammatory response in asthma and decreases the pro-inflammatory cytokine secretion of dendritic cells.Toll-like receptor signaling in cell proliferation and survivalMolecular control of steady-state dendritic cell maturation and immune homeostasis.TNF and MAP kinase signalling pathways.Nuclear BK channels regulate gene expression via the control of nuclear calcium signaling.Outer membrane protein a of Salmonella enterica serovar Typhimurium activates dendritic cells and enhances Th1 polarizationIL-3 Maintains Activation of the p90S6K/RPS6 Pathway and Increases Translation in Human EosinophilsStructural and functional basis for p38-MK2-activated Rsk signaling in toll-like receptor-stimulated dendritic cells.Novel function for the p38-MK2 signaling pathway in circulating CD1c+ (BDCA-1+) myeloid dendritic cells from healthy donors and advanced cancer patients; inhibition of p38 enhances IL-12 whilst suppressing IL-10.Alcohol intoxication following muscle contraction in mice decreases muscle protein synthesis but not mTOR signal transduction.Label-Free Protein-RNA Interactome Analysis Identifies Khsrp Signaling Downstream of the p38/Mk2 Kinase Complex as a Critical Modulator of Cell Cycle Progression.The PDK1-Rsk Signaling Pathway Controls Langerhans Cell Proliferation and Patterning.Epidermal growth factor (EGF) regulates α5β1 integrin activation state in human cancer cell lines through the p90RSK-dependent phosphorylation of filamin AStructural Basis of Ribosomal S6 Kinase 1 (RSK1) Inhibition by S100B Protein: MODULATION OF THE EXTRACELLULAR SIGNAL-REGULATED KINASE (ERK) SIGNALING CASCADE IN A CALCIUM-DEPENDENT WAY.Apigenin, a potent suppressor of dendritic cell maturation and migration, protects against collagen-induced arthritisProstaglandins from Cytosolic Phospholipase A2α/Cyclooxygenase-1 Pathway and Mitogen-activated Protein Kinases Regulate Gene Expression in Candida albicans-infected Macrophages.The kinase p38 alpha serves cell type-specific inflammatory functions in skin injury and coordinates pro- and anti-inflammatory gene expressionActivation of pattern recognition receptor-mediated innate immunity inhibits the replication of hepatitis B virus in human hepatocyte-derived cellsCross talk between the Akt and p38α pathways in macrophages downstream of Toll-like receptor signaling.Lipoprotein accumulation in macrophages via toll-like receptor-4-dependent fluid phase uptake.Regulation of JNK and p38 MAPK in the immune system: signal integration, propagation and termination.Loss of Functionally Redundant p38 Isoforms in T Cells Enhances Regulatory T Cell InductionFibroblast growth factor signalling induces loss of progesterone receptor in breast cancer cells.Targeting RSK2 in human malignancies.Cyclic di-nucleotides: new era for small molecules as adjuvants.Mammalian MAPK signal transduction pathways activated by stress and inflammation: a 10-year update.Phagosome as the organelle linking innate and adaptive immunity.Ribosomal S6 kinase (RSK) modulators: a patent review.A dominant mutation in MAPKAPK3, an actor of p38 signaling pathway, causes a new retinal dystrophy involving Bruch's membrane and retinal pigment epithelium.The p90 ribosomal S6 kinase (RSK) inhibitor BI-D1870 prevents gamma irradiation-induced apoptosis and mediates senescence via RSK- and p53-independent accumulation of p21WAF1/CIP1.PDK1 regulates VDJ recombination, cell-cycle exit and survival during B-cell developmentCD13 regulates dendritic cell cross-presentation and T cell responses by inhibiting receptor-mediated antigen uptakeThe Role of Mitogen-Activated Protein Kinase-Activated Protein Kinases (MAPKAPKs) in Inflammation.A combination of SILAC and nucleotide acyl phosphate labelling reveals unexpected targets of the Rsk inhibitor BI-D1870.
P2860
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P248
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P2860
The MAPK-activated kinase Rsk controls an acute Toll-like receptor signaling response in dendritic cells and is activated through two distinct pathways
description
2007 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2007
@ast
im November 2007 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2007/11/01)
@sk
vědecký článek publikovaný v roce 2007
@cs
wetenschappelijk artikel (gepubliceerd op 2007/11/01)
@nl
наукова стаття, опублікована в листопаді 2007
@uk
مقالة علمية (نشرت في نوفمبر 2007)
@ar
name
The MAPK-activated kinase Rsk ...... through two distinct pathways
@ast
The MAPK-activated kinase Rsk ...... through two distinct pathways
@en
The MAPK-activated kinase Rsk ...... through two distinct pathways
@nl
type
label
The MAPK-activated kinase Rsk ...... through two distinct pathways
@ast
The MAPK-activated kinase Rsk ...... through two distinct pathways
@en
The MAPK-activated kinase Rsk ...... through two distinct pathways
@nl
prefLabel
The MAPK-activated kinase Rsk ...... through two distinct pathways
@ast
The MAPK-activated kinase Rsk ...... through two distinct pathways
@en
The MAPK-activated kinase Rsk ...... through two distinct pathways
@nl
P50
P921
P356
P1433
P1476
The MAPK-activated kinase Rsk ...... through two distinct pathways
@en
P2093
J. Simon C. Arthur
P304
P356
10.1038/NI1517
P407
P577
2007-11-01T00:00:00Z