Impaired NMDA receptor-mediated postsynaptic function and blunted NMDA receptor-dependent persistent pain in mice lacking postsynaptic density-93 protein
about
Discs-large (DLG) is clustered by presynaptic innervation and regulates postsynaptic glutamate receptor subunit composition in DrosophilaDisrupting 5-HT(2A) receptor/PDZ protein interactions reduces hyperalgesia and enhances SSRI efficacy in neuropathic painSleep deprivation-induced alterations in excitatory synaptic transmission in the CA1 region of the rat hippocampusPostsynaptic assembly induced by neurexin-neuroligin interaction and neurotransmitter.Spinal cord protein interacting with C kinase 1 is required for the maintenance of complete Freund's adjuvant-induced inflammatory pain but not for incision-induced post-operative pain.Stress induces pain transition by potentiation of AMPA receptor phosphorylation.Experimental validation of the regulated expression of large numbers of non-coding RNAs from the mouse genomePreserved acute pain and impaired neuropathic pain in mice lacking protein interacting with C Kinase 1Effect of inhibition of spinal cord glutamate transporters on inflammatory pain induced by formalin and complete Freund's adjuvantNerve injury-induced epigenetic silencing of opioid receptors controlled by DNMT3a in primary afferent neurons.Inflammation alters trafficking of extrasynaptic AMPA receptors in tonically firing lamina II neurons of the rat spinal dorsal horn.Genetic knockout and pharmacologic inhibition of neuronal nitric oxide synthase attenuate nerve injury-induced mechanical hypersensitivity in mice.TNFalpha-induced AMPA-receptor trafficking in CNS neurons; relevance to excitotoxicity?Distinct expression of synaptic NR2A and NR2B in the central nervous system and impaired morphine tolerance and physical dependence in mice deficient in postsynaptic density-93 protein.Dorsal root ganglion transcriptome analysis following peripheral nerve injury in mice.Persistent inflammation induces GluR2 internalization via NMDA receptor-triggered PKC activation in dorsal horn neurons.Differential roles of postsynaptic density-93 isoforms in regulating synaptic transmission.PDZ domains at excitatory synapses: potential molecular targets for persistent pain treatment.Post-synaptic density-93 mediates tyrosine-phosphorylation of the N-methyl-D-aspartate receptors.Involvement of Brain-Enriched Guanylate Kinase-Associated Protein (BEGAIN) in Chronic Pain after Peripheral Nerve Injury.Central sensitization: a generator of pain hypersensitivity by central neural plasticity.Proteome of synaptosome-associated proteins in spinal cord dorsal horn after peripheral nerve injury.Neuropathic pain: a maladaptive response of the nervous system to damage.G9a participates in nerve injury-induced Kcna2 downregulation in primary sensory neurons.G9a inhibits CREB-triggered expression of mu opioid receptor in primary sensory neurons following peripheral nerve injury.Inhibition of the regulator of G protein signalling RGS4 in the spinal cord decreases neuropathic hyperalgesia and restores cannabinoid CB1 receptor signalling.DNA methyltransferase DNMT3a contributes to neuropathic pain by repressing Kcna2 in primary afferent neurons.Electrophysiological characterization of spinal neuron sensitization by elevated calcium channel alpha-2-delta-1 subunit protein.[EXPRESS] Role of dorsal root ganglion K2p1.1 in peripheral nerve injury-induced neuropathic pain.Glutamate receptor phosphorylation and trafficking in pain plasticity in spinal cord dorsal horn.Perturbing PSD-95 interactions with NR2B-subtype receptors attenuates spinal nociceptive plasticity and neuropathic pain.Aplysia synapse associated protein (APSAP): identification, characterization, and selective interactions with Shaker-type potassium channels.The transcription factor C/EBPβ in the dorsal root ganglion contributes to peripheral nerve trauma-induced nociceptive hypersensitivity.[EXPRESS] DNMT3a contributes to the development and maintenance of bone cancer pain by silencing Kv1.2 expression in spinal cord dorsal horn.The synergistic effect of treatment with triptolide and MK-801 in the rat neuropathic pain model.Calcium-permeable AMPA receptors and silent synapses in cocaine-conditioned place preference.
P2860
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P2860
Impaired NMDA receptor-mediated postsynaptic function and blunted NMDA receptor-dependent persistent pain in mice lacking postsynaptic density-93 protein
description
2003 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2003
@ast
im Juli 2003 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2003/07/30)
@sk
vědecký článek publikovaný v roce 2003
@cs
wetenschappelijk artikel (gepubliceerd op 2003/07/30)
@nl
наукова стаття, опублікована в липні 2003
@uk
مقالة علمية (نشرت في 30-7-2003)
@ar
name
Impaired NMDA receptor-mediate ...... ostsynaptic density-93 protein
@ast
Impaired NMDA receptor-mediate ...... ostsynaptic density-93 protein
@en
Impaired NMDA receptor-mediate ...... ostsynaptic density-93 protein
@nl
type
label
Impaired NMDA receptor-mediate ...... ostsynaptic density-93 protein
@ast
Impaired NMDA receptor-mediate ...... ostsynaptic density-93 protein
@en
Impaired NMDA receptor-mediate ...... ostsynaptic density-93 protein
@nl
prefLabel
Impaired NMDA receptor-mediate ...... ostsynaptic density-93 protein
@ast
Impaired NMDA receptor-mediate ...... ostsynaptic density-93 protein
@en
Impaired NMDA receptor-mediate ...... ostsynaptic density-93 protein
@nl
P2093
P921
P3181
P1476
Impaired NMDA receptor-mediate ...... ostsynaptic density-93 protein
@en
P2093
Chengshui Zhao
David S. Bredt
Frederick W. Kauer
Gavin Rumbaugh
Guo-Du Wang
Richard L. Huganir
Robert J. Wenthold
Roger A. Johns
P304
P3181
P356
10.1016/J.JPAIN.2005.01.025
P407
P577
2003-07-30T00:00:00Z