Progenitor cell maintenance requires numb and numblike during mouse neurogenesis
about
Identification and selected reaction monitoring (SRM) quantification of endocytosis factors associated with NumbRole of numb in dendritic spine development with a Cdc42 GEF intersectin and EphB2.The TRIM-NHL protein TRIM32 activates microRNAs and prevents self-renewal in mouse neural progenitorsEph/ephrin molecules--a hub for signaling and endocytosisEpigenetic regulation of miR-184 by MBD1 governs neural stem cell proliferation and differentiationNumb links extracellular cues to intracellular polarity machinery to promote chemotaxisSignaling mechanisms regulating adult neural stem cells and neurogenesisImpaired maturation of dendritic spines without disorganization of cortical cell layers in mice lacking NRG1/ErbB signaling in the central nervous systemPlacental expression of estrogen receptor beta and its hormone binding variant--comparison with estrogen receptor alpha and a role for estrogen receptors in asymmetric division and differentiation of estrogen-dependent cellsNeuroplasticity and Repair in Rodent Neurotoxic Models of Spinal Motoneuron DiseaseMolecular mechanisms controlling asymmetric and symmetric self-renewal of cancer stem cellsTissue-specific stem cells: lessons from the skeletal muscle satellite cellExtensions of MADM (mosaic analysis with double markers) in miceExcessive vascular sprouting underlies cerebral hemorrhage in mice lacking αVβ8-TGFβ signaling in the brain.Persistent expression of stabilized beta-catenin delays maturation of radial glial cells into intermediate progenitorsPostnatal deletion of Numb/Numblike reveals repair and remodeling capacity in the subventricular neurogenic nichePhosphorylation of Numb regulates its interaction with the clathrin-associated adaptor AP-2Loss of cell polarity causes severe brain dysplasia in Lgl1 knockout miceGenome-wide analysis of N1ICD/RBPJ targets in vivo reveals direct transcriptional regulation of Wnt, SHH, and hippo pathway effectors by Notch1NRP1 acts cell autonomously in endothelium to promote tip cell function during sprouting angiogenesisVascular development of the brain requires beta8 integrin expression in the neuroepitheliumVEGF signalling controls GnRH neuron survival via NRP1 independently of KDR and blood vesselsEya1 controls cell polarity, spindle orientation, cell fate and Notch signaling in distal embryonic lung epitheliumTargeted deletion of numb and numblike in sensory neurons reveals their essential functions in axon arborizationNetwork analysis of microRNA and mRNA seasonal dynamics in a highly plastic sensorimotor neural circuitGrowth and folding of the mammalian cerebral cortex: from molecules to malformationsNumb deficiency in cerebellar Purkinje cells impairs synaptic expression of metabotropic glutamate receptor and motor coordination.The apical complex couples cell fate and cell survival to cerebral cortical development.Epicardial spindle orientation controls cell entry into the myocardiumTissue macrophages act as cellular chaperones for vascular anastomosis downstream of VEGF-mediated endothelial tip cell induction.Numb family proteins are essential for cardiac morphogenesis and progenitor differentiationNumb is not a critical regulator of Notch-mediated cell fate decisions in the developing chick inner ear.Precardiac deletion of Numb and Numblike reveals renewal of cardiac progenitorsVisualizing the distribution of synapses from individual neurons in the mouse brain.Protein kinase C-alpha suppresses autophagy and induces neural tube defects via miR-129-2 in diabetic pregnancy.The transition from radial glial to intermediate progenitor cell is inhibited by FGF signaling during corticogenesis.A recurrent mutation in bone morphogenetic proteins-2-inducible kinase gene is associated with developmental dysplasia of the hip.Numb proteins specify asymmetric cell fates via an endocytosis- and proteasome-independent pathway.p600 regulates spindle orientation in apical neural progenitors and contributes to neurogenesis in the developing neocortex.Prox1 regulates the notch1-mediated inhibition of neurogenesis.
P2860
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P2860
Progenitor cell maintenance requires numb and numblike during mouse neurogenesis
description
2002 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Nature
@fr
artículu científicu espublizáu en 2002
@ast
scientific journal article
@en
vedecký článok (publikovaný 2002/10/31)
@sk
vědecký článek publikovaný v roce 2002
@cs
wetenschappelijk artikel (gepubliceerd op 2002/10/31)
@nl
наукова стаття, опублікована в жовтні 2002
@uk
مقالة علمية (نشرت في 31-10-2002)
@ar
name
Progenitor cell maintenance requires numb and numblike during mouse neurogenesis
@ast
Progenitor cell maintenance requires numb and numblike during mouse neurogenesis
@en
Progenitor cell maintenance requires numb and numblike during mouse neurogenesis
@nl
type
label
Progenitor cell maintenance requires numb and numblike during mouse neurogenesis
@ast
Progenitor cell maintenance requires numb and numblike during mouse neurogenesis
@en
Progenitor cell maintenance requires numb and numblike during mouse neurogenesis
@nl
prefLabel
Progenitor cell maintenance requires numb and numblike during mouse neurogenesis
@ast
Progenitor cell maintenance requires numb and numblike during mouse neurogenesis
@en
Progenitor cell maintenance requires numb and numblike during mouse neurogenesis
@nl
P2093
P2860
P3181
P356
P1433
P1476
Progenitor cell maintenance requires numb and numblike during mouse neurogenesis
@en
P2093
Joseph K. Hwang
Kaiyong Zou
Petur H. Petersen
Weimin Zhong
P2860
P2888
P304
P3181
P356
10.1038/NATURE01124
P407
P50
P577
2002-10-31T00:00:00Z
P6179
1040723686