CaV2.3 calcium channels control second-phase insulin release
about
Oscillations, intercellular coupling, and insulin secretion in pancreatic beta cells.The mitochondrial Na+/Ca2+ exchanger upregulates glucose dependent Ca2+ signalling linked to insulin secretionThe Physiology, Pathology, and Pharmacology of Voltage-Gated Calcium Channels and Their Future Therapeutic PotentialAlpha-, Delta- and PP-cells: Are They the Architectural Cornerstones of Islet Structure and Co-ordination?Characterization of voltage-dependent sodium and calcium channels in mouse pancreatic A- and B-cells.Unifying concepts in stimulus-secretion coupling in endocrine cells and some implications for therapeutics.CACNA1E variants affect beta cell function in patients with newly diagnosed type 2 diabetes. the Verona newly diagnosed type 2 diabetes study (VNDS) 3Eukaryotic translation initiation factor 3 subunit e controls intracellular calcium homeostasis by regulation of cav1.2 surface expressionPlasma membrane potential oscillations in insulin secreting Ins-1 832/13 cells do not require glycolysis and are not initiated by fluctuations in mitochondrial bioenergetics.A dominant mutation in Snap25 causes impaired vesicle trafficking, sensorimotor gating, and ataxia in the blind-drunk mouse.CaV2.3 channel and PKClambda: new players in insulin secretionGlucose-induced electrical activities and insulin secretion in pancreatic islet β-cells are modulated by CFTRContribution of protein kinase Cα in the stimulation of insulin by the down-regulation of Cavβ subunits.IA-2beta, but not IA-2, is induced by ghrelin and inhibits glucose-stimulated insulin secretion.Mice deficient in GEM GTPase show abnormal glucose homeostasis due to defects in beta-cell calcium handlingFunctional properties of a newly identified C-terminal splice variant of Cav1.3 L-type Ca2+ channelsCoupling of metabolic, second messenger pathways and insulin granule dynamics in pancreatic beta-cells: a computational analysisHyperinsulinism and diabetes: genetic dissection of beta cell metabolism-excitation coupling in miceFTO Inhibits Insulin Secretion and Promotes NF-κB Activation through Positively Regulating ROS Production in Pancreatic β cells.FSH stimulates ovarian cancer cell growth by action on growth factor variant receptorSyntaxin-3 Binds and Regulates Both R- and L-Type Calcium Channels in Insulin-Secreting INS-1 832/13 Cells.Rfx6 maintains the functional identity of adult pancreatic β cells.Conotoxins that confer therapeutic possibilities.Optogenetic control of insulin secretion in intact pancreatic islets with β-cell-specific expression of Channelrhodopsin-2.Vitamin D supplementation as an adjuvant therapy for patients with T2DM: an 18-month prospective interventional study.Glucose-sensing mechanisms in pancreatic beta-cells.Identifying the targets of the amplifying pathway for insulin secretion in pancreatic beta-cells by kinetic modeling of granule exocytosis.Newcomer insulin secretory granules as a highly calcium-sensitive poolRegulation of insulin synthesis and secretion and pancreatic Beta-cell dysfunction in diabetes.Synaptotagmin-7 Functions to Replenish Insulin Granules for Exocytosis in Human Islet β-Cells.Regulation of calcium in pancreatic α- and β-cells in health and disease.Modes of exocytosis and electrogenesis underlying canine biphasic insulin secretion.Review: Cav2.3 R-type Voltage-Gated Ca2+ Channels - Functional Implications in Convulsive and Non-convulsive Seizure Activity.Exocyst sec5 regulates exocytosis of newcomer insulin granules underlying biphasic insulin secretion.How "Pharmacoresistant" is Cav2.3, the Major Component of Voltage-Gated R-type Ca2+ Channels?The triggering pathway to insulin secretion: Functional similarities and differences between the human and the mouse β cells and their translational relevance.Molecular mechanisms involved in the non-monotonic effect of bisphenol-a on ca2+ entry in mouse pancreatic β-cells.Aldehyde dehydrogenase activity is necessary for beta cell development and functionality in mice.Role of reduced β-cell mass versus impaired β-cell function in the pathogenesis of type 2 diabetes.BK channels mediate a novel ionic mechanism that regulates glucose-dependent electrical activity and insulin secretion in mouse pancreatic β-cells.
P2860
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P2860
CaV2.3 calcium channels control second-phase insulin release
description
2005 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2005
@ast
im Januar 2005 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2005/01/01)
@sk
vědecký článek publikovaný v roce 2005
@cs
wetenschappelijk artikel (gepubliceerd op 2005/01/01)
@nl
наукова стаття, опублікована в січні 2005
@uk
مقالة علمية (نشرت عام 2005)
@ar
name
CaV2.3 calcium channels control second-phase insulin release
@ast
CaV2.3 calcium channels control second-phase insulin release
@en
CaV2.3 calcium channels control second-phase insulin release
@nl
type
label
CaV2.3 calcium channels control second-phase insulin release
@ast
CaV2.3 calcium channels control second-phase insulin release
@en
CaV2.3 calcium channels control second-phase insulin release
@nl
prefLabel
CaV2.3 calcium channels control second-phase insulin release
@ast
CaV2.3 calcium channels control second-phase insulin release
@en
CaV2.3 calcium channels control second-phase insulin release
@nl
P2093
P2860
P3181
P356
P1476
CaV2.3 calcium channels control second-phase insulin release
@en
P2093
Alexey Pereverzev
Charlotta S. Olofsson
Dai-Qing Li
Erik Renström
Ingmar Lundquist
José Caballero
Rosita Ivarsson
Toni Schneider
Vikas V. Surve
Xingjun Jing
P2860
P304
P3181
P356
10.1172/JCI22518
P407
P577
2005-01-01T00:00:00Z