Activation of the ATR kinase by the RPA-binding protein ETAA1
about
ETAA1 acts at stalled replication forks to maintain genome integrityThe essential kinase ATR: ensuring faithful duplication of a challenging genome.Impact of Age and Insulin-Like Growth Factor-1 on DNA Damage Responses in UV-Irradiated Human Skin.Activating ATR, the devil's in the dETAA1l.S-phase checkpoint regulations that preserve replication and chromosome integrity upon dNTP depletion.Systems-guided forward genetic screen reveals a critical role of the replication stress response protein ETAA1 in T cell clonal expansion.A phosphorylation-and-ubiquitylation circuitry driving ATR activation and homologous recombination.Mutations in DONSON disrupt replication fork stability and cause microcephalic dwarfismRADX Promotes Genome Stability and Modulates Chemosensitivity by Regulating RAD51 at Replication Forks.RADX interacts with single-stranded DNA to promote replication fork stability.Proteomics reveals a new DNA repair factor involved in DNA damage signaling.Epstein-Barr Virus Hijacks DNA Damage Response Transducers to Orchestrate Its Life Cycle.Protoparvovirus Interactions with the Cellular DNA Damage Response.Around and beyond 53BP1 Nuclear Bodies.PIDD mediates the association of DNA-PKcs and ATR at stalled replication forks to facilitate the ATR signaling pathway.Cryo-EM structure of human ATR-ATRIP complex.Mouse embryonic stem cells have increased capacity for replication fork restart driven by the specific Filia-Floped protein complex.DNA damage response protein TOPBP1 regulates X chromosome silencing in the mammalian germ line.Functions of SMARCAL1, ZRANB3, and HLTF in maintaining genome stability.HELLS and CDCA7 comprise a bipartite nucleosome remodeling complex defective in ICF syndrome.Challenges to DNA replication in hypoxic conditions.Mechanisms of Oncogene-Induced Replication Stress: Jigsaw Falling into Place.The ATR-Activation Domain of TopBP1 Is Required for the Suppression of Origin Firing during the S PhaseUbiquitylation at the Fork: Making and Breaking Chains to Complete DNA ReplicationRecruitment of ubiquitin-activating enzyme UBA1 to DNA by poly(ADP-ribose) promotes ATR signalling
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Activation of the ATR kinase by the RPA-binding protein ETAA1
description
2016 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2016 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2016
@ast
im November 2016 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
@en
vedecký článok (publikovaný 2016/11/01)
@sk
vědecký článek publikovaný v roce 2016
@cs
wetenschappelijk artikel (gepubliceerd op 2016/11/01)
@nl
наукова стаття, опублікована в листопаді 2016
@uk
مقالة علمية (نشرت في نوفمبر 2016)
@ar
name
Activation of the ATR kinase by the RPA-binding protein ETAA1
@ast
Activation of the ATR kinase by the RPA-binding protein ETAA1
@en
Activation of the ATR kinase by the RPA-binding protein ETAA1
@nl
type
label
Activation of the ATR kinase by the RPA-binding protein ETAA1
@ast
Activation of the ATR kinase by the RPA-binding protein ETAA1
@en
Activation of the ATR kinase by the RPA-binding protein ETAA1
@nl
prefLabel
Activation of the ATR kinase by the RPA-binding protein ETAA1
@ast
Activation of the ATR kinase by the RPA-binding protein ETAA1
@en
Activation of the ATR kinase by the RPA-binding protein ETAA1
@nl
P2093
P2860
P50
P921
P356
P1433
P1476
Activation of the ATR kinase by the RPA-binding protein ETAA1
@en
P2093
Matthias Mann
Simon Bekker-Jensen
P2860
P2888
P304
P356
10.1038/NCB3422
P577
2016-11-01T00:00:00Z
P6179
1000558792