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The protooncogene Ski controls Schwann cell proliferation and myelinationNeural crest-derived cells with stem cell features can be traced back to multiple lineages in the adult skinA dual role for SOX10 in the maintenance of the postnatal melanocyte lineage and the differentiation of melanocyte stem cell progenitorsHuman CD271-positive melanoma stem cells associated with metastasis establish tumor heterogeneity and long-term growthNotch signalling controls pancreatic cell differentiationPramel7 mediates LIF/STAT3-dependent self-renewal in embryonic stem cellsNeuronal Nogo-A regulates neurite fasciculation, branching and extension in the developing nervous systemThe role of the Ets domain transcription factor Erm in modulating differentiation of neural crest stem cellsThe cellular function of MASH1 in autonomic neurogenesisTumor cell plasticity and angiogenesis in human melanomasWild-type ALK and activating ALK-R1275Q and ALK-F1174L mutations upregulate Myc and initiate tumor formation in murine neural crest progenitor cellsContext-dependent regulation of fate decisions in multipotent progenitor cells of the peripheral nervous system.In vivo tumorigenesis was observed after injection of in vitro expanded neural crest stem cells isolated from adult bone marrowThe epigenetic modifier EZH2 controls melanoma growth and metastasis through silencing of distinct tumour suppressors.Antagonistic cross-regulation between Sox9 and Sox10 controls an anti-tumorigenic program in melanoma.Open questions: development of tumor cell heterogeneity and its implications for cancer treatment.Methylation-dependent SOX9 expression mediates invasion in human melanoma cells and is a negative prognostic factor in advanced melanomaDistinct adhesion-independent functions of β-catenin control stage-specific sensory neurogenesis and proliferationLoss of Ezh2 promotes a midbrain-to-forebrain identity switch by direct gene derepression and Wnt-dependent regulationDiGeorge syndrome and pharyngeal apparatus development.Coexpression of SOX10/CD271 (p75(NTR)) and β-Galactosidase in Large to Giant Congenital Melanocytic Nevi of Pediatric Patients.Growth factors regulating neural crest cell fate decisions.The neural crest: understanding stem cell function in development and disease.Chemokines in neuroectodermal development and their potential implication in cancer stem cell-driven metastasis.Stage- and area-specific control of stem cells in the developing nervous system.Generation of melanocytes from neural crest cells.Testing the cancer stem cell hypothesis in melanoma: the clinics will tell.Sox10 promotes the formation and maintenance of giant congenital naevi and melanoma.Transforming growth factor β-mediated Sox10 suppression controls mesenchymal progenitor generation in neural crest stem cells.Quo vadis: tracing the fate of neural crest cells.Membrane-bound neuregulin1 type III actively promotes Schwann cell differentiation of multipotent Progenitor cells.Evidence of renal angiomyolipoma neoplastic stem cells arising from renal epithelial cells.low neurotrophin receptor CD271 regulates phenotype switching in melanoma.Multiple lineage-specific roles of Smad4 during neural crest development.Rare, yet relevant tumor cells - A new twist to melanoma cell plasticity.Publisher Correction: The low affinity neurotrophin receptor CD271 regulates phenotype switching in melanoma.Wnt/β-catenin signaling regulates sequential fate decisions of murine cortical precursor cells.Injury-activated glial cells promote wound healing of the adult skin in mice.Persistent Wnt/β-catenin signaling determines dorsalization of the postnatal subventricular zone and neural stem cell specification into oligodendrocytes and glutamatergic neurons.Premigratory and migratory neural crest cells are multipotent in vivo.
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P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Lukas Sommer
@ast
Lukas Sommer
@en
Lukas Sommer
@es
Lukas Sommer
@nl
Lukas Sommer
@sl
type
label
Lukas Sommer
@ast
Lukas Sommer
@en
Lukas Sommer
@es
Lukas Sommer
@nl
Lukas Sommer
@sl
prefLabel
Lukas Sommer
@ast
Lukas Sommer
@en
Lukas Sommer
@es
Lukas Sommer
@nl
Lukas Sommer
@sl
P106
P21
P31
P496
0000-0002-1143-7908