Mechanism of action of factor D of the alternative complement pathway
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Production and interferon-gamma-mediated regulation of complement component C2 and factors B and D by the astroglioma cell line U105-MGStructural basis of profactor D activation: from a highly flexible zymogen to a novel self-inhibited serine protease, complement factor DInhibiting Alternative Pathway Complement Activation by Targeting the Factor D ExositeCrystal structure of a complement factor D mutant expressing enhanced catalytic activityThe complement system: an evolution in progressFormation of the initial C3 convertase of the alternative complement pathway. Acquisition of C3b-like activities by spontaneous hydrolysis of the putative thioester in native C3Mutations of factor H impair regulation of surface-bound C3b by three mechanisms in atypical hemolytic uremic syndrome.Human complement protein D catabolism by the rat kidney.Essential role of complement mannose-binding lectin-associated serine proteases-1/3 in the murine collagen antibody-induced model of inflammatory arthritis.Complement factor D in age-related macular degenerationManduca sexta hemolymph proteinase 21 activates prophenoloxidase-activating proteinase 3 in an insect innate immune response proteinase cascade.Small-molecule factor D inhibitors targeting the alternative complement pathway.Lutein Leads to a Decrease of Factor D Secretion by Cultured Mature Human Adipocytes.Release of soluble immune complexes from immune adherence receptors on human erythrocytes is mediated by C3b inactivator independently of Beta 1H and is accompanied by generation of C3c.Factor B, the complement alternative pathway serine proteinase, is a major constitutive protein synthesized and secreted by resident and elicited mouse macrophages.Growth-supporting activity of fragment Ba of the human alternative complement pathway for activated murine B lymphocytesAntibody-independent activation of the alternative complement pathway by measles virus-infected cellsPartial amino acid sequence of human factor D:homology with serine proteases.Induction of immune cytolysis: tumor-cell killing by complement is initiated by covalent complex of monoclonal antibody and stable C3/C5 convertase.Active site amino acid sequence of human factor D.Properdin factor D: effects on thrombin-induced platelet aggregation.MASP-3 is the exclusive pro-factor D activator in resting blood: the lectin and the alternative complement pathways are fundamentally linkedC3 dysregulation due to factor H deficiency is mannan-binding lectin-associated serine proteases (MASP)-1 and MASP-3 independent in vivo.Genetic susceptibility to meningococcal infection.Adipsin and complement factor D activity: an immune-related defect in obesity.The emerging roles of mannose-binding lectin-associated serine proteases (MASPs) in the lectin pathway of complement and beyond.THE PATHOPHYSIOLOGY OF GEOGRAPHIC ATROPHY SECONDARY TO AGE-RELATED MACULAR DEGENERATION AND THE COMPLEMENT PATHWAY AS A THERAPEUTIC TARGET.Role of fibrinogen in complement inhibition by streptococcal M protein.Activation of the alternative and classical complement pathways by Entamoeba histolytica.Physiology and pathophysiology of complement: progress and trends.Complete and partial deficiencies of complement factor D in a Dutch family.Complement factor D-like activity of Porphyromonas gingivalis W83.The C3 convertase of the alternative pathway of human complement. Enzymic properties of the bimolecular proteinase.Factor D of the alternative pathway of human complement. Purification, alignment and N-terminal amino acid sequences of the major cyanogen bromide fragments, and localization of the serine residue at the active site.Relation of putative thioester bond in C3 to activation of the alternative pathway and the binding of C3b to biological targets of complement.Mechanisms involved in the regulation of free fatty acid release from isolated human fat cells by acylation-stimulating protein and insulin.The separation of functionally distinct forms of the third component of human complement (C3).Analysis of Factor D Isoforms in Malpuech-Michels-Mingarelli-Carnevale Patients Highlights the Role of MASP-3 as a Maturase in the Alternative Pathway of Complement.Extensive Basal Level Activation of Complement Mannose-Binding Lectin-Associated Serine Protease-3: Kinetic Modeling of Lectin Pathway Activation Provides Possible Mechanism.The properdin pathway: an "alternative activation pathway" or a "critical amplification loop" for C3 and C5 activation?
P2860
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P2860
Mechanism of action of factor D of the alternative complement pathway
description
1978 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1978 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1978
@ast
im Dezember 1978 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
@en
vedecký článok (publikovaný 1978/12/01)
@sk
vědecký článek publikovaný v roce 1978
@cs
wetenschappelijk artikel (gepubliceerd op 1978/12/01)
@nl
наукова стаття, опублікована в грудні 1978
@uk
مقالة علمية (نشرت في ديسمبر 1978)
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name
Mechanism of action of factor D of the alternative complement pathway
@ast
Mechanism of action of factor D of the alternative complement pathway
@en
Mechanism of action of factor D of the alternative complement pathway
@nl
type
label
Mechanism of action of factor D of the alternative complement pathway
@ast
Mechanism of action of factor D of the alternative complement pathway
@en
Mechanism of action of factor D of the alternative complement pathway
@nl
prefLabel
Mechanism of action of factor D of the alternative complement pathway
@ast
Mechanism of action of factor D of the alternative complement pathway
@en
Mechanism of action of factor D of the alternative complement pathway
@nl
P2860
P3181
P356
P1476
Mechanism of action of factor D of the alternative complement pathway
@en
P2093
H. J. Müller-Eberhard
P. H. Lesavre
P2860
P304
P3181
P356
10.1084/JEM.148.6.1498
P407
P577
1978-12-01T00:00:00Z