Functional evaluation of PTEN missense mutations using in vitro phosphoinositide phosphatase assay
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PTEN function: how normal cells control it and tumour cells lose itProtean PTEN: form and functionThe PI3K pathway as drug target in human cancerThe relationship between metallothionein-1F (MT1F) gene and hepatocellular carcinomaTargeting the Phosphatidylinositol-3-kinase Pathway in Gastric Cancer: Can Omics Improve Outcomes?Superdomains in the protein structure hierarchy: The case of PTP-C2PI3K/AKT pathway mutations cause a spectrum of brain malformations from megalencephaly to focal cortical dysplasiaStructural mutation analysis of PTEN and its genotype-phenotype correlations in endometriosis and cancerPhosphoinositide phosphatases in cell biology and disease.Mutational analysis reveals the origin and therapy-driven evolution of recurrent gliomaDifferent mutational characteristics of TSG in cell lines and surgical specimensProtein interactions of phosphatase and tensin homologue (PTEN) and its cancer-associated G20E mutant compared by using stable isotope labeling by amino acids in cell culture-based parallel affinity purification.Mechanistic analysis of a DNA damage-induced, PTEN-dependent size checkpoint in human cellsAKT inhibitors promote cell death in cervical cancer through disruption of mTOR signaling and glucose uptake.PTEN Expression as a Predictor of Response to Focal Adhesion Kinase Inhibition in Uterine Cancer.IQGAP1 and its binding proteins control diverse biological functions.Systematic Functional Interrogation of Rare Cancer Variants Identifies Oncogenic AllelesMutation screening of the PTEN gene in patients with autism spectrum disorders and macrocephaly.Resistance to EGF receptor inhibitors in glioblastoma mediated by phosphorylation of the PTEN tumor suppressor at tyrosine 240.The significance of PTEN and AKT aberrations in pediatric T-cell acute lymphoblastic leukemia.Correction of PTEN mutations in glioblastoma cell lines via AAV-mediated gene editing.Utility of PTEN protein dosage in predicting for underlying germline PTEN mutations among patients presenting with thyroid cancer and Cowden-like phenotypesDisruption of epithelial architecture caused by loss of PTEN or by oncogenic mutant p110α/PIK3CA but not by HER2 or mutant AKT1.Frequent gastrointestinal polyps and colorectal adenocarcinomas in a prospective series of PTEN mutation carriers.PTEN inhibits PREX2-catalyzed activation of RAC1 to restrain tumor cell invasion.Annotating cancer variants and anti-cancer therapeutics in reactome.Evaluating cell lines as tumour models by comparison of genomic profiles.Tumor mutational analysis of GOG248, a phase II study of temsirolimus or temsirolimus and alternating megestrol acetate and tamoxifen for advanced endometrial cancer (EC): An NRG Oncology/Gynecologic Oncology Group studyThe phosphoinositide 3-kinase pathway in human cancer: genetic alterations and therapeutic implications.The genetic landscape of clinical resistance to RAF inhibition in metastatic melanoma.The Biological Role of PI3K Pathway in Lung Cancer.Engineering PTEN function: membrane association and activity.Integrative genome analyses identify key somatic driver mutations of small-cell lung cancerControlling PTEN (Phosphatase and Tensin Homolog) Stability: A DOMINANT ROLE FOR LYSINE 66.Nuclear translocation of fibroblast growth factor-2 (FGF2) is regulated by Karyopherin-β2 and Ran GTPase in human glioblastoma cellsA new class of cancer-associated PTEN mutations defined by membrane translocation defects.PTEN dephosphorylates AKT to prevent the expression of GLUT1 on plasmamembrane and to limit glucose consumption in cancer cellsA mutant form of PTEN linked to autismThe tumour-suppressor function of PTEN requires an N-terminal lipid-binding motif.Cowden's syndrome with immunodeficiency.
P2860
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P2860
Functional evaluation of PTEN missense mutations using in vitro phosphoinositide phosphatase assay
description
2000 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հունիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2000
@ast
im Juni 2000 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2000/06/15)
@sk
vědecký článek publikovaný v roce 2000
@cs
wetenschappelijk artikel (gepubliceerd op 2000/06/15)
@nl
наукова стаття, опублікована в червні 2000
@uk
مقالة علمية (نشرت في 15-6-2000)
@ar
name
Functional evaluation of PTEN ...... phoinositide phosphatase assay
@ast
Functional evaluation of PTEN ...... phoinositide phosphatase assay
@en
Functional evaluation of PTEN ...... phoinositide phosphatase assay
@nl
type
label
Functional evaluation of PTEN ...... phoinositide phosphatase assay
@ast
Functional evaluation of PTEN ...... phoinositide phosphatase assay
@en
Functional evaluation of PTEN ...... phoinositide phosphatase assay
@nl
prefLabel
Functional evaluation of PTEN ...... phoinositide phosphatase assay
@ast
Functional evaluation of PTEN ...... phoinositide phosphatase assay
@en
Functional evaluation of PTEN ...... phoinositide phosphatase assay
@nl
P2093
P1433
P1476
Functional evaluation of PTEN ...... phoinositide phosphatase assay
@en
P2093
R Kanamaru
P304
P407
P577
2000-06-01T00:00:00Z