Predominant expression and activation-induced tyrosine phosphorylation of phospholipase C-gamma 2 in B lymphocytes
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Identification of HS1 protein as a major substrate of protein-tyrosine kinase(s) upon B-cell antigen receptor-mediated signalingIdentification of two tyrosine phosphoproteins, pp70 and pp68, which interact with phospholipase Cgamma, Grb2, and Vav after B cell antigen receptor activationTyrosine phosphorylation of CD19 in pre-B and mature B cellsCbl-b positively regulates Btk-mediated activation of phospholipase C-gamma2 in B cellsRole of the Syk autophosphorylation site and SH2 domains in B cell antigen receptor signalingSignal transduction via CD40 involves activation of lyn kinase and phosphatidylinositol-3-kinase, and phosphorylation of phospholipase C gamma 2The phospholipase C isozymes and their regulationFour tyrosine residues in phospholipase C-gamma 2, identified as Btk-dependent phosphorylation sites, are required for B cell antigen receptor-coupled calcium signalingAltered antigen receptor signaling and impaired Fas-mediated apoptosis of B cells in Lyn-deficient micePhospholipase Cgamma2 provides survival signals via Bcl2 and A1 in different subpopulations of B cellsSyk activation by the Src-family tyrosine kinase in the B cell receptor signalingTec kinases mediate sustained calcium influx via site-specific tyrosine phosphorylation of the phospholipase Cgamma Src homology 2-Src homology 3 linker.Functional independence and interdependence of the Src homology domains of phospholipase C-gamma1 in B-cell receptor signal transduction.Identification of amino acid residues required for a specific interaction between Src-tyrosine kinase and proline-rich region of phosphatidylinositol-3' kinase.Phospholipase C gamma 2 is critical for development of a murine model of inflammatory arthritis by affecting actin dynamics in dendritic cells.Pleiotropic contributions of phospholipase C-gamma1 (PLC-gamma1) to T-cell antigen receptor-mediated signaling: reconstitution studies of a PLC-gamma1-deficient Jurkat T-cell lineUltraviolet radiation rapidly induces tyrosine phosphorylation and calcium signaling in lymphocytes.Fc gamma receptor activation induces the tyrosine phosphorylation of both phospholipase C (PLC)-gamma 1 and PLC-gamma 2 in natural killer cells.Connections between signal transduction components and cellular responses initiated by antigen receptor on B lymphocytes.Immunoglobulin-mediated signal transduction in B cells from CD45-deficient micePhospholipase Cγ2 plays a role in TCR signal transduction and T cell selection.Antisense oligodeoxynucleotides to the blk tyrosine kinase prevent anti-mu-chain-mediated growth inhibition and apoptosis in a B-cell lymphomaEpstein-Barr virus latent membrane protein 2A blocks calcium mobilization in B lymphocytes.Identification of the peptides that stimulate the phosphoinositide hydrolysis in lymphocyte cell lines from peptide libraries.Targeted inhibition of phospholipase C γ2 adaptor function blocks osteoclastogenesis and protects from pathological osteolysis.B cells from patients with systemic lupus erythematosus display abnormal antigen receptor-mediated early signal transduction eventsAnalysis of Ig-alpha-tyrosine kinase interaction reveals two levels of binding specificity and tyrosine phosphorylated Ig-alpha stimulation of Fyn activity.A PLC-γ1 Feedback Pathway Regulates Lck Substrate Phosphorylation at the T-Cell Receptor and SLP-76 Complex.Mitogenic response of murine B lymphocytes to Salmonella typhimurium lipopolysaccharide requires protein kinase C-dependent late tyrosine phosphorylations.Activation of phospholipase C gamma in Schizosaccharomyces pombe by coexpression of receptor or nonreceptor tyrosine kinases.An important role of phospholipase Cgamma1 in pre-B-cell development and allelic exclusion.Role of alterations in Ca(2+)-associated signaling pathways in the immunotoxicity of polycyclic aromatic hydrocarbons.The phospholipase C gamma 1-dependent pathway of Fc epsilon RI-mediated mast cell activation is regulated independently of phosphatidylinositol 3-kinase.Distinct roles of phosphoinositide-3 kinase and phospholipase Cgamma2 in B-cell receptor-mediated signal transduction.Tyrosine kinases Lyn and Syk regulate B cell receptor-coupled Ca2+ mobilization through distinct pathways.Essential role of phospholipase C gamma 2 in early B-cell development and Myc-mediated lymphomagenesis.Requirement of phospholipase C-gamma 2 activation in surface immunoglobulin M-induced B cell apoptosis.Lineage-specific induction of B cell apoptosis and altered signal transduction by the phosphotyrosine phosphatase inhibitor bis(maltolato)oxovanadium(IV).Activation of phospholipase C-gamma 1 through transfected platelet-derived growth factor receptor enhances interleukin 2 production upon antigen stimulation in a T-cell line.Signaling by the B Cell Receptor (BCR)
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P2860
Predominant expression and activation-induced tyrosine phosphorylation of phospholipase C-gamma 2 in B lymphocytes
description
1992 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի հունիսին հրատարակված գիտական հոդված
@hy
article publié dans les Procee ...... f the United States of America
@fr
artículu científicu espublizáu en 1992
@ast
im Juni 1992 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1992/06/15)
@sk
vědecký článek publikovaný v roce 1992
@cs
wetenschappelijk artikel (gepubliceerd op 1992/06/15)
@nl
наукова стаття, опублікована в червні 1992
@uk
name
Predominant expression and act ...... ase C-gamma 2 in B lymphocytes
@ast
Predominant expression and act ...... ase C-gamma 2 in B lymphocytes
@en
Predominant expression and act ...... ase C-gamma 2 in B lymphocytes
@nl
type
label
Predominant expression and act ...... ase C-gamma 2 in B lymphocytes
@ast
Predominant expression and act ...... ase C-gamma 2 in B lymphocytes
@en
Predominant expression and act ...... ase C-gamma 2 in B lymphocytes
@nl
prefLabel
Predominant expression and act ...... ase C-gamma 2 in B lymphocytes
@ast
Predominant expression and act ...... ase C-gamma 2 in B lymphocytes
@en
Predominant expression and act ...... ase C-gamma 2 in B lymphocytes
@nl
P2093
P2860
P356
P1476
Predominant expression and act ...... ase C-gamma 2 in B lymphocytes
@en
P2093
J. C. McHugh
K. M. Coggeshall
P2860
P304
P356
10.1073/PNAS.89.12.5660
P407
P577
1992-06-15T00:00:00Z