Signal transduction through the CD19 receptor during discrete developmental stages of human B-cell ontogeny

Signal transduction through the CD19 receptor during discrete developmental stages of human B-cell ontogeny

Item
http://www.wikidata.org/entity/Q28615752
Membrane-associated CD19-LYN complex is an endogenous p53-independent and Bc1-2-independent regulator of apoptosis in human B-lineage lymphoma cellsThe motheaten mutation rescues B cell signaling and development in CD45-deficient miceQualitative regulation of B cell antigen receptor signaling by CD19: selective requirement for PI3-kinase activation, inositol-1,4,5-trisphosphate production and Ca2+ mobilizationA novel subset of memory B cells is enriched in autoreactivity and correlates with adverse outcomes in SLEThe CD19 signal transduction molecule is a response regulator of B-lymphocyte differentiation.STAT3 is a substrate of SYK tyrosine kinase in B-lineage leukemia/lymphoma cells exposed to oxidative stress.CD19-antigen specific nanoscale liposomal formulation of a SYK P-site inhibitor causes apoptotic destruction of human B-precursor leukemia cells.Recombinant human CD19L-sTRAIL effectively targets B cell precursor acute lymphoblastic leukemia.A c-Myc and surface CD19 signaling amplification loop promotes B cell lymphoma development and progression in mice.CD19 has a potential CD77 (globotriaosyl ceramide)-binding site with sequence similarity to verotoxin B-subunits: implications of molecular mimicry for B cell adhesion and enterohemorrhagic Escherichia coli pathogenesis.Immunoglobulin recombinase gene activity is modulated reciprocally by interleukin 7 and CD19 in B cell progenitors.CD19 and CD22 expression reciprocally regulates tyrosine phosphorylation of Vav protein during B lymphocyte signaling.Antiviral protection and germinal center formation, but impaired B cell memory in the absence of CD19.The early activation of memory B cells from Wiskott-Aldrich syndrome patients is suppressed by CD19 downregulation.Signalosomes assemble at the activated BCRp-CD19:VAV binds PI3K and GRB2
P2860

Signal transduction through the CD19 receptor during discrete developmental stages of human B-cell ontogeny

Item
http://www.wikidata.org/entity/Q28615752
description
1993 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 1993
@ast
im Oktober 1993 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1993/10/05)
@sk
vědecký článek publikovaný v roce 1993
@cs
wetenschappelijk artikel (gepubliceerd op 1993/10/05)
@nl
наукова стаття, опублікована в жовтні 1993
@uk
name
Signal transduction through th ...... tages of human B-cell ontogeny
@ast
Signal transduction through th ...... tages of human B-cell ontogeny
@en
Signal transduction through th ...... tages of human B-cell ontogeny
@nl
type
label
Signal transduction through th ...... tages of human B-cell ontogeny
@ast
Signal transduction through th ...... tages of human B-cell ontogeny
@en
Signal transduction through th ...... tages of human B-cell ontogeny
@nl
prefLabel
Signal transduction through th ...... tages of human B-cell ontogeny
@ast
Signal transduction through th ...... tages of human B-cell ontogeny
@en
Signal transduction through th ...... tages of human B-cell ontogeny
@nl
P1433
P1476
P2093
P304
P31
P407
P433
P478
P50
P577
P698
P1433
P1476
Signal transduction through th ...... tages of human B-cell ontogeny
@en
P2093
P304
P31
P407
P433
P478
P50
P577
P698