Human glutamine phosphoribosylpyrophosphate amidotransferase. Kinetic and regulatory properties
about
Mutant feedback-resistant phosphoribosylpyrophosphate synthetase associated with purine overproduction and gout. Phosphoribosylpyrophosphate and purine metabolism in cultured fibroblasts2'-deoxyguanosine toxicity for B and mature T lymphoid cell lines is mediated by guanine ribonucleotide accumulationEvidence for X-linkage of human phosphoribosylpyrophosphate synthetase.Small elevations of glucose concentration redirect and amplify the synthesis of guanosine 5'-triphosphate in rat isletsMolecular variation in relation to purine metabolismA purine auxotroph deficient in phosphoribosylpyrophosphate amidotransferase and phosphoribosylpyrophosphate aminotransferase activities with normal activity of ribose-5-phosphate aminotransferase.Clinical and biochemical studies on treatment of Lesch-Nyhan syndrome.Patterns of phosphoribosylpyrophosphate and ribose-5-phosphate concentration and generation in fibroblasts from patients with gout and purine overproductionPurine oversecretion in cultured murine lymphoma cells deficient in adenylosuccinate synthetase: genetic model for inherited hyperuricemia and goutBasis for the control of purine biosynthesis by purine ribonucleotides.Purine metabolism in cultured human fibroblasts derived from patients deficient in hypoxanthine phosphoribosyltransferase, purine nucleoside phosphorylase, or adenosine deaminase.A New View into the Regulation of Purine Metabolism: The Purinosome.A reappraisal of the concept of an abnormality of glutamine metabolism in primary gout.De novo purine synthesis in vegetative cells and myxospores of Myxococcus xanthus.The kinetics of intramolecular distribution of 15N in uric acid after administration of (15N) glycine. A reappraisal of the significance of preferential labeling of N-(3+9) of uric acid in primary gout.De novo synthesis of purine nucleotides in human peripheral blood leukocytes. Excessive activity of the pathway in hypoxanthine-guanine phosphoribosyltransferase deficiency.Comparative study of 6-mercaptopurine metabolism in human leukemic leukocytes and L1210 cells.Purine biosynthesis, riboflavin production, and trophic-phase span are controlled by a Myb-related transcription factor in the fungus Ashbya gossypii.Phosphoribosyl pyrophosphate synthetase activity affects growth and riboflavin production in Ashbya gossypii.Purine deoxynucleosides and adenosine dialdehyde decrease 5-amino-4-imidazolecarboxamide (Z-base)-dependent purine nucleotide synthesis in cultured T and B lymphoblastsMetabolic engineering of the purine pathway for riboflavin production in Ashbya gossypii.Formation of phosphoribosyl pyrophosphate amidotransferase tetramerDissociation of phosphoribosyl pyrophosphate amidotransferase tetramer5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate
P2860
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P2860
Human glutamine phosphoribosylpyrophosphate amidotransferase. Kinetic and regulatory properties
description
1973 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1973 թվականի հունվարին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 1973
@ast
im Januar 1973 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1973/01/10)
@sk
vědecký článek publikovaný v roce 1973
@cs
wetenschappelijk artikel (gepubliceerd op 1973/01/10)
@nl
наукова стаття, опублікована в січні 1973
@uk
name
Human glutamine phosphoribosyl ...... etic and regulatory properties
@ast
Human glutamine phosphoribosyl ...... etic and regulatory properties
@en
Human glutamine phosphoribosyl ...... etic and regulatory properties
@nl
type
label
Human glutamine phosphoribosyl ...... etic and regulatory properties
@ast
Human glutamine phosphoribosyl ...... etic and regulatory properties
@en
Human glutamine phosphoribosyl ...... etic and regulatory properties
@nl
prefLabel
Human glutamine phosphoribosyl ...... etic and regulatory properties
@ast
Human glutamine phosphoribosyl ...... etic and regulatory properties
@en
Human glutamine phosphoribosyl ...... etic and regulatory properties
@nl
P2093
P1476
Human glutamine phosphoribosyl ...... etic and regulatory properties
@en
P2093
E. W. Holmes
J. B. Wyngaarden
J. M. McCord
W. N. Kelley
P304
P407
P577
1973-01-10T00:00:00Z