Heparin-binding EGF-like growth factor, which acts as the diphtheria toxin receptor, forms a complex with membrane protein DRAP27/CD9, which up-regulates functional receptors and diphtheria toxin sensitivity

Heparin-binding EGF-like growth factor, which acts as the diphtheria toxin receptor, forms a complex with membrane protein DRAP27/CD9, which up-regulates functional receptors and diphtheria toxin sensitivity

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http://www.wikidata.org/entity/Q28631171

Q28631171

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Hepatocyte permissiveness to Plasmodium infection is conveyed by a short and structurally conserved region of the CD81 large extracellular domain Latent transforming growth factor beta-binding protein-3 and fibulin-1C interact with the extracellular domain of the heparin-binding EGF-like growth factor precursor Dynamic regulation of a GPCR-tetraspanin-G protein complex on intact cells: central role of CD81 in facilitating GPR56-Galpha q/11 association A metalloprotease-disintegrin, MDC9/meltrin-gamma/ADAM9 and PKCdelta are involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor.Function of the tetraspanin CD151-alpha6beta1 integrin complex during cellular morphogenesis Heparin-binding epidermal growth factor-like growth factor/diphtheria toxin receptor in normal and neoplastic hematopoiesis Novel CD9-targeted therapies in gastric cancer Heparin-binding EGF-like growth factor and ErbB signaling is essential for heart function Cysteine residues in the large extracellular loop (EC2) are essential for the function of the stress-regulated glycoprotein M6a Characterization of mice lacking the tetraspanin superfamily member CD151 The Hsp90 machinery facilitates the transport of diphtheria toxin into human cells Sensitivity of cancer cells to truncated diphtheria toxin.CD9 is associated with leukemia inhibitory factor-mediated maintenance of embryonic stem cells.The tetraspanins CD9 and CD81 regulate CD9P1-induced effects on cell migration.Heparin binding epidermal growth factor-like growth factor and PD169316 prevent apoptosis in mouse embryonic stem cells Tetraspanin CO-029 inhibits colorectal cancer cell movement by deregulating cell-matrix and cell-cell adhesions A novel cholesterol-insensitive mode of membrane binding promotes cytolysin-mediated translocation by Streptolysin O Phorbol ester induces the rapid processing of cell surface heparin-binding EGF-like growth factor: conversion from juxtacrine to paracrine growth factor activity Isolation of a human monoclonal antibody with strong neutralizing activity against diphtheria toxin.Heparin-binding epidermal growth factor-like growth factor is a potent neurotrophic factor for PC12 cells Cooperative role for tetraspanins in adhesin-mediated attachment of bacterial species to human epithelial cells The mitogenic potential of heparin-binding epidermal growth factor in the human endometrium is mediated by the epidermal growth factor receptor and is modulated by tumor necrosis factor-alpha.The C-terminal tail of tetraspanin protein CD9 contributes to its function and molecular organization Mechanism of diphtheria toxin catalytic domain delivery to the eukaryotic cell cytosol and the cellular factors that directly participate in the process.CD9, a tetraspan transmembrane protein, renders cells susceptible to canine distemper virus.Blocking of feline immunodeficiency virus infection by a monoclonal antibody to CD9 is via inhibition of virus release rather than interference with receptor binding The membrane protein CD9/DRAP 27 potentiates the juxtacrine growth factor activity of the membrane-anchored heparin-binding EGF-like growth factor The tetraspanin CD9 associates with transmembrane TGF-alpha and regulates TGF-alpha-induced EGF receptor activation and cell proliferation.Targeting of tetraspanin proteins--potential benefits and strategies Membrane-anchored heparin-binding EGF-like growth factor (HB-EGF) and diphtheria toxin receptor-associated protein (DRAP27)/CD9 form a complex with integrin alpha 3 beta 1 at cell-cell contact sites.Clinical significance of heparin-binding epidermal growth factor-like growth factor in peritoneal fluid of ovarian cancer The anti-tumour agent, cisplatin, and its clinically ineffective isomer, transplatin, produce unique gene expression profiles in human cells Distinct mechanisms of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrimidine resistance revealed by transcriptome mapping in mouse striatum.Recombinant immunotoxins containing truncated bacterial toxins for the treatment of hematologic malignancies GPI-anchored diphtheria toxin receptor allows membrane translocation of the toxin without detectable ion channel activity.Characterization of a Novel Anti-Human HB-EGF Monoclonal Antibody Applicable for Paraffin-Embedded Tissues and Diagnosis of HB-EGF-Related Cancers.Heparin-binding EGF-like growth factor enhances the activity of invasion and metastasis in thyroid cancer cells.Ligand-independent dimer formation of epidermal growth factor receptor (EGFR) is a step separable from ligand-induced EGFR signaling.Receptor-based antidote for diphtheria.Heparin-binding EGF-like growth factor is an autocrine growth factor for human urothelial cells and is synthesized by epithelial and smooth muscle cells in the human bladder.

P2860

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P2860

Heparin-binding EGF-like growth factor, which acts as the diphtheria toxin receptor, forms a complex with membrane protein DRAP27/CD9, which up-regulates functional receptors and diphtheria toxin sensitivity

Item

http://www.wikidata.org/entity/Q28631171

description

1994 թուականի Մայիսին հրատարակուած գիտական յօդուած

@hyw

1994 թվականի մայիսին հրատարակված գիտական հոդված

@hy

artículu científicu espublizáu en 1994

@ast

im Mai 1994 veröffentlichter wissenschaftlicher Artikel

@de

scientific journal article

@en

vedecký článok (publikovaný 1994/05/15)

@sk

vědecký článek publikovaný v roce 1994

@cs

wetenschappelijk artikel (gepubliceerd op 1994/05/15)

@nl

наукова стаття, опублікована в травні 1994

@uk

مقالة علمية (نشرت في 15-5-1994)

@ar