Seeing the light: preassembly and ligand-induced changes of the interferon gamma receptor complex in cells
about
The human interleukin-6 (IL-6) receptor exists as a preformed dimer in the plasma membraneA model of the ternary complex of interleukin-10 with its soluble receptors.Chaperone Hsp27, a novel subunit of AUF1 protein complexes, functions in AU-rich element-mediated mRNA decayMacrophages and cytokines in the early defence against herpes simplex virusDifferential effects of type I and II interferons on myeloid cells and resistance to intracellular bacterial infectionsCytokines: their role in stroke and potential use as biomarkers and therapeutic targetsReceptor dimerization dynamics as a regulatory valve for plasticity of type I interferon signalingLive cell micropatterning reveals the dynamics of signaling complexes at the plasma membraneThe C-terminus of interferon gamma receptor beta chain (IFNgammaR2) has antiapoptotic activity as a Bax inhibitor.Evidence for ligand-independent multimerization of the IL-17 receptor.Forced dimerization of gp130 leads to constitutive STAT3 activation, cytokine-independent growth, and blockade of differentiation of embryonic stem cells.The receptor kinases LePRK1 and LePRK2 associate in pollen and when expressed in yeast, but dissociate in the presence of style extract.Understanding cytokine and growth factor receptor activation mechanisms.Interleukin-5 receptor subunit oligomerization and rearrangement revealed by fluorescence resonance energy transfer imagingStructure-function relationships in the IL-17 receptor: implications for signal transduction and therapyAnalytical use of multi-protein Fluorescence Resonance Energy Transfer to demonstrate membrane-facilitated interactions within cytokine receptor complexesLigand-independent interaction of the type I interferon receptor complex is necessary to observe its biological activity.Computational models of the JAK1/2-STAT1 signalingPartial IFN-γR2 deficiency is due to protein misfolding and can be rescued by inhibitors of glycosylation.Visualization of protein interactions in living cells.Structural conservation of interferon gamma among vertebrates.Improving the spectral analysis of Fluorescence Resonance Energy Transfer in live cells: application to interferon receptors and Janus kinases.Receptor tyrosine kinase signaling--a proteomic perspective.TCR Nanoclusters as the Framework for Transmission of Conformational Changes and Cooperativity.STATs dimerize in the absence of phosphorylation.Type I Interferon Signaling Is Decoupled from Specific Receptor Orientation through Lenient Requirements of the Transmembrane Domain.Synthetic Deletion of the Interleukin 23 Receptor (IL-23R) Stalk Region Led to Autonomous IL-23R Homodimerization and Activation.IFN-γR1 defects: Mutation update and description of the IFNGR1 variation database.Chaperone Hsp27 modulates AUF1 proteolysis and AU-rich element-mediated mRNA degradation.Forced homo- and heterodimerization of all gp130-type receptor complexes leads to constitutive ligand-independent signaling and cytokine-independent growth.Palmitoylation of interferon-alpha (IFN-alpha) receptor subunit IFNAR1 is required for the activation of Stat1 and Stat2 by IFN-alpha.Modulation of the activation of Stat1 by the interferon-gamma receptor complex.Leptin receptor activation depends on critical cysteine residues in its fibronectin type III subdomains.Visualization of Protein Interactions in Living Cells.Ligand-induced type II interleukin-4 receptor dimers are sustained by rapid re-association within plasma membrane microcompartments.Dynamics of the gp130 cytokine complex: a model for assembly on the cellular membrane.Re-evaluation of IL-10 signaling reveals novel insights on the contribution of the intracellular domain of the IL-10R2 chain.Dynamic Modulation of Binding Affinity as a Mechanism for Regulating Interferon Signaling.Interaction of IFNG with IFNGRPreassembly and ligand-induced restructuring of the chains of the IFN-gamma receptor complex: the roles of Jak kinases, Stat1 and the receptor chains.
P2860
Q24297675-BBB830CD-FF26-47C8-8604-190A01076F39Q24530097-131C1A89-0FC5-484C-BD29-28F36EECE223Q24658102-98A296E5-E0B0-4480-93E6-AA7AADE5128CQ24815062-5CA2740C-97F7-418F-957D-ADB4182EA0F2Q26849516-661211AA-7994-405D-8620-5D617AE46522Q26998414-8980C0EB-46EA-4CCA-882B-77858B79EAD2Q27310374-8CD08FAF-B5AB-4B52-AA61-6A554AF1BDD1Q30597262-EAB1EB70-2574-4774-9CF3-761A52D10C3BQ34081110-D7F04141-DCF0-42CD-BB48-ABC292A099A0Q34279731-04E96766-FAED-4034-A6A9-49096AF4847CQ34698039-4FDFEE48-145B-452F-A097-9A729D95C1D9Q35144556-D5348BEE-823E-476E-AC04-E4A2D1CBAD21Q36509470-9C377871-50FC-4C34-9A9F-35390F864B82Q36741561-866B2D45-1C65-4AA8-B8AA-6FC4B4DCB4FDQ37051768-B360963F-1627-43AD-AFD4-F84FB4B3D0DBQ37164852-9D7E3390-80D1-4BD1-956F-43E113128AA6Q37164886-0C3BE6B4-0BA6-4932-A776-7D733D385FC0Q37168136-C35BECB7-4236-42DD-8A1F-2609784D6362Q37215141-BDD231B7-0792-4B37-AA36-2453D75E3A4EQ37344383-5F929AC4-B667-483E-9360-93D51B35232CQ37370513-ECF98C22-6744-43DF-BEC7-92F5FA65D649Q37403815-B3A6AED6-09DE-49A6-8056-C37445C896EEQ37807745-7C9B718A-F2A9-4AAC-A255-F291697E5642Q38009792-E6E67494-4013-4A26-8FD3-5F823CB2B075Q38353169-9D9F6D46-EBDE-4B6B-8905-1EBF122164C5Q38378144-3B95A8FB-2E88-408C-9AA0-33B4FA68DA7FQ38718364-91EB0E26-C807-4091-B3C5-FC2D90850919Q39458875-A449AF13-AD24-4FBB-BE76-8E1F64AF1BC0Q39606122-F97C35B6-DD22-40F6-8245-667A9D9B794AQ39691985-BA10561D-1077-4B1B-ADB1-0E55F66190E0Q39832097-2D0F6A45-EAEF-450D-BC3E-2DAC37393C51Q40318695-A5FB238B-7D3C-48B4-96D8-DBE6D2467CBDQ40433191-61BF77EF-88C1-4F78-8D85-23E4F7D8C740Q40751195-FC6BB43C-BE6F-488E-A99D-5E012E7A9D92Q41077405-301F266B-C66D-408F-B93F-225BB21ACF5DQ42158045-78F4EDE2-1E42-4E21-86D9-2D634BF460F6Q42706642-385C7D29-30E4-4896-8866-DA1FD604DEC9Q47565835-6BA3667B-095A-4B57-A8D7-2BB0F68DF936Q50292439-6A93FF8F-3C42-4700-9FE1-24C9C6CB45D5Q50335881-C41A3119-091C-4721-8BF7-4A7A5C384FA4
P2860
Seeing the light: preassembly and ligand-induced changes of the interferon gamma receptor complex in cells
description
2002 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2002
@ast
scientific journal article
@en
vedecký článok (publikovaný 2002/10/01)
@sk
vědecký článek publikovaný v roce 2002
@cs
wetenschappelijk artikel (gepubliceerd op 2002/10/01)
@nl
wissenschaftlicher Artikel
@de
наукова стаття, опублікована в жовтні 2002
@uk
مقالة علمية (نشرت في أكتوبر 2002)
@ar
name
Seeing the light: preassembly ...... amma receptor complex in cells
@ast
Seeing the light: preassembly ...... amma receptor complex in cells
@en
Seeing the light: preassembly ...... amma receptor complex in cells
@nl
type
label
Seeing the light: preassembly ...... amma receptor complex in cells
@ast
Seeing the light: preassembly ...... amma receptor complex in cells
@en
Seeing the light: preassembly ...... amma receptor complex in cells
@nl
prefLabel
Seeing the light: preassembly ...... amma receptor complex in cells
@ast
Seeing the light: preassembly ...... amma receptor complex in cells
@en
Seeing the light: preassembly ...... amma receptor complex in cells
@nl
P2093
P2860
P1476
Seeing the light: preassembly ...... amma receptor complex in cells
@en
P2093
Christopher D. Krause
Junxia Xie
Martin A. Bopp
Robin M. Hochstrasser
Sidney Pestka
P2860
P304
P356
10.1074/MCP.M200065-MCP200
P577
2002-10-01T00:00:00Z