Characteristics of human types 1, 2 and 3 17 beta-hydroxysteroid dehydrogenase activities: oxidation/reduction and inhibition
about
The molecular biology, biochemistry, and physiology of human steroidogenesis and its disordersIn silico discovery of gene-coding variants in murine quantitative trait loci using strain-specific genome sequence databasesUnusual charge stabilization of NADP+ in 17beta-hydroxysteroid dehydrogenasePurification, reconstitution, and steady-state kinetics of the trans-membrane 17 beta-hydroxysteroid dehydrogenase 2Human oestrogenic 17beta-hydroxysteroid dehydrogenase specificity: enzyme regulation through an NADPH-dependent substrate inhibition towards the highly specific oestrone reductionPlacenta defects and embryonic lethality resulting from disruption of mouse hydroxysteroid (17-beta) dehydrogenase 2 geneExpression and localization of estrogenic type 12 17beta-hydroxysteroid dehydrogenase in the cynomolgus monkeyMolecular characterization of a first human 3(alpha-->beta)-hydroxysteroid epimerase.Chemopreventive and adjuvant therapeutic potential of pomegranate (Punica granatum) for human breast cancer.Variation in AKR1C3, which encodes the neuroactive steroid synthetic enzyme 3α-HSD type 2 (17β-HSD type 5), moderates the subjective effects of alcoholType 2 17-β hydroxysteroid dehydrogenase as a novel target for the treatment of osteoporosis.Dehydroepiandrosterone, androgens and the mammary gland.In vivo and in vitro expression of steroid-converting enzymes in human breast tumours: associations with interleukin-6.Androstenedione up-regulation of endometrial aromatase expression via local conversion to estrogen: potential relevance to the pathogenesis of endometriosis.17beta-Hydroxysteroid dehydrogenase inhibitors: a patent review.Regulation of 17β-hydroxysteroid dehydrogenases in cancer: regulating steroid receptor at pre-receptor stage.Coumarin-based drugs: a patent review (2008 -- present).Assessment of steroidogenic pathways that do not require testosterone as intermediate.Biochemical factors governing the steady-state estrone/estradiol ratios catalyzed by human 17beta-hydroxysteroid dehydrogenases types 1 and 2 in HEK-293 cells.Conversion of pregnenolone to DHEA by human 17alpha-hydroxylase/17, 20-lyase (P450c17). Evidence that DHEA is produced from the released intermediate, 17alpha-hydroxypregnenolone.Intravaginal DHEA, by a strictly local action, exerts beneficial effects on both vaginal atrophy symptoms and sexual dysfunction.Local production of neurostradiol affects gonadotropin-releasing hormone (GnRH) secretion at mid-gestation in Lagostomus maximus (Rodentia, Caviomorpha).Impairment of spermatogenesis in rats by mercuric chloride: involvement of low 17β-estradiol level in induction of acute oxidative stress.Comparison of crystal structures of human type 3 3alpha-hydroxysteroid dehydrogenase reveals an "induced-fit" mechanism and a conserved basic motif involved in the binding of androgen.Inhibitors of human and rat testes microsomal 17beta-hydroxysteroid dehydrogenase (17beta-HSD) as potential agents for prostatic cancer.Characterization of 17beta-hydroxysteroid dehydrogenase activity in brain tissue: testosterone formation in the human temporal lobe.Reduction of androstenedione to testosteroneComparative investigation of the in vitro inhibitory potencies of 13-epimeric estrones and D-secoestrones towards 17β-hydroxysteroid dehydrogenase type 1.Bone formation transcripts dominate the differential gene expression profile in an equine osteoporotic condition associated with pulmonary silicosis.Synthesis of a First Estradiol-Adenosine Hybrid Compound
P2860
Q24613957-6CF0CD36-C515-4871-91D0-834000617D14Q24803334-845A696C-DE17-486F-AC92-6AD5DE75E078Q27749016-8B3C0421-50A8-4A46-9093-D87E44A0F222Q28213668-5D77633D-4B70-4406-A932-7620DAC7CC91Q28364303-14D57F7F-4F54-4231-BD68-AEC011C3D2DDQ28507425-47E812CC-A4B1-4C4C-A691-B9B306DE279AQ33272206-6186D6B3-268C-416D-B431-D6A95A723138Q33909706-F5552DE7-4CEC-4813-A018-1F175B127C6AQ33959031-9109679A-9145-4DDA-88D6-7D9656583160Q34054066-7EF257AB-14BE-4C6E-9528-70FC8AECCDEDQ34487793-BD19FD9B-953E-4EEB-9D0C-73161593F53EQ36533630-5415CEBC-A984-4A66-8657-8A0273452701Q36619710-CAD142D4-7D60-40E0-AC6C-D6462D131CC9Q36938355-933372CA-B130-4D38-8A47-BC0E2BE22417Q37774374-01F4B563-A268-4CF1-84CD-CE00C74A1B3AQ37989094-CF6EA235-A0AA-4DE1-B0EF-3F411FFC8D2CQ37999915-CD9D402E-0F1F-460F-9706-1B69E3626E49Q38471547-DCCD6967-17E3-4816-ADE1-6BF99DF7B498Q39833069-C5480668-48AB-4CC9-882A-2962C75D7EEEQ40877922-63D01451-CB4F-4099-A9BD-2F7D6FDCA83CQ40953559-6A61EE7D-E9FA-4B89-AA35-0F33307D026CQ42378095-A627CEEE-CBCB-48B9-A760-0A937343F444Q42915860-CCF29872-BDF7-42B7-B7DB-59AE952A4FF1Q43057981-F461BF62-1038-4D86-9102-49EA53B65E31Q43702160-1F11BF9E-28B1-4041-BC4B-A54A80CA5FE3Q48204784-E2F7047D-DC5D-4ACD-A8D5-E22E8D6D518BQ50294302-6C76FE0F-B58C-4028-A37F-BB56338285DDQ51636762-DE06D213-4968-4CBB-8D05-53D8C0EA459BQ55252520-5F178CEE-A525-41A1-A996-B87AAE83FCCEQ56764589-A5BDBF4D-FF03-4A54-B1D1-35874680874E
P2860
Characteristics of human types 1, 2 and 3 17 beta-hydroxysteroid dehydrogenase activities: oxidation/reduction and inhibition
description
1995 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1995
@ast
scientific journal article
@en
vedecký článok (publikovaný 1995/12/01)
@sk
vědecký článek publikovaný v roce 1995
@cs
wetenschappelijk artikel (gepubliceerd op 1995/12/01)
@nl
наукова стаття, опублікована в грудні 1995
@uk
مقالة علمية (نشرت في ديسمبر 1995)
@ar
name
Characteristics of human types ...... ation/reduction and inhibition
@ast
Characteristics of human types ...... ation/reduction and inhibition
@en
Characteristics of human types ...... ation/reduction and inhibition
@nl
type
label
Characteristics of human types ...... ation/reduction and inhibition
@ast
Characteristics of human types ...... ation/reduction and inhibition
@en
Characteristics of human types ...... ation/reduction and inhibition
@nl
prefLabel
Characteristics of human types ...... ation/reduction and inhibition
@ast
Characteristics of human types ...... ation/reduction and inhibition
@en
Characteristics of human types ...... ation/reduction and inhibition
@nl
P2093
P1476
Characteristics of human types ...... ation/reduction and inhibition
@en
P2093
P304
P356
10.1016/0960-0760(95)00209-X
P577
1995-12-01T00:00:00Z