Human acetyl-CoA carboxylase 2. Molecular cloning, characterization, chromosomal mapping, and evidence for two isoforms
about
The subcellular localization of acetyl-CoA carboxylase 2Cloning of human acetyl-CoA carboxylase beta promoter and its regulation by muscle regulatory factorsMutant mice lacking acetyl-CoA carboxylase 1 are embryonically lethalThe human ACC2 CT-domain C-terminus is required for full functionality and has a novel twistAcetyl-CoA carboxylase 2 mutant mice are protected against obesity and diabetes induced by high-fat/high-carbohydrate dietsStructure-guided Inhibitor Design for Human Acetyl-coenzyme A Carboxylase by Interspecies Active Site ConversionBimodal activation of acetyl-CoA carboxylase by glutamateGlucose and fat metabolism in adipose tissue of acetyl-CoA carboxylase 2 knockout miceIsozyme-nonselective N-substituted bipiperidylcarboxamide acetyl-CoA carboxylase inhibitors reduce tissue malonyl-CoA concentrations, inhibit fatty acid synthesis, and increase fatty acid oxidation in cultured cells and in experimental animalsReduced heart size and increased myocardial fuel substrate oxidation in ACC2 mutant miceHepatic de novo lipogenesis is present in liver-specific ACC1-deficient miceMuscle Carnitine Palmitoyltransferase II Deficiency: A Review of Enzymatic Controversy and Clinical FeaturesRegulator of fatty acid metabolism, acetyl coenzyme a carboxylase 1, controls T cell immunity.A single nucleotide polymorphism within the acetyl-coenzyme A carboxylase beta gene is associated with proteinuria in patients with type 2 diabetes.Elucidation of a promoter activity that directs the expression of acetyl-CoA carboxylase alpha with an alternative N-terminus in a tissue-restricted fashion.Comparative Approach of the de novo Fatty Acid Synthesis (Lipogenesis) between Ruminant and Non Ruminant Mammalian Species: From Biochemical Level to the Main Regulatory Lipogenic Genes.Holocarboxylase synthetase is an obligate participant in biotin-mediated regulation of its own expression and of biotin-dependent carboxylases mRNA levels in human cells.Human acetyl-CoA carboxylase 2 expressed in silkworm Bombyx mori exhibits posttranslational biotinylation and phosphorylation.Alternative usages of multiple promoters of the acetyl-CoA carboxylase beta gene are related to differential transcriptional regulation in human and rodent tissues.Spot14/Mig12 heterocomplex sequesters polymerization and restrains catalytic function of human acetyl-CoA carboxylase 2.Liver-specific deletion of acetyl-CoA carboxylase 1 reduces hepatic triglyceride accumulation without affecting glucose homeostasisHuman cytomegalovirus induces the activity and expression of acetyl-coenzyme A carboxylase, a fatty acid biosynthetic enzyme whose inhibition attenuates viral replicationAcetyl-CoA carboxylase 2-/- mutant mice are protected against fatty liver under high-fat, high-carbohydrate dietary and de novo lipogenic conditions.Glucagon regulates ACC activity in adipocytes through the CAMKKβ/AMPK pathway.Treating the metabolic syndrome: acetyl-CoA carboxylase inhibition.AMP-activated protein kinase--the fat controller of the energy railroad.AMP-activated protein kinase in the brain.Acetyl-CoA carboxylase-alpha inhibitor TOFA induces human cancer cell apoptosisThe Randle cycle revisited: a new head for an old hat.Fatty acid metabolism: target for metabolic syndrome.AMPK and the biochemistry of exercise: implications for human health and disease.Role of the AMP-activated protein kinase in regulating fatty acid metabolism during exercise.Intestinal fatty acid binding protein regulates mitochondrion beta-oxidation and cholesterol uptake.PHD3 Loss in Cancer Enables Metabolic Reliance on Fatty Acid Oxidation via Deactivation of ACC2.Is hepatic lipogenesis fundamental for NAFLD/NASH? A focus on the nuclear receptor coactivator PGC-1β.Malonyl-CoA metabolism in cardiac myocytesPhosphatidylinositol 3-kinase-dependent modulation of carnitine palmitoyltransferase 1A expression regulates lipid metabolism during hematopoietic cell growth.Reciprocal regulation of acetyl-CoA carboxylase 1 and senescence in human fibroblasts involves oxidant mediated p38 MAPK activation.Promoter I of the ovine acetyl-CoA carboxylase-alpha gene: an E-box motif at -114 in the proximal promoter binds upstream stimulatory factor (USF)-1 and USF-2 and acts as an insulin-response sequence in differentiating adipocytes5'-AMP-activated protein kinase activity is elevated early during primary brain tumor development in the rat.
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P2860
Human acetyl-CoA carboxylase 2. Molecular cloning, characterization, chromosomal mapping, and evidence for two isoforms
description
1997 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 1997
@ast
im April 1997 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1997/04/18)
@sk
vědecký článek publikovaný v roce 1997
@cs
wetenschappelijk artikel (gepubliceerd op 1997/04/18)
@nl
наукова стаття, опублікована у квітні 1997
@uk
name
Human acetyl-CoA carboxylase 2 ...... and evidence for two isoforms
@ast
Human acetyl-CoA carboxylase 2 ...... and evidence for two isoforms
@en
Human acetyl-CoA carboxylase 2 ...... and evidence for two isoforms
@nl
type
label
Human acetyl-CoA carboxylase 2 ...... and evidence for two isoforms
@ast
Human acetyl-CoA carboxylase 2 ...... and evidence for two isoforms
@en
Human acetyl-CoA carboxylase 2 ...... and evidence for two isoforms
@nl
prefLabel
Human acetyl-CoA carboxylase 2 ...... and evidence for two isoforms
@ast
Human acetyl-CoA carboxylase 2 ...... and evidence for two isoforms
@en
Human acetyl-CoA carboxylase 2 ...... and evidence for two isoforms
@nl
P2093
P2860
P356
P1476
Human acetyl-CoA carboxylase 2 ...... and evidence for two isoforms
@en
P2093
D B Almarza-Ortega
P2860
P304
10669-10677
P356
10.1074/JBC.272.16.10669
P407
P577
1997-04-01T00:00:00Z