Galectin-9 controls the therapeutic activity of 4-1BB-targeting antibodies
about
Principles of antibody-mediated TNF receptor activationTrial Watch: Immunomodulatory monoclonal antibodies for oncological indications4-1BB Agonists: Multi-Potent Potentiators of Tumor ImmunityTherapeutic potential of anti-CD137 (4-1BB) monoclonal antibodies.Impact of Exogenous Galectin-9 on Human T Cells: CONTRIBUTION OF THE T CELL RECEPTOR COMPLEX TO ANTIGEN-INDEPENDENT ACTIVATION BUT NOT TO APOPTOSIS INDUCTION.Reduced Expression of Galectin-9 Contributes to a Poor Outcome in Colon Cancer by Inhibiting NK Cell Chemotaxis Partially through the Rho/ROCK1 Signaling PathwayThe TNF Receptor Superfamily in Co-stimulating and Co-inhibitory ResponsesF-fucoidan from Saccharina japonica is a novel inducer of galectin-9 and exhibits anti-allergic activityBlockage of Galectin-receptor Interactions by α-lactose Exacerbates Plasmodium berghei-induced Pulmonary Immunopathology.The bitter side of sweet: the role of Galectin-9 in immunopathogenesis of viral infections.Deciphering CD137 (4-1BB) signaling in T-cell costimulation for translation into successful cancer immunotherapy.Dectin 1 activation on macrophages by galectin 9 promotes pancreatic carcinoma and peritumoral immune tolerance.Galectin-9: From cell biology to complex disease dynamics.Galectin-9 binds to O-glycans on protein disulfide isomerase.CD14+ monocyte-derived galectin-9 induces natural killer cell cytotoxicity in chronic hepatitis C.Identification of a p53 target, CD137L, that mediates growth suppression and immune response of osteosarcoma cells.4-1BB ligand signaling to T cells limits T cell activation.Regulatory T Cell-Mediated Suppression of Inflammation Induced by DR3 Signaling Is Dependent on Galectin-9.Crystal structure of murine 4-1BB and its interaction with 4-1BBL support a role for galectin-9 in 4-1BB signaling.Acute Stimulation Generates Tim-3-expressing Th1-type CD4 T Cells That Persist In Vivo and Show Enhanced Effector Function.Role of Galectins in Tumors and in Clinical Immunotherapy.Current perspectives of SA-4-1BBL in immune modulation during cancer.Potential effect of tumor-specific Treg-targeted antibodies in the treatment of human cancers: A bioinformatics analysis.CD137-CRDI is not necessary in the role of contacting its natural ligand.A disintegrin and metalloprotease-17 and galectin-9 are important regulators of local 4-1BB activity and disease outcome in rheumatoid arthritis.Regulation of TNF-Related Apoptosis-Inducing Ligand Signaling by Glycosylation.Adaptive NKG2C+CD57+ Natural Killer Cell and Tim-3 Expression During Viral Infections.Not All Immune Checkpoints Are Created EqualStructure of the 4-1BB/4-1BBL complex and distinct binding and functional properties of utomilumab and urelumab
P2860
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P2860
Galectin-9 controls the therapeutic activity of 4-1BB-targeting antibodies
description
2014 nî lūn-bûn
@nan
2014 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Galectin-9 controls the therapeutic activity of 4-1BB-targeting antibodies
@ast
Galectin-9 controls the therapeutic activity of 4-1BB-targeting antibodies
@en
Galectin-9 controls the therapeutic activity of 4-1BB-targeting antibodies
@nl
type
label
Galectin-9 controls the therapeutic activity of 4-1BB-targeting antibodies
@ast
Galectin-9 controls the therapeutic activity of 4-1BB-targeting antibodies
@en
Galectin-9 controls the therapeutic activity of 4-1BB-targeting antibodies
@nl
prefLabel
Galectin-9 controls the therapeutic activity of 4-1BB-targeting antibodies
@ast
Galectin-9 controls the therapeutic activity of 4-1BB-targeting antibodies
@en
Galectin-9 controls the therapeutic activity of 4-1BB-targeting antibodies
@nl
P2093
P2860
P50
P3181
P356
P1476
Galectin-9 controls the therapeutic activity of 4-1BB-targeting antibodies
@en
P2093
Amit Kumar Mehta
Dirk M Zajonc
Ivana Nemčovičová
Michael Croft
Mitsuomi Hirashima
Seung-Woo Lee
Toshiro Niki
P2860
P304
P3181
P356
10.1084/JEM.20132687
P407
P577
2014-06-30T00:00:00Z