Csk homologous kinase, a novel signaling molecule, directly associates with the activated ErbB-2 receptor in breast cancer cells and inhibits their proliferation
about
Csk homologous kinase (CHK) and ErbB-2 interactions are directly coupled with CHK negative growth regulatory function in breast cancerA comprehensive pathway map of epidermal growth factor receptor signalingPhosphotyrosine interactome of the ErbB-receptor kinase familyThe Csk homologous kinase associates with TrkA receptors and is involved in neurite outgrowth of PC12 cellsThe ErbB signaling network: receptor heterodimerization in development and cancerC-terminal Src kinase (CSK) and CSK-homologous kinase (CHK)--endogenous negative regulators of Src-family protein kinases.Trastuzumab-induced recruitment of Csk-homologous kinase (CHK) to ErbB2 receptor is associated with ErbB2-Y1248 phosphorylation and ErbB2 degradation to mediate cell growth inhibition.Purification, crystallization, small-angle X-ray scattering and preliminary X-ray diffraction analysis of the SH2 domain of the Csk-homologous kinase.Expression and purification of Src-family kinases for solution NMR studies.Trifunctional antibody ertumaxomab: Non-immunological effects on Her2 receptor activity and downstream signalingFunctional selectivity of EGF family peptide growth factors: implications for cancer.Functional analysis of Csk and CHK kinases in breast cancer cells.A genetic screen for modifiers of the lats tumor suppressor gene identifies C-terminal Src kinase as a regulator of cell proliferation in Drosophila.ErbB Receptors and Cancer.MATK (CSK homologous kinase) binds phosphorylated ERBB2
P2860
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P2860
Csk homologous kinase, a novel signaling molecule, directly associates with the activated ErbB-2 receptor in breast cancer cells and inhibits their proliferation
description
1998 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 1998
@ast
im Februar 1998 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1998/02/13)
@sk
vědecký článek publikovaný v roce 1998
@cs
wetenschappelijk artikel (gepubliceerd op 1998/02/13)
@nl
наукова стаття, опублікована в лютому 1998
@uk
name
Csk homologous kinase, a novel ...... d inhibits their proliferation
@ast
Csk homologous kinase, a novel ...... d inhibits their proliferation
@en
Csk homologous kinase, a novel ...... d inhibits their proliferation
@nl
type
label
Csk homologous kinase, a novel ...... d inhibits their proliferation
@ast
Csk homologous kinase, a novel ...... d inhibits their proliferation
@en
Csk homologous kinase, a novel ...... d inhibits their proliferation
@nl
prefLabel
Csk homologous kinase, a novel ...... d inhibits their proliferation
@ast
Csk homologous kinase, a novel ...... d inhibits their proliferation
@en
Csk homologous kinase, a novel ...... d inhibits their proliferation
@nl
P2093
P2860
P356
P1476
Csk homologous kinase, a novel ...... d inhibits their proliferation
@en
P2093
P2860
P304
P356
10.1074/JBC.273.7.4065
P407
P577
1998-02-01T00:00:00Z