Nonhuman primate models of Alzheimer-like cerebral proteopathy
about
Neurodegenerative diseases: expanding the prion conceptDietary exposure to an environmental toxin triggers neurofibrillary tangles and amyloid deposits in the brainThe relationship between iron dyshomeostasis and amyloidogenesis in Alzheimer's disease: Two sides of the same coin.Age-related alterations of plasma glutathione and oxidation of redox potentials in chimpanzee (Pan troglodytes) and rhesus monkey (Macaca mulatta).Amyloid Beta1-42 and the Phoshorylated Tau Threonine 231 in Brains of Aged Cynomolgus Monkeys (Macaca fascicularis).Lessons from the analysis of nonhuman primates for understanding human aging and neurodegenerative diseasesAmyloid-β oligomers unveil a novel primate model of sporadic Alzheimer's disease.Analysis of synaptic gene expression in the neocortex of primates reveals evolutionary changes in glutamatergic neurotransmissionExogenous seeding of cerebral β-amyloid deposition in βAPP-transgenic rats.The presence of Aβ seeds, and not age per se, is critical to the initiation of Aβ deposition in the brainCorruption and spread of pathogenic proteins in neurodegenerative diseases.Contributions of Nonhuman Primates to Research on Aging.Cognitive and motor aging in female chimpanzees.Cerebral amyloid angiopathy in an aged sooty mangabey (Cercocebus atys).Tau pathology in aged cynomolgus monkeys is progressive supranuclear palsy/corticobasal degeneration- but not Alzheimer disease-like -Ultrastructural mapping of tau by EDX.Infrastructure and resources for an aging population: embracing complexity in translational research.Context dependence of protein misfolding and structural strains in neurodegenerative diseases.Translation of Pre-Clinical Studies into Successful Clinical Trials for Alzheimer's Disease: What are the Roadblocks and How Can They Be Overcome?Behind the curtain of tauopathy: a show of multiple players orchestrating tau toxicity.Propagation of Aß pathology: hypotheses, discoveries, and yet unresolved questions from experimental and human brain studies.Non human primate models for Alzheimer's disease-related research and drug discovery.Overcoming translational barriers impeding development of Alzheimer's disease modifying therapies.Bridging the gap: large animal models in neurodegenerative research.The Prion-Like Properties of Amyloid-β Assemblies: Implications for Alzheimer's Disease.Alzheimer's disease: experimental models and reality.The Exceptional Vulnerability of Humans to Alzheimer's Disease.p53 isoforms regulate astrocyte-mediated neuroprotection and neurodegeneration.Comparative pathobiology of β-amyloid and the unique susceptibility of humans to Alzheimer's diseaseAmyloid-Related Imaging Abnormalities in an Aged Squirrel Monkey with Cerebral Amyloid Angiopathy.Human Striatal Dopaminergic and Regional Serotonergic Synaptic Degeneration with Lewy Body Disease and Inheritance of APOE ε4.A potential function for neuronal exosomes: sequestering intracerebral amyloid-β peptide.Upregulation of Aβ42 in the Brain and Bodily Fluids of Rhesus Monkeys with Aging.DNA damage in the oligodendrocyte lineage and its role in brain aging.Systems Pharmacology Analysis of the Amyloid Cascade after β-Secretase Inhibition Enables the Identification of an Aβ42 Oligomer Pool.Neurodegenerative disease biomarkers Aβ1-40, Aβ1-42, tau, and p-tau181 in the vervet monkey cerebrospinal fluid: Relation to normal aging, genetic influences, and cerebral amyloid angiopathy.
P2860
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P2860
Nonhuman primate models of Alzheimer-like cerebral proteopathy
description
2012 թուականին հրատարակուած գիտական յօդուած
@hyw
2012 թվականին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2012
@ast
im Januar 2012 veröffentlichter wissenschaftlicher Artikel
@de
scientific article (publication date: 2012)
@en
vedecký článok (publikovaný 2012)
@sk
vědecký článek publikovaný v roce 2012
@cs
wetenschappelijk artikel (gepubliceerd in 2012)
@nl
наукова стаття, опублікована у 2012
@uk
مقالة علمية (نشرت عام 2012)
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name
Nonhuman primate models of Alzheimer-like cerebral proteopathy
@ast
Nonhuman primate models of Alzheimer-like cerebral proteopathy
@en
Nonhuman primate models of Alzheimer-like cerebral proteopathy
@nl
type
label
Nonhuman primate models of Alzheimer-like cerebral proteopathy
@ast
Nonhuman primate models of Alzheimer-like cerebral proteopathy
@en
Nonhuman primate models of Alzheimer-like cerebral proteopathy
@nl
prefLabel
Nonhuman primate models of Alzheimer-like cerebral proteopathy
@ast
Nonhuman primate models of Alzheimer-like cerebral proteopathy
@en
Nonhuman primate models of Alzheimer-like cerebral proteopathy
@nl
P2860
P3181
P1476
Nonhuman primate models of Alzheimer-like cerebral proteopathy
@en
P2093
Amarallys Cintron
Eric Heuer
P2860
P304
P3181
P356
10.2174/138161212799315885
P407
P577
2012-01-01T00:00:00Z