Dasatinib as a bone-modifying agent: anabolic and anti-resorptive effects
about
Tyrosine kinase inhibitors and mesenchymal stromal cells: effects on self-renewal, commitment and functionsReceptor tyrosine kinases: Characterisation, mechanism of action and therapeutic interests for bone cancersNovel Phenotypic Outcomes Identified for a Public Collection of Approved Drugs from a Publicly Accessible Panel of AssaysA randomized phase II study of cediranib alone versus cediranib in combination with dasatinib in docetaxel resistant, castration resistant prostate cancer patients.The Src family kinase inhibitor dasatinib delays pain-related behaviour and conserves bone in a rat model of cancer-induced bone pain.Dissecting the role of bone marrow stromal cells on bone metastases.Multiple myeloma mesenchymal stromal cells: Contribution to myeloma bone disease and therapeuticsDynamic interplay between bone and multiple myeloma: emerging roles of the osteoblastP2X7 Receptor Function in Bone-Related Cancer.The epoxyketone-based proteasome inhibitors carfilzomib and orally bioavailable oprozomib have anti-resorptive and bone-anabolic activity in addition to anti-myeloma effects.Systematic screen with kinases inhibitors reveals kinases play distinct roles in growth of osteoprogenitor cellsAdverse skeletal effects of drugs - beyond Glucocorticoids.Monitoring Cell-surface N-Glycoproteome Dynamics by Quantitative Proteomics Reveals Mechanistic Insights into Macrophage Differentiation.Molecular mechanisms, current management and next generation therapy in myeloma bone disease.Current trends in bone tissue engineering.Dasatinib inhibits mammary tumour development in a genetically engineered mouse model.Multiparameter Analysis of Off-Target Effects of Dasatinib on Bone Homeostasis in Patients With Newly Diagnosed Chronic Myelogenous Leukemia.Transcriptomic profile induced in bone marrow mesenchymal stromal cells after interaction with multiple myeloma cells: implications in myeloma progression and myeloma bone disease.The tyrosine kinase inhibitor GNF-2 suppresses osteoclast formation and activity.NS-018 reduces myeloma cell proliferation and suppresses osteolysis through inhibition of the JAK2 and Src signaling pathways.Therapeutic effects of the novel subtype-selective histone deacetylase inhibitor chidamide on myeloma-associated bone disease
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P2860
Dasatinib as a bone-modifying agent: anabolic and anti-resorptive effects
description
2012 թուականին հրատարակուած գիտական յօդուած
@hyw
2012 թվականին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique PLoS ONE
@fr
artículu científicu espublizáu en 2012
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im Januar 2012 veröffentlichter wissenschaftlicher Artikel
@de
scientific article (publication date: 2012)
@en
vedecký článok (publikovaný 2012)
@sk
vědecký článek publikovaný v roce 2012
@cs
wetenschappelijk artikel (gepubliceerd in 2012)
@nl
наукова стаття, опублікована у 2012
@uk
name
Dasatinib as a bone-modifying agent: anabolic and anti-resorptive effects
@ast
Dasatinib as a bone-modifying agent: anabolic and anti-resorptive effects
@en
Dasatinib as a bone-modifying agent: anabolic and anti-resorptive effects
@nl
type
label
Dasatinib as a bone-modifying agent: anabolic and anti-resorptive effects
@ast
Dasatinib as a bone-modifying agent: anabolic and anti-resorptive effects
@en
Dasatinib as a bone-modifying agent: anabolic and anti-resorptive effects
@nl
prefLabel
Dasatinib as a bone-modifying agent: anabolic and anti-resorptive effects
@ast
Dasatinib as a bone-modifying agent: anabolic and anti-resorptive effects
@en
Dasatinib as a bone-modifying agent: anabolic and anti-resorptive effects
@nl
P2093
P2860
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P1433
P1476
Dasatinib as a bone-modifying agent: anabolic and anti-resorptive effects
@en
P2093
Antonio Garcia-Gomez
Atanasio Pandiella
Carlos Santamaria
Edvan Crusoe
Francis Y Lee
Juan F Blanco
Pilar Hernández-Campo
Rosa M Fisac-Herrero
Teresa Hernández-Iglesias
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P304
P356
10.1371/JOURNAL.PONE.0034914
P407
P577
2012-04-23T00:00:00Z