Co-immunization with multimeric scaffolds and DNA rapidly induces potent autologous HIV-1 neutralizing antibodies and CD8+ T cells
about
DNA and protein co-immunization improves the magnitude and longevity of humoral immune responses in macaquesHumoral immunity induced by mucosal and/or systemic SIV-specific vaccine platforms suggests novel combinatorial approaches for enhancing responses.Comprehensive analysis of contributions from protein conformational stability and major histocompatibility complex class II-peptide binding affinity to CD4+ epitope immunogenicity in HIV-1 envelope glycoprotein.Elicitation of HIV-1-neutralizing antibodies against the CD4-binding site.Vaccine delivery to the oral cavity using coated microneedles induces systemic and mucosal immunityEvaluation of protection induced by a dengue virus serotype 2 envelope domain III protein scaffold/DNA vaccine in non-human primates.Envelope variants circulating as initial neutralization breadth developed in two HIV-infected subjects stimulate multiclade neutralizing antibodies in rabbits.Multimeric scaffolds displaying the HIV-1 envelope MPER induce MPER-specific antibodies and cross-neutralizing antibodies when co-immunized with gp160 DNAHIV DNA Vaccine: Stepwise Improvements Make a Difference.Novel antigen delivery systems.Design and characterization of a peptide mimotope of the HIV-1 gp120 bridging sheetE2 multimeric scaffold for vaccine formulation: immune response by intranasal delivery and transcriptome profile of E2-pulsed dendritic cellsDelivery strategies for novel vaccine formulations.Biomimetic protein nanoparticles facilitate enhanced dendritic cell activation and cross-presentation.Improvement of antibody responses by HIV envelope DNA and protein co-immunization.Distinct Antigen Delivery Systems Induce Dendritic Cells' Divergent Transcriptional Response: New Insights from a Comparative and Reproducible Computational Analysis.Evaluation of a novel multi-immunogen vaccine strategy for targeting 4E10/10E8 neutralizing epitopes on HIV-1 gp41 membrane proximal external region.Single-cycle adenovirus vectors in the current vaccine landscape.Control of Heterologous Simian Immunodeficiency Virus SIV Infection by DNA and Protein Coimmunization Regimens Combined with Different Toll-Like-Receptor-4-Based Adjuvants in Macaques
P2860
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P2860
Co-immunization with multimeric scaffolds and DNA rapidly induces potent autologous HIV-1 neutralizing antibodies and CD8+ T cells
description
2012 nî lūn-bûn
@nan
2012 թուականին հրատարակուած գիտական յօդուած
@hyw
2012 թվականին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Co-immunization with multimeri ...... ng antibodies and CD8+ T cells
@ast
Co-immunization with multimeri ...... ng antibodies and CD8+ T cells
@en
Co-immunization with multimeri ...... ng antibodies and CD8+ T cells
@nl
type
label
Co-immunization with multimeri ...... ng antibodies and CD8+ T cells
@ast
Co-immunization with multimeri ...... ng antibodies and CD8+ T cells
@en
Co-immunization with multimeri ...... ng antibodies and CD8+ T cells
@nl
prefLabel
Co-immunization with multimeri ...... ng antibodies and CD8+ T cells
@ast
Co-immunization with multimeri ...... ng antibodies and CD8+ T cells
@en
Co-immunization with multimeri ...... ng antibodies and CD8+ T cells
@nl
P2093
P2860
P50
P3181
P1433
P1476
Co-immunization with multimeri ...... ng antibodies and CD8+ T cells
@en
P2093
Delphine Malherbe
Dina N Kovarik
Garrett Waagmeester
Maria Trovato
Nicole A Doria-Rose
Shelly J Krebs
Susan Barnett
William F Sutton
Zachary Brower
P2860
P304
P3181
P356
10.1371/JOURNAL.PONE.0031464
P407
P50
P577
2012-01-01T00:00:00Z