Gefitinib induces epidermal growth factor receptor dimers which alters the interaction characteristics with ¹²⁵I-EGF

Gefitinib induces epidermal growth factor receptor dimers which alters the interaction characteristics with ¹²⁵I-EGF

Item
http://www.wikidata.org/entity/Q28740473
Heptameric targeting ligands against EGFR and HER2 with high stability and avidity.The HER2-binding affibody molecule (Z(HER2∶342))₂ increases radiosensitivity in SKBR-3 cells.ATP binding to p97/VCP D1 domain regulates selective recruitment of adaptors to its proximal N-domain.Profiling epidermal growth factor receptor and heregulin receptor 3 heteromerization using receptor tyrosine kinase heteromer investigation technology.Imaging of CAIX-expressing xenografts in vivo using 99mTc-HEHEHE-ZCAIX:1 affibody moleculeDeciphering the stepwise binding mode of HRG1β to HER3 by surface plasmon resonance and interaction map.Tyrosine 370 phosphorylation of ATM positively regulates DNA damage response.Significant increase in hEGF uptake is correlated with formation of EGFR dimers induced by the EGFR tyrosine kinase inhibitor gefitinibResolving the EGF-EGFR interaction characteristics through a multiple-temperature, multiple-inhibitor, real-time interaction analysis approach.Liquid-phase electron microscopy of molecular drug response in breast cancer cells reveals irresponsive cell subpopulations related to lack of HER2 homodimers.Preclinical evaluation of radiolabelled nimotuzumab, a promising monoclonal antibody targeting the epidermal growth factor receptor.[99mTc(CO)3]+-(HE)3-ZIGF1R:4551, a new Affibody conjugate for visualization of insulin-like growth factor-1 receptor expression in malignant tumours.Real-time Characterization of Antibody Binding to Receptors on Living Immune Cells.Comparative evaluation of tumor targeting using the anti-HER2 ADAPT scaffold protein labeled at the C-terminus with indium-111 or technetium-99m.Evaluation of HER2-specific peptide ligand for its employment as radiolabeled imaging probe.In vitro evaluation of concentration, labeling effectiveness and stability for 131 I-labeled radioimmunoassay ligand using real-time detection technology.Relationship between the agonist activity of synthetic ligands of TRAIL-R2 and their cell surface binding modes.
P2860

Gefitinib induces epidermal growth factor receptor dimers which alters the interaction characteristics with ¹²⁵I-EGF

Item
http://www.wikidata.org/entity/Q28740473
description
2011 nî lūn-bûn
@nan
2011 թուականին հրատարակուած գիտական յօդուած
@hyw
2011 թվականին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Gefitinib induces epidermal gr ...... characteristics with ¹²⁵I-EGF
@ast
Gefitinib induces epidermal gr ...... characteristics with ¹²⁵I-EGF
@en
Gefitinib induces epidermal gr ...... characteristics with ¹²⁵I-EGF
@nl
type
label
Gefitinib induces epidermal gr ...... characteristics with ¹²⁵I-EGF
@ast
Gefitinib induces epidermal gr ...... characteristics with ¹²⁵I-EGF
@en
Gefitinib induces epidermal gr ...... characteristics with ¹²⁵I-EGF
@nl
prefLabel
Gefitinib induces epidermal gr ...... characteristics with ¹²⁵I-EGF
@ast
Gefitinib induces epidermal gr ...... characteristics with ¹²⁵I-EGF
@en
Gefitinib induces epidermal gr ...... characteristics with ¹²⁵I-EGF
@nl
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P1476
P2093
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Gefitinib induces epidermal gr ...... characteristics with ¹²⁵I-EGF
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P2093
P2860
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P31
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10.1371/JOURNAL.PONE.0024739
P407
P433
P478
P50
P577
P5875
P698
P932