Evolutionary optimization of speed and accuracy of decoding on the ribosome
about
Reorganization of an intersubunit bridge induced by disparate 16S ribosomal ambiguity mutations mimics an EF-Tu-bound stateReview: Translational GTPasesMice fed rapamycin have an increase in lifespan associated with major changes in the liver transcriptomeDeducing the kinetics of protein synthesis in vivo from the transition rates measured in vitroThe chemical origins of life and its early evolution: an introductionStructural insights into the translational infidelity mechanism.Labeled EF-Tus for rapid kinetic studies of pretranslocation complex formationAnother look at mutations in ribosomal protein S4 lends strong support to the domain closure modelProtein Synthesis in E. coli: Dependence of Codon-Specific Elongation on tRNA Concentration and Codon Usage.Models of buffering of dosage imbalances in protein complexes.Suppression of premature termination codons as a therapeutic approach.Exceptionally large entropy contributions enable the high rates of GTP hydrolysis on the ribosome.EF-Tu dynamics during pre-translocation complex formation: EF-Tu·GDP exits the ribosome via two different pathways.Novel base-pairing interactions at the tRNA wobble position crucial for accurate reading of the genetic code.Ribosomal ambiguity made less ambiguousBiomolecular dynamics: order-disorder transitions and energy landscapesAnalysis of Translation Elongation Dynamics in the Context of an Escherichia coli CellMonitoring translation with modified mRNAs strategically labeled with isomorphic fluorescent guanosine mimetics.An integrated, structure- and energy-based view of the genetic code.Functional role of methylation of G518 of the 16S rRNA 530 loop by GidB in Mycobacterium tuberculosis.Diversity of human tRNA genes from the 1000-genomes project.Therapeutics based on stop codon readthrough.Recognition of Watson-Crick base pairs: constraints and limits due to geometric selection and tautomerism.Rarely at rest: RNA helicases and their busy contributions to RNA degradation, regulation and quality control.New structural insights into the decoding mechanism: translation infidelity via a G·U pair with Watson-Crick geometry.Emerging roles of tRNA in adaptive translation, signalling dynamics and disease.Modifying the maker: Oxygenases target ribosome biology.Targeting Nonsense Mutations in Diseases with Translational Read-Through-Inducing Drugs (TRIDs).Role of Proteome Physical Chemistry in Cell Behavior.Length-dependent translation initiation benefits the functional proteome of human cells.Function and origin of mistranslation in distinct cellular contexts.GTPases IF2 and EF-G bind GDP and the SRL RNA in a mutually exclusive manner.Trade-offs between tRNA abundance and mRNA secondary structure support smoothing of translation elongation rate.Real-Time Imaging Reveals Properties of Glutamate-Induced Arc/Arg 3.1 Translation in Neuronal Dendrites.The pathway to GTPase activation of elongation factor SelB on the ribosome.Optimization of high-throughput sequencing kinetics for determining enzymatic rate constants of thousands of RNA substrates.tRNA residues evolved to promote translational accuracy.The seed region of a small RNA drives the controlled destruction of the target mRNA by the endoribonuclease RNase E.Elucidating interplay of speed and accuracy in biological error correction.Stringent Nucleotide Recognition by the Ribosome at the Middle Codon Position.
P2860
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P2860
Evolutionary optimization of speed and accuracy of decoding on the ribosome
description
2011 nî lūn-bûn
@nan
2011 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Evolutionary optimization of speed and accuracy of decoding on the ribosome
@ast
Evolutionary optimization of speed and accuracy of decoding on the ribosome
@en
Evolutionary optimization of speed and accuracy of decoding on the ribosome
@nl
type
label
Evolutionary optimization of speed and accuracy of decoding on the ribosome
@ast
Evolutionary optimization of speed and accuracy of decoding on the ribosome
@en
Evolutionary optimization of speed and accuracy of decoding on the ribosome
@nl
prefLabel
Evolutionary optimization of speed and accuracy of decoding on the ribosome
@ast
Evolutionary optimization of speed and accuracy of decoding on the ribosome
@en
Evolutionary optimization of speed and accuracy of decoding on the ribosome
@nl
P2093
P2860
P3181
P356
P1476
Evolutionary optimization of speed and accuracy of decoding on the ribosome
@en
P2093
Corinna Pohl
Ingo Wohlgemuth
Joerg Mittelstaet
P2860
P304
P3181
P356
10.1098/RSTB.2011.0138
P407
P577
2011-10-27T00:00:00Z