Increased breadth and depth of cytotoxic T lymphocytes responses against HIV-1-B Nef by inclusion of epitope variant sequences
about
A human immune data-informed vaccine concept elicits strong and broad T-cell specificities associated with HIV-1 control in mice and macaques.Intra- and inter-clade cross-reactivity by HIV-1 Gag specific T-cells reveals exclusive and commonly targeted regions: implications for current vaccine trialsCD8 and CD4 epitope predictions in RV144: no strong evidence of a T-cell driven sieve effect in HIV-1 breakthrough sequences from trial participants.Autologous HIV-1 clade-B Nef peptides elicit increased frequency, breadth and function of CD8+ T-cells compared to consensus peptides.HIV-1 p24(gag) derived conserved element DNA vaccine increases the breadth of immune response in mice.Nef-specific CD8+ T cell responses contribute to HIV-1 immune control.Evaluating potential T-cell epitope peptides for detecting HIV-specific T cell responses in a highly diverse HIV-1 epidemic from Cameroon.A computational method for identification of vaccine targets from protein regions of conserved human leukocyte antigen bindingConservation analysis of dengue virus T-cell epitope-based vaccine candidates using Peptide block entropy.Correlates of protective cellular immunity revealed by analysis of population-level immune escape pathways in HIV-1.Current status and perspectives of plant-based candidate vaccines against the human immunodeficiency virus (HIV).A study of vaccine-induced immune pressure on breakthrough infections in the Phambili phase 2b HIV-1 vaccine efficacy trial.The APPEESFRS Peptide, Restricted by the HLA-B*35:01 Molecule, and the APPEESFRF Variant Derived from an Autologous HIV-1 Strain Induces Polyfunctional Responses in CD8+ T Cells.Cross-reactive microbial peptides can modulate HIV-specific CD8+ T cell responses.
P2860
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P2860
Increased breadth and depth of cytotoxic T lymphocytes responses against HIV-1-B Nef by inclusion of epitope variant sequences
description
2011 nî lūn-bûn
@nan
2011 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մարտին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Increased breadth and depth of ...... n of epitope variant sequences
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Increased breadth and depth of ...... n of epitope variant sequences
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Increased breadth and depth of ...... n of epitope variant sequences
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Increased breadth and depth of ...... n of epitope variant sequences
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Increased breadth and depth of ...... n of epitope variant sequences
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Increased breadth and depth of ...... n of epitope variant sequences
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Increased breadth and depth of ...... n of epitope variant sequences
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Increased breadth and depth of ...... n of epitope variant sequences
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Increased breadth and depth of ...... n of epitope variant sequences
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David C Nickle
David E Heckerman
James I Mullins
Morgane Rolland
Nebojsa Jojic
Nicole Frahm
Todd M Allen
Wenjie Deng
P2860
P304
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10.1371/JOURNAL.PONE.0017969
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2011-03-28T00:00:00Z