Multiparameter RNA and codon optimization: a standardized tool to assess and enhance autologous mammalian gene expression - Wikidata - awgldk - TriplyDB

Multiparameter RNA and codon optimization: a standardized tool to assess and enhance autologous mammalian gene expression

Multiparameter RNA and codon optimization: a standardized tool to assess and enhance autologous mammalian gene expression

http://www.wikidata.org/entity/Q28742249

about

The KSHV RNA regulator ORF57: target specificity and its role in the viral life cycle Decoding mechanisms by which silent codon changes influence protein biogenesis and function Recombinant messenger RNA technology and its application in cancer immunotherapy, transcript replacement therapies, pluripotent stem cell induction, and beyond Messenger RNA-based vaccines: progress, challenges, applications Engineering Translation in Mammalian Cell Factories to Increase Protein Yield: The Unexpected Use of Long Non-Coding SINEUP RNAs An albumin-derived peptide scaffold capable of binding and catalysis Recombinant production of the amino terminal cytoplasmic region of dengue virus non-structural protein 4A for structural studies Expression and characterization of a codon-optimized blood coagulation factor VIII.Treatment of diabetes and long-term survival after insulin and glucokinase gene therapy.Complete biosynthesis of opioids in yeast A novel Sin Nombre virus DNA vaccine and its inclusion in a candidate pan-hantavirus vaccine against hantavirus pulmonary syndrome (HPS) and hemorrhagic fever with renal syndrome (HFRS).Low-Dose Gene Therapy for Murine PKU Using Episomal Naked DNA Vectors Expressing PAH from Its Endogenous Liver Promoter The notorious R.N.A. in the spotlight - drug or target for the treatment of disease A critical analysis of codon optimization in human therapeutics.C.U.R.R.F. (Codon Usage regarding Restriction Finder): a free Java(®)-based tool to detect potential restriction sites in both coding and non-coding DNA sequences.Genomic mining of prokaryotic repressors for orthogonal logic gates.Transient B cell depletion or improved transgene expression by codon optimization promote tolerance to factor VIII in gene therapy.Embedding permanent watermarks in synthetic genes.Systematic transfer of prokaryotic sensors and circuits to mammalian cells Establishment of stably transfected cells constitutively expressing the full-length and truncated antigenic proteins of two genetically distinct mink astroviruses.Codon optimization of the human papillomavirus E7 oncogene induces a CD8+ T cell response to a cryptic epitope not harbored by wild-type E7 Human involucrin promoter mediates repression-resistant and compartment-specific LEKTI expression AAV-mediated gene transfer in the perinatal period results in expression of FVII at levels that protect against fatal spontaneous hemorrhage.Vector Design for Improved DNA Vaccine Efficacy, Safety and Production.UU/UA dinucleotide frequency reduction in coding regions results in increased mRNA stability and protein expression.Construction and nonclinical testing of a Puumala virus synthetic M gene-based DNA vaccine.Interaction of members of the heat shock protein-70 family with the macrophage mannose receptor.Engineering Factor Viii for Hemophilia Gene Therapy.Optimizing plant transporter expression in Xenopus oocytes.Design of an Optimized Wilms' Tumor 1 (WT1) mRNA Construct for Enhanced WT1 Expression and Improved Immunogenicity In Vitro and In Vivo Optimized inducible shRNA and CRISPR/Cas9 platforms for in vitro studies of human development using hPSCs.GeneOptimizer program-assisted cDNA reengineering enhances sRAGE autologous expression in Chinese hamster ovary cells.Manipulating the genetic code for membrane protein production: what have we learnt so far?mRNA: From a chemical blueprint for protein production to an off-the-shelf therapeutic.Gene therapy for retinal disease The ReNAissanCe of mRNA-based cancer therapy.Production of lycopene in the non-carotenoid-producing yeast Yarrowia lipolytica.CpG domains downstream of TSSs promote high levels of gene expression.Codon Optimization Leads to Functional Impairment of RD114-TR Envelope Glycoprotein.Synthetic gene design-The rationale for codon optimization and implications for molecular pharming in plants.

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Multiparameter RNA and codon optimization: a standardized tool to assess and enhance autologous mammalian gene expression

http://www.wikidata.org/entity/Q28742249

description

2011 nî lūn-bûn

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2011 թուականի Մարտին հրատարակուած գիտական յօդուած

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2011 թվականի մարտին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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Multiparameter RNA and codon o ...... gous mammalian gene expression

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Multiparameter RNA and codon o ...... gous mammalian gene expression

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Anne Spriestersbach

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Asli Petra Bauer

http://www.w3.org/2001/XMLSchema#string

Barbara Maertens

http://www.w3.org/2001/XMLSchema#string

Christine Ludwig

http://www.w3.org/2001/XMLSchema#string

Frank Schäfer

http://www.w3.org/2001/XMLSchema#string

Marcus Graf

http://www.w3.org/2001/XMLSchema#string

Michael Liss

http://www.w3.org/2001/XMLSchema#string

Peter Hahn

http://www.w3.org/2001/XMLSchema#string

Ralf Wagner

http://www.w3.org/2001/XMLSchema#string

Stephan Fath

http://www.w3.org/2001/XMLSchema#string

P2860

Design parameters to control synthetic gene expression in Escherichia coli

Expression of human nPTB is limited by extreme suboptimal codon content

The codon Adaptation Index--a measure of directional synonymous codon usage bias, and its potential applications

Increased immune response elicited by DNA vaccination with a synthetic gp120 sequence with optimized codon usage

Real-time RT-PCR analysis of mRNA decay: half-life of Beta-actin mRNA in human leukemia CCRF-CEM and Nalm-6 cell lines.

CpG content affects gene silencing in mice: evidence from novel transgenes

A new mathematical model for relative quantification in real-time RT-PCR

Tissue-specific differences in human transfer RNA expression

Codon preferences in free-living microorganisms

High guanine and cytosine content increases mRNA levels in mammalian cells

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e17596

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2763298

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10.1371/JOURNAL.PONE.0017596

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21408612

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