Overexpression of Kpnβ1 and Kpnα2 importin proteins in cancer derives from deregulated E2F activity

Overexpression of Kpnβ1 and Kpnα2 importin proteins in cancer derives from deregulated E2F activity

Item
http://www.wikidata.org/entity/Q28742539
Identification of potential new treatment response markers and therapeutic targets using a Gaussian process-based method in lapatinib insensitive breast cancer models.Pleomorphic adenoma gene 1 mediates the role of karyopherin alpha 2 and has prognostic significance in hepatocellular carcinoma.Subcellular proteomics reveals a role for nucleo-cytoplasmic trafficking at the DNA replication origin activation checkpointKaryopherin alpha2 is essential for rRNA transcription and protein synthesis in proliferative keratinocytesDiversification of importin-α isoforms in cellular trafficking and disease statesTargeting nuclear transporters in cancer: Diagnostic, prognostic and therapeutic potential.MiR-26b/KPNA2 axis inhibits epithelial ovarian carcinoma proliferation and metastasis through downregulating OCT4.mTOR regulates proteasomal degradation and Dp1/E2F1- mediated transcription of KPNA2 in lung cancer cellsBiological significance of the importin-β family-dependent nucleocytoplasmic transport pathways.Upregulation of KPNβ1 in gastric cancer cell promotes tumor cell proliferation and predicts poor prognosis.Nuclear karyopherin-α2 expression in primary lesions and metastatic lymph nodes was associated with poor prognosis and progression in gastric cancer.The role of KPNβ1 in neuro-oncology.Investigation of RIP140 and LCoR as independent markers for poor prognosis in cervical cancer.Suppression of Kpnβ1 expression inhibits human breast cancer cell proliferation by abrogating nuclear transport of Her2.Defining the Akt1 interactome and its role in regulating the cell cycle.High expression of karyopherin-α2 and stathmin 1 is associated with proliferation potency and transformation in the bile duct and gall bladder epithelia in the cases of pancreaticobiliary maljunction.KPNB1 inhibition disrupts proteostasis and triggers unfolded protein response-mediated apoptosis in glioblastoma cells.
P2860

Overexpression of Kpnβ1 and Kpnα2 importin proteins in cancer derives from deregulated E2F activity

Item
http://www.wikidata.org/entity/Q28742539
description
2011 nî lūn-bûn
@nan
2011 թուականին հրատարակուած գիտական յօդուած
@hyw
2011 թվականին հրատարակված գիտական հոդված
@hy
2011年の論文
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2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
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name
Overexpression of Kpnβ1 and Kp ...... from deregulated E2F activity
@ast
Overexpression of Kpnβ1 and Kp ...... from deregulated E2F activity
@en
Overexpression of Kpnβ1 and Kp ...... from deregulated E2F activity
@nl
type
label
Overexpression of Kpnβ1 and Kp ...... from deregulated E2F activity
@ast
Overexpression of Kpnβ1 and Kp ...... from deregulated E2F activity
@en
Overexpression of Kpnβ1 and Kp ...... from deregulated E2F activity
@nl
prefLabel
Overexpression of Kpnβ1 and Kp ...... from deregulated E2F activity
@ast
Overexpression of Kpnβ1 and Kp ...... from deregulated E2F activity
@en
Overexpression of Kpnβ1 and Kp ...... from deregulated E2F activity
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P921
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P1433
P1476
Overexpression of Kpnβ1 and Kp ...... from deregulated E2F activity
@en
P2093
P2860
P304
P31
P356
10.1371/JOURNAL.PONE.0027723
P407
P433
P478
P577
P5875
P698
P921
P932