Generation of human antigen-specific monoclonal IgM antibodies using vaccinated "human immune system" mice - Wikidata - awgldk - TriplyDB

Generation of human antigen-specific monoclonal IgM antibodies using vaccinated "human immune system" mice

Generation of human antigen-specific monoclonal IgM antibodies using vaccinated "human immune system" mice

http://www.wikidata.org/entity/Q28749033

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Vaccines: from empirical development to rational design New generation humanized mice for virus research: comparative aspects and future prospects High-affinity IgG antibodies develop naturally in Ig-knockout rats carrying germline human IgH/Igκ/Igλ loci bearing the rat CH region Creation of an immunodeficient HLA-transgenic mouse (HUMAMICE) and functional validation of human immunity after transfer of HLA-matched human cells.GM-CSF and IL-4 stimulate antibody responses in humanized mice by promoting T, B, and dendritic cell maturation.Mimicking the germinal center reaction in hybridoma cells to isolate temperature-selective anti-PEG antibodies.Co-transplantation of human hematopoietic stem cells and human breast cancer cells in NSG mice: a novel approach to generate tumor cell specific human antibodies.Antibody repertoires in humanized NOD-scid-IL2Rγ(null) mice and human B cells reveals human-like diversification and tolerance checkpoints in the mouse Low immunogenicity of neural progenitor cells differentiated from induced pluripotent stem cells derived from less immunogenic somatic cells.A novel and effective cancer immunotherapy mouse model using antigen-specific B cells selected in vitro Transgenic expression of human signal regulatory protein alpha in Rag2-/-gamma(c)-/- mice improves engraftment of human hematopoietic cells in humanized mice.The utility of the new generation of humanized mice to study HIV-1 infection: transmission, prevention, pathogenesis, and treatment.New challenges in modern vaccinology Discovery of high affinity anti-ricin antibodies by B cell receptor sequencing and by yeast display of combinatorial VH:VL libraries from immunized animals.Human B-cell ontogeny in humanized NOD/SCID γc(null) mice generates a diverse yet auto/poly- and HIV-1-reactive antibody repertoire.Activation of Innate and Adaptive Immunity by a Recombinant Human Cytomegalovirus Strain Expressing an NKG2D Ligand Increasing hematopoietic stem cell yield to develop mice with human immune systems.B-cell repertoire dynamics after sequential hepatitis B vaccination and evidence for cross-reactive B-cell activation.Humanized mouse models of HIV infection Humanized mice for immune system investigation: progress, promise and challenges Humanized mouse G6 anti-idiotypic monoclonal antibody has therapeutic potential against IGHV1-69 germline gene-based B-CLL.Humoral immunity in humanized mice: a work in progress.Improved B cell development in humanized NOD-scid IL2Rγnull mice transgenically expressing human stem cell factor, granulocyte-macrophage colony-stimulating factor and interleukin-3 A novel humanized mouse model with significant improvement of class-switched, antigen-specific antibody production Human immune responses and potential for vaccine assessment in humanized mice.Infectious diseases in humanized mice.Humanized NOG mice as a model for tuberculosis vaccine-induced immunity: a comparative analysis with the mouse and guinea pig models of tuberculosis.Human responses against HER-2-positive cancer cells in human immune system-engrafted mice.Enhanced humoral and HLA-A2-restricted dengue virus-specific T-cell responses in humanized BLT NSG mice.Sustained Engraftment of Cryopreserved Human Bone Marrow CD34(+) Cells in Young Adult NSG Mice.A doxycycline-dependent human immunodeficiency virus type 1 replicates in vivo without inducing CD4+ T-cell depletion.Humoral immune responses in humanized BLT mice immunized with West Nile virus and HIV-1 envelope proteins are largely mediated via human CD5+ B cells.New models of human immunity.

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Generation of human antigen-specific monoclonal IgM antibodies using vaccinated "human immune system" mice

http://www.wikidata.org/entity/Q28749033

description

2010 nî lūn-bûn

@nan

2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Generation of human antigen-sp ...... ted "human immune system" mice

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Generation of human antigen-sp ...... ted "human immune system" mice

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Generation of human antigen-sp ...... ted "human immune system" mice

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Generation of human antigen-sp ...... ted "human immune system" mice

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JOURNAL.PONE.0013137

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Generation of human antigen-sp ...... ted "human immune system" mice

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Annick Lim

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Carlos A Guzman

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Caroline M M van Geelen

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Etsuko Yasuda

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Heiner Wedemeyer

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Hergen Spits

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Kees Weijer

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Michael Ott

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Miriam Noerder

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Nicholas D Huntington

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P2860

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Human immunoglobulin M memory B cells controlling Streptococcus pneumoniae infections are generated in the spleen

Continuous cultures of fused cells secreting antibody of predefined specificity

Lentiviral vector delivery of human interleukin-7 (hIL-7) to human immune system (HIS) mice expands T lymphocyte populations

The BCL-6 proto-oncogene controls germinal-centre formation and Th2-type inflammation

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A senescence rescue screen identifies BCL6 as an inhibitor of anti-proliferative p19(ARF)-p53 signaling.

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Human lymphoid and myeloid cell development in NOD/LtSz-scid IL2R gamma null mice engrafted with mobilized human hemopoietic stem cells.

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10

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5

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Nicolas Legrand

James P Di Santo

Ferenc A Scheeren

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2010-10-04T00:00:00Z

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47460160

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20957227

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