Fibroblasts from naked mole-rats are resistant to multiple forms of cell injury, but sensitive to peroxide, ultraviolet light, and endoplasmic reticulum stress
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RNA sequencing reveals differential expression of mitochondrial and oxidation reduction genes in the long-lived naked mole-rat when compared to miceForever young: mechanisms of natural anoxia tolerance and potential links to longevityUnraveling the message: insights into comparative genomics of the naked mole-ratFamily Wide Molecular Adaptations to Underground Life in African Mole-Rats Revealed by Phylogenomic Analysis.Stress profiling of longevity mutants identifies Afg3 as a mitochondrial determinant of cytoplasmic mRNA translation and agingTesting the oxidative stress hypothesis of aging in primate fibroblasts: is there a correlation between species longevity and cellular ROS production?Comparative cellular biogerontology: primer and prospectusCell stress and aging: new emphasis on multiplex resistance mechanismsTransmission of mutant phenotypes from ES cells to adult mice.Update on the oxidative stress theory of aging: does oxidative stress play a role in aging or healthy aging?Antioxidant enzyme activities are not broadly correlated with longevity in 14 vertebrate endotherm speciesAnd the beat goes on: maintained cardiovascular function during aging in the longest-lived rodent, the naked mole-rat.The naked mole-rat response to oxidative stress: just deal with it.Screening for stress-resistance mutations in the mouseCell resilience in species life spans: a link to inflammation?Early life growth hormone treatment shortens longevity and decreases cellular stress resistance in long-lived mutant miceA cellular perspective on conformational disease: the role of genetic background and proteostasis networks.Fibroblasts from long-lived rodent species exclude cadmium.Free radical production, antioxidant capacity, and oxidative stress response signatures in fibroblasts from Lewis dwarf rats: effects of life span-extending peripubertal GH treatment.Elevated ATF4 function in fibroblasts and liver of slow-aging mutant mice.Heightened induction of proapoptotic signals in response to endoplasmic reticulum stress in primary fibroblasts from a mouse model of longevityRegulation of Nrf2 signaling and longevity in naturally long-lived rodents.Comparative DNA damage and repair in echinoderm coelomocytes exposed to genotoxicantsStress resistance in the naked mole-rat: the bare essentials - a mini-review.Getting to the heart of the matter: age-related changes in diastolic heart function in the longest-lived rodent, the naked mole rat.Protein homeostasis in models of aging and age-related conformational disease.Resistance to genotoxic stresses in Arctica islandica, the longest living noncolonial animal: is extreme longevity associated with a multistress resistance phenotype?A cytosolic protein factor from the naked mole-rat activates proteasomes of other species and protects these from inhibition.Resistance to experimental tumorigenesis in cells of a long-lived mammal, the naked mole-rat (Heterocephalus glaber).Protein stability and resistance to oxidative stress are determinants of longevity in the longest-living rodent, the naked mole-rat.Lack of methionine sulfoxide reductase A in mice increases sensitivity to oxidative stress but does not diminish life span.Walking the oxidative stress tightrope: a perspective from the naked mole-rat, the longest-living rodentPhysiological underpinnings associated with differences in pace of life and metabolic rate in north temperate and neotropical birds.Unraveling the gut microbiome of the long-lived naked mole-rat.Proteostasis and ageing: insights from long-lived mutant mice.Cellular metabolic rate is influenced by life-history traits in tropical and temperate birds.Fibroblasts from long-lived mutant mice show diminished ERK1/2 phosphorylation but exaggerated induction of immediate early genes.The oxidative stress theory of aging: embattled or invincible? Insights from non-traditional model organisms.Fibroblasts from long-lived bird species are resistant to multiple forms of stress.The long lifespan of two bat species is correlated with resistance to protein oxidation and enhanced protein homeostasis.
P2860
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P2860
Fibroblasts from naked mole-rats are resistant to multiple forms of cell injury, but sensitive to peroxide, ultraviolet light, and endoplasmic reticulum stress
description
2008 nî lūn-bûn
@nan
2008 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի մարտին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Fibroblasts from naked mole-ra ...... d endoplasmic reticulum stress
@ast
Fibroblasts from naked mole-ra ...... d endoplasmic reticulum stress
@en
Fibroblasts from naked mole-ra ...... d endoplasmic reticulum stress
@nl
type
label
Fibroblasts from naked mole-ra ...... d endoplasmic reticulum stress
@ast
Fibroblasts from naked mole-ra ...... d endoplasmic reticulum stress
@en
Fibroblasts from naked mole-ra ...... d endoplasmic reticulum stress
@nl
prefLabel
Fibroblasts from naked mole-ra ...... d endoplasmic reticulum stress
@ast
Fibroblasts from naked mole-ra ...... d endoplasmic reticulum stress
@en
Fibroblasts from naked mole-ra ...... d endoplasmic reticulum stress
@nl
P2093
P2860
P3181
P356
P1476
Fibroblasts from naked mole-ra ...... d endoplasmic reticulum stress
@en
P2093
Adam B Salmon
Amir A Sadighi Akha
Richard A Miller
Rochelle Buffenstein
P2860
P304
P3181
P356
10.1093/GERONA/63.3.232
P407
P577
2008-03-01T00:00:00Z