Immune protection of nonhuman primates against Ebola virus with single low-dose adenovirus vectors encoding modified GPs - Wikidata - awgldk - TriplyDB

Immune protection of nonhuman primates against Ebola virus with single low-dose adenovirus vectors encoding modified GPs

Immune protection of nonhuman primates against Ebola virus with single low-dose adenovirus vectors encoding modified GPs

http://www.wikidata.org/entity/Q28768041

about

Recombinant vesicular stomatitis virus vaccine vectors expressing filovirus glycoproteins lack neurovirulence in nonhuman primates Nasal delivery of an adenovirus-based vaccine bypasses pre-existing immunity to the vaccine carrier and improves the immune response in mice Vesicular stomatitis virus-based ebola vaccine is well-tolerated and protects immunocompromised nonhuman primates Current ebola vaccines Mucosal immunization of cynomolgus macaques with the VSVDeltaG/ZEBOVGP vaccine stimulates strong ebola GP-specific immune responses A Recombinant Vesicular Stomatitis Virus Ebola Vaccine — Preliminary Report Ebolavirus vaccines for humans and apes Clinical development of Ebola vaccines Mouse models for filovirus infections Antigenic subversion: a novel mechanism of host immune evasion by Ebola virus Neutralizing ebolavirus: structural insights into the envelope glycoprotein and antibodies targeted against it Structure of the Ebola virus glycoprotein bound to an antibody from a human survivor Ad35 and ad26 vaccine vectors induce potent and cross-reactive antibody and T-cell responses to multiple filovirus species Ebola and Marburg virus vaccines.A Perspective on the Development of Plant-Made Vaccines in the Fight against Ebola Virus "Filoviruses": a real pandemic threat?Vesicular stomatitis virus-based vaccines protect nonhuman primates against Bundibugyo ebolavirus Enhanced protection against Ebola virus mediated by an improved adenovirus-based vaccine Demonstration of cross-protective vaccine immunity against an emerging pathogenic Ebolavirus Species Towards broad protection against Ebolaviruses.Vaccinating captive chimpanzees to save wild chimpanzees.Ebola Vaccine: How Far are we?A replicating cytomegalovirus-based vaccine encoding a single Ebola virus nucleoprotein CTL epitope confers protection against Ebola virus Protective efficacy of neutralizing monoclonal antibodies in a nonhuman primate model of Ebola hemorrhagic fever.Chimpanzee adenovirus vaccine generates acute and durable protective immunity against ebolavirus challenge.Human Ebola virus infection in West Africa: a review of available therapeutic agents that target different steps of the life cycle of Ebola virus.EBOLA VACCINE. VSV-EBOV rapidly protects macaques against infection with the 2014/15 Ebola virus outbreak strain.Use of ChAd3-EBO-Z Ebola virus vaccine in Malian and US adults, and boosting of Malian adults with MVA-BN-Filo: a phase 1, single-blind, randomised trial, a phase 1b, open-label and double-blind, dose-escalation trial, and a nested, randomised, doub Ebolavirus Glycoprotein Fc Fusion Protein Protects Guinea Pigs against Lethal Challenge.A DNA vaccine for Ebola virus is safe and immunogenic in a phase I clinical trial Recombinant vesicular stomatitis virus vector mediates postexposure protection against Sudan Ebola hemorrhagic fever in nonhuman primates Vesicular stomatitis virus-based vaccines protect nonhuman primates against aerosol challenge with Ebola and Marburg viruses.Single-injection vaccine protects nonhuman primates against infection with marburg virus and three species of ebola virus.Vesicular stomatitis virus-based Ebola vaccines with improved cross-protective efficacy.The emergence of ebola as a global health security threat: from 'lessons learned' to coordinated multilateral containment efforts.Ebola virus glycoprotein Fc fusion protein confers protection against lethal challenge in vaccinated mice.Safety and immunogenicity of DNA vaccines encoding Ebolavirus and Marburgvirus wild-type glycoproteins in a phase I clinical trial Recombinant adenovirus serotype 26 (Ad26) and Ad35 vaccine vectors bypass immunity to Ad5 and protect nonhuman primates against ebolavirus challenge Evasion of the interferon-mediated antiviral response by filoviruses.Single immunization with a monovalent vesicular stomatitis virus-based vaccine protects nonhuman primates against heterologous challenge with Bundibugyo ebolavirus.

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P2860

Immune protection of nonhuman primates against Ebola virus with single low-dose adenovirus vectors encoding modified GPs

http://www.wikidata.org/entity/Q28768041

description

2006 nî lūn-bûn

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2006 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2006 թվականի հունիսին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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JOURNAL.PMED.0030177

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Immune protection of nonhuman ...... vectors encoding modified GPs

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Devon J Shedlock

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Jerome H H V Custers

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Joan B Geisbert

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Laurie Lamoreaux

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Ling Xu

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Maria G Pau

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Mario Roederer

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Nancy J Sullivan

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Paul M Popernack

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Richard A Koup

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P2860

pH-dependent entry of severe acute respiratory syndrome coronavirus is mediated by the spike glycoprotein and enhanced by dendritic cell transfer through DC-SIGN

Development of a preventive vaccine for Ebola virus infection in primates

Improved adenovirus vectors for infection of cardiovascular tissues

Comprehensive analysis of ebola virus GP1 in viral entry.

Biochemical analysis of the secreted and virion glycoproteins of Ebola virus.

Protection from Ebola virus mediated by cytotoxic T lymphocytes specific for the viral nucleoprotein

Live attenuated recombinant vaccine protects nonhuman primates against Ebola and Marburg viruses.

Immunization for Ebola virus infection.

Accelerated vaccination for Ebola virus haemorrhagic fever in non-human primates.

Pathogenesis of Ebola hemorrhagic fever in cynomolgus macaques: evidence that dendritic cells are early and sustained targets of infection

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e177

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10.1371/JOURNAL.PMED.0030177

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6

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Peter B. Jahrling

Thomas W Geisbert

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2006-06-01T00:00:00Z

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7097150

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16683867

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vector-borne disease

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1459482

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