Widespread macromolecular interaction perturbations in human genetic disorders
about
Multi-OMICs and Genome Editing Perspectives on Liver Cancer Signaling NetworksUsing biological networks to integrate, visualize and analyze genomics dataAutoimmune diseases - connecting risk alleles with molecular traits of the immune system.Forward Individualized Medicine from Personal Genomes to InteractomesFundamentals of protein interaction network mappingHuman protein interaction networks across tissues and diseasesPrefoldin Promotes Proteasomal Degradation of Cytosolic Proteins with Missense Mutations by Maintaining Substrate Solubility.Bridging the gap between clinicians and systems biologists: from network biology to translational biomedical researchApplications of comparative evolution to human disease geneticsPooled-matrix protein interaction screens using Barcode Fusion GeneticsMitochondrial Protein Interaction Mapping Identifies Regulators of Respiratory Chain FunctionA Pan-Cancer Catalogue of Cancer Driver Protein Interaction InterfacesGenetic variants in Alzheimer disease - molecular and brain network approachesComprehensive assessment of cancer missense mutation clustering in protein structuresThe BioGRID interaction database: 2017 updateAn organelle-specific protein landscape identifies novel diseases and molecular mechanismsProtein Destabilization as a Common Factor in Diverse Inherited Disorders.StructMAn: annotation of single-nucleotide polymorphisms in the structural contextInsights into cancer severity from biomolecular interaction mechanisms.Identifying network-based biomarkers of complex diseases from high-throughput data.Practical aspects of gene regulatory inference via conditional inference forests from expression data.A Proteome-wide Fission Yeast Interactome Reveals Network Evolution Principles from Yeasts to Human.Variation Interpretation Predictors: Principles, Types, Performance, and Choice.Protein-protein interactions as drug targets.Structure-Based Analysis Reveals Cancer Missense Mutations Target Protein Interaction InterfacesKinMutRF: a random forest classifier of sequence variants in the human protein kinase superfamily.The Loss and Gain of Functional Amino Acid Residues Is a Common Mechanism Causing Human Inherited DiseaseAlpha Helices Are More Robust to Mutations than Beta StrandsMEDICI: Mining Essentiality Data to Identify Critical Interactions for Cancer Drug Target Discovery and Development.Hallmarks of therapeutic management of the cystic fibrosis functional landscape.Rewiring of the inferred protein interactome during blood development studied with the tool PPICompare.Next-Generation Sequencing for Binary Protein-Protein Interactions.Survey of variation in human transcription factors reveals prevalent DNA binding changes.An Atlas of the Human Kinome Reveals the Mutational Landscape Underlying Dysregulated Phosphorylation Cascades in Cancer.Advances in computational approaches for prioritizing driver mutations and significantly mutated genes in cancer genomesIncreasing Role of Titin Mutations in Neuromuscular Disorders.iRegNet3D: three-dimensional integrated regulatory network for the genomic analysis of coding and non-coding disease mutations.Interactome disassembly during apoptosis occurs independent of caspase cleavage.Identification of Topological Network Modules in Perturbed Protein Interaction Networks.The cancer cell map initiative: defining the hallmark networks of cancer.
P2860
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P2860
Widespread macromolecular interaction perturbations in human genetic disorders
description
2015 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2015
@ast
scientific journal article
@en
wetenschappelijk artikel (gepubliceerd op 2015/04/23)
@nl
wissenschaftlicher Artikel
@de
наукова стаття, опублікована у квітні 2015
@uk
مقالة علمية (نشرت في 23-4-2015)
@ar
name
Widespread macromolecular interaction perturbations in human genetic disorders
@ast
Widespread macromolecular interaction perturbations in human genetic disorders
@en
type
label
Widespread macromolecular interaction perturbations in human genetic disorders
@ast
Widespread macromolecular interaction perturbations in human genetic disorders
@en
prefLabel
Widespread macromolecular interaction perturbations in human genetic disorders
@ast
Widespread macromolecular interaction perturbations in human genetic disorders
@en
P2093
P2860
P50
P921
P3181
P1433
P1476
Widespread macromolecular interaction perturbations in human genetic disorders
@en
P2093
Akash A Shah
Alex Leighton
Alexandre Palagi
Amelie Dricot
Amitabh Sharma
Ani K Stoyanova
Atanas Kamburov
Benoit Charloteaux
Bonnie Berger
Changyu Fan
P2860
P304
P3181
P356
10.1016/J.CELL.2015.04.013
P407
P50
P577
2015-04-23T00:00:00Z