Recruitment of the human Cdt1 replication licensing protein by the loop domain of Hec1 is required for stable kinetochore-microtubule attachment
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MAPping the Ndc80 loop in cancer: A possible link between Ndc80/Hec1 overproduction and cancer formationThe current view for the silencing of the spindle assembly checkpointThe Geminin and Idas Coiled Coils Preferentially Form a Heterodimer That Inhibits Geminin Function in DNA Replication LicensingRegulation and Function of Cdt1; A Key Factor in Cell Proliferation and Genome StabilityLateral to end-on conversion of chromosome-microtubule attachment requires kinesins CENP-E and MCAKConnecting the microtubule attachment status of each kinetochore to cell cycle arrest through the spindle assembly checkpoint.Looping in on Ndc80 - how does a protein loop at the kinetochore control chromosome segregation?Alp7/TACC recruits kinesin-8-PP1 to the Ndc80 kinetochore protein for timely mitotic progression and chromosome movement.SCF-FBXO31 E3 ligase targets DNA replication factor Cdt1 for proteolysis in the G2 phase of cell cycle to prevent re-replication.The kinetochore encodes a mechanical switch to disrupt spindle assembly checkpoint signalling.CDK1-dependent inhibition of the E3 ubiquitin ligase CRL4CDT2 ensures robust transition from S Phase to Mitosis.The KMN protein network--chief conductors of the kinetochore orchestraThe internal loop of fission yeast Ndc80 binds Alp7/TACC-Alp14/TOG and ensures proper chromosome attachment.Principles and concepts of DNA replication in bacteria, archaea, and eukarya.Geminin deploys multiple mechanisms to regulate Cdt1 before cell division thus ensuring the proper execution of DNA replication.The composition, functions, and regulation of the budding yeast kinetochoreDynamic regulation of kinetochore-microtubule interaction during mitosis.Microtubule attachment and spindle assembly checkpoint signalling at the kinetochore.Flipping the switch from g1 to s phase with e3 ubiquitin ligasesLinked in: formation and regulation of microtubule attachments during chromosome segregation.The contribution of dormant origins to genome stability: from cell biology to human genetics.Genome-scale prediction of moonlighting proteins using diverse protein association information.Targeting mitotic pathways for endocrine-related cancer therapeutics.Aurora-B kinase pathway controls the lateral to end-on conversion of kinetochore-microtubule attachments in human cells.Coiled-coils: The long and short of it.Ndc80 Loop as a protein-protein interaction motif.Imaging mouse cancer models in vivo using reporter transgenes.Ubiquitin-conjugating enzyme E2T (UBE2T) and denticleless protein homolog (DTL) are linked to poor outcome in breast and lung cancers.Combining Mitotic Cell Synchronization and High Resolution Confocal Microscopy to Study the Role of Multifunctional Cell Cycle Proteins During Mitosis.Rapid DNA replication origin licensing protects stem cell pluripotency.Multitasking Ska in Chromosome Segregation: Its Distinct Pools Might Specify Various Functions.Super-Resolution Microscopy in Studying the Structure and Function of the Cell Nucleus.The Temporal Regulation of S Phase Proteins During G1.
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P2860
Recruitment of the human Cdt1 replication licensing protein by the loop domain of Hec1 is required for stable kinetochore-microtubule attachment
description
2012 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի մայիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2012
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scientific journal article
@en
wetenschappelijk artikel (gepubliceerd op 2012/05/13)
@nl
wissenschaftlicher Artikel
@de
наукова стаття, опублікована в травні 2012
@uk
مقالة علمية (نشرت في 13-5-2012)
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name
Recruitment of the human Cdt1 ...... tochore-microtubule attachment
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Recruitment of the human Cdt1 ...... tochore-microtubule attachment
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type
label
Recruitment of the human Cdt1 ...... tochore-microtubule attachment
@ast
Recruitment of the human Cdt1 ...... tochore-microtubule attachment
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prefLabel
Recruitment of the human Cdt1 ...... tochore-microtubule attachment
@ast
Recruitment of the human Cdt1 ...... tochore-microtubule attachment
@en
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P3181
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Recruitment of the human Cdt1 ...... tochore-microtubule attachment
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Dawn A D Chasse
Dileep Varma
E D Salmon
Jennifer G DeLuca
Karen T Reidy
Kathleen R Nevis
Lynsie J R Sundin
Srikripa Chandrasekaran
Xiaohu Wan
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P2888
P304
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P356
10.1038/NCB2489
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2012-05-13T00:00:00Z
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P6179
1031217824