Genomic characterization of recent human LINE-1 insertions: evidence supporting random insertion
about
Hot L1s account for the bulk of retrotransposition in the human populationMany LINE1 elements contribute to the transcriptome of human somatic cellsMolecular archeology of L1 insertions in the human genome.Identifying related L1 retrotransposons by analyzing 3' transduced sequencesGenomic rearrangements by LINE-1 insertion-mediated deletion in the human and chimpanzee lineagesThe Influence of LINE-1 and SINE Retrotransposons on Mammalian GenomesExpressing genes do not forget their LINEs: transposable elements and gene expressionLINE-1 elements in structural variation and diseaseLINE-1 retrotransposition activity in human genomesPeriodic explosive expansion of human retroelements associated with the evolution of the hominoid primateHigh-throughput sequencing reveals extensive variation in human-specific L1 content in individual human genomesEnd-sequencing and characterization of silkworm (Bombyx mori) bacterial artificial chromosome librariesActive human retrotransposons: variation and diseaseNatural mutagenesis of human genomes by endogenous retrotransposonsAlu and b1 repeats have been selectively retained in the upstream and intronic regions of genes of specific functional classes.Mobile element scanning (ME-Scan) by targeted high-throughput sequencing.Genome-Wide Estimates of Transposable Element Insertion and Deletion Rates in Drosophila Melanogaster.ATLAS: a system to selectively identify human-specific L1 insertions.Allelic heterogeneity in LINE-1 retrotransposition activity.Tracing the LINEs of human evolutionA mobile threat to genome stability: The impact of non-LTR retrotransposons upon the human genome.Mobilizing diversity: transposable element insertions in genetic variation and disease.L1 integration in a transgenic mouse modelRescuing Alu: recovery of new inserts shows LINE-1 preserves Alu activity through A-tail expansionNatural genetic variation caused by transposable elements in humansMobile element scanning (ME-Scan) identifies thousands of novel Alu insertions in diverse human populations.Active retrotransposition by a synthetic L1 element in miceThe insertional history of an active family of L1 retrotransposons in humansCharacterization of pre-insertion loci of de novo L1 insertions.Repetitive sequence environment distinguishes housekeeping genes.Active Alu element "A-tails": size does matterEndonuclease-independent insertion provides an alternative pathway for L1 retrotransposition in the human genomeLINE-1-derived poly(A) microsatellites undergo rapid shortening and create somatic and germline mosaicism in miceControlled insertional mutagenesis using a LINE-1 (ORFeus) gene-trap mouse model.An alternative pathway for Alu retrotransposition suggests a role in DNA double-strand break repairA comprehensive analysis of recently integrated human Ta L1 elementsEvidence consistent with human L1 retrotransposition in maternal meiosis I.Linear decay of retrotransposon antisense bias across genes is contingent upon tissue specificity.Transduction-specific ATLAS reveals a cohort of highly active L1 retrotransposons in human populations.Internal priming: an opportunistic pathway for L1 and Alu retrotransposition in hominins.
P2860
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P2860
Genomic characterization of recent human LINE-1 insertions: evidence supporting random insertion
description
2001 nî lūn-bûn
@nan
2001 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Genomic characterization of re ...... ce supporting random insertion
@ast
Genomic characterization of re ...... ce supporting random insertion
@en
type
label
Genomic characterization of re ...... ce supporting random insertion
@ast
Genomic characterization of re ...... ce supporting random insertion
@en
prefLabel
Genomic characterization of re ...... ce supporting random insertion
@ast
Genomic characterization of re ...... ce supporting random insertion
@en
P2860
P356
P1433
P1476
Genomic characterization of re ...... ce supporting random insertion
@en
P2093
G D Swergold
I Ovchinnikov
P2860
P304
P356
10.1101/GR.194701
P407
P577
2001-12-01T00:00:00Z