Target interaction profiling of midostaurin and its metabolites in neoplastic mast cells predicts distinct effects on activation and growth
about
Advances in the Classification and Treatment of Mastocytosis: Current Status and Outlook toward the Future.Midostaurin for the treatment of acute myeloid leukemia.BTK inhibition is a potent approach to block IgE-mediated histamine release in human basophils.Mastocytosis: 2016 updated WHO classification and novel emerging treatment concepts.A spatiotemporal hypothesis for the regulation, role, and targeting of AMPK in prostate cancer.Midostaurin: First Global Approval.Characterization of midostaurin as a dual inhibitor of FLT3 and SYK and potentiation of FLT3 inhibition against FLT3-ITD-driven leukemia harboring activated SYK kinase.Emerging therapies for acute myeloid leukemia: translating biology into the clinic.Use of the relative release index for histamine in LAD2 cells to evaluate the potential anaphylactoid effects of drugs.Midostaurin: a magic bullet that blocks mast cell expansion and activation.Drug-induced inhibition of phosphorylation of STAT5 overrides drug resistance in neoplastic mast cells.Infliction of proteotoxic stresses by impairment of the unfolded protein response or proteasomal inhibition as a therapeutic strategy for mast cell leukemia.The KIT and PDGFRA switch-control inhibitor DCC-2618 blocks growth and survival of multiple neoplastic cell types in advanced mastocytosis.KIT D816V Positive Acute Mast Cell Leukemia Associated with Normal Karyotype Acute Myeloid Leukemia.Ludwig Boltzmann Cluster Oncology (LBC ONC): first 10 years and future perspectivesClonal eosinophil and mast cell diseases: different in the same way?
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P2860
Target interaction profiling of midostaurin and its metabolites in neoplastic mast cells predicts distinct effects on activation and growth
description
2016 nî lūn-bûn
@nan
2016 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2016 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
name
Target interaction profiling o ...... fects on activation and growth
@ast
Target interaction profiling o ...... fects on activation and growth
@en
type
label
Target interaction profiling o ...... fects on activation and growth
@ast
Target interaction profiling o ...... fects on activation and growth
@en
prefLabel
Target interaction profiling o ...... fects on activation and growth
@ast
Target interaction profiling o ...... fects on activation and growth
@en
P2093
P2860
P50
P356
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Target interaction profiling o ...... fects on activation and growth
@en
P2093
G E Winter
G Superti-Furga
K L Bennett
M Gridling
P2860
P2888
P304
P356
10.1038/LEU.2015.242
P407
P577
2016-02-01T00:00:00Z
P6179
1017123538