Synthetic oligonucleotides recruit ILF2/3 to RNA transcripts to modulate splicing - Wikidata - awgldk - TriplyDB

Synthetic oligonucleotides recruit ILF2/3 to RNA transcripts to modulate splicing

Synthetic oligonucleotides recruit ILF2/3 to RNA transcripts to modulate splicing

http://www.wikidata.org/entity/Q28830393

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RNA toxicity from the ALS/FTD C9ORF72 expansion is mitigated by antisense intervention A chemical view of oligonucleotides for exon skipping and related drug applications Synthesis and Antisense Properties of Fluoro Cyclohexenyl Nucleic Acid (F-CeNA), a Nuclease Stable Mimic of 2′-Fluoro RNA Evaluation of 2'-Deoxy-2'-fluoro Antisense Oligonucleotides for Exon Skipping in Duchenne Muscular Dystrophy 2'-Fluoro RNA shows increased Watson-Crick H-bonding strength and stacking relative to RNA: evidence from NMR and thermodynamic data.Pharmacology of a central nervous system delivered 2'-O-methoxyethyl-modified survival of motor neuron splicing oligonucleotide in mice and nonhuman primates.Oligonucleotide-based strategies to combat polyglutamine diseases.Structure/affinity studies in the bicyclo-DNA series: Synthesis and properties of oligonucleotides containing bc(en)-T and iso-tricyclo-T nucleosides.Targeting SR proteins improves SMN expression in spinal muscular atrophy cells.Defining the factors that contribute to on-target specificity of antisense oligonucleotides.Antisense oligonucleotides capable of promoting specific target mRNA reduction via competing RNase H1-dependent and independent mechanisms.Nuclear factor 90 uses an ADAR2-like binding mode to recognize specific bases in dsRNA.Antisense-based therapy for the treatment of spinal muscular atrophy Targeting RNA splicing for disease therapy.Evolution of thermophilic DNA polymerases for the recognition and amplification of C2'-modified DNA.Hepatotoxic potential of therapeutic oligonucleotides can be predicted from their sequence and modification pattern.ss-siRNAs allele selectively inhibit ataxin-3 expression: multiple mechanisms for an alternative gene silencing strategy.Antisense Oligonucleotides: Treatment Strategies and Cellular Internalization.2'-Fluoro-modified phosphorothioate oligonucleotide can cause rapid degradation of P54nrb and PSF.Exon skipping: a first in class strategy for Duchenne muscular dystrophy.Non-coding RNAs as drug targets.Biological applications of xeno nucleic acids.Specific Increase of Protein Levels by Enhancing Translation Using Antisense Oligonucleotides Targeting Upstream Open Frames.A novel long intergenic noncoding RNA indispensable for the cleavage of mouse two-cell embryos.Synthesis, duplex stabilization and structural properties of a fluorinated carbocyclic LNA analogue Synthesis and duplex-stabilizing properties of fluorinated N-methanocarbathymidine analogues locked in the C3'-endo conformation.Exploiting differential RNA splicing patterns: a potential new group of therapeutic targets in cancer.miRNA Targeting Drugs: The Next Blockbusters?2'β-Fluoro-Tricyclo Nucleic Acids (2'F-tc-ANA): Thermal Duplex Stability, Structural Studies, and RNase H Activation.Antisense therapeutics: New ways to nudge splicing.Identifying pathway modules of tuberculosis in children by analyzing multiple different networks.Alternative-splicing defects in cancer: Splicing regulators and their downstream targets, guiding the way to novel cancer therapeutics.Conjugation of PEG and gold nanoparticles to increase the accessibility and valency of tethered RNA splicing enhancers

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P2860

Synthetic oligonucleotides recruit ILF2/3 to RNA transcripts to modulate splicing

http://www.wikidata.org/entity/Q28830393

description

2012 nî lūn-bûn

@nan

2012 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2012 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2012年の論文

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2012年学术文章

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2012年学术文章

@zh-cn

2012年学术文章

@zh-hans

2012年学术文章

@zh-my

2012年学术文章

@zh-sg

2012年學術文章

@yue

name

Synthetic oligonucleotides recruit ILF2/3 to RNA transcripts to modulate splicing

@ast

Synthetic oligonucleotides recruit ILF2/3 to RNA transcripts to modulate splicing

@en

type

label

Synthetic oligonucleotides recruit ILF2/3 to RNA transcripts to modulate splicing

@ast

Synthetic oligonucleotides recruit ILF2/3 to RNA transcripts to modulate splicing

@en

prefLabel

Synthetic oligonucleotides recruit ILF2/3 to RNA transcripts to modulate splicing

@ast

Synthetic oligonucleotides recruit ILF2/3 to RNA transcripts to modulate splicing

@en

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Nature Chemical Biology

P1476

Synthetic oligonucleotides recruit ILF2/3 to RNA transcripts to modulate splicing

@en

P2093

C Frank Bennett

http://www.w3.org/2001/XMLSchema#string

Frank Rigo

http://www.w3.org/2001/XMLSchema#string

Seung J Chun

http://www.w3.org/2001/XMLSchema#string

Thazha P Prakash

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Yimin Hua

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P2860

Cloning and sequencing of the cDNA encoding an isoform of microtubule-associated protein tau containing four tandem repeats: differential expression of tau protein mRNAs in human brain

bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death

Crystal structure and improved antisense properties of 2'-O-(2-methoxyethyl)-RNA

The spliceosome: design principles of a dynamic RNP machine

RNA-binding proteins: modular design for efficient function

The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

Mechanisms of alternative splicing regulation: insights from molecular and genomics approaches

RNA processing and its regulation: global insights into biological networks

RNA and disease

A single nucleotide in the SMN gene regulates splicing and is responsible for spinal muscular atrophy

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10.1038/NCHEMBIO.939

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6

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8

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Adrian Robert Krainer

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2012-04-15T00:00:00Z

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1024361647

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22504300

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5021312

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