Functionally defined therapeutic targets in diffuse intrinsic pontine glioma - Wikidata - awgldk - TriplyDB

Functionally defined therapeutic targets in diffuse intrinsic pontine glioma

Functionally defined therapeutic targets in diffuse intrinsic pontine glioma

http://www.wikidata.org/entity/Q28833173

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JHH-DIPG-1 NEM157 NEM163 NEM165 NEM168 SF7761 SU-DIPG-IV SU-DIPG-VI SU-DIPG-XIII SU-pcGBM-2 VUMC-DIPG-A VUMC-DIPG-B

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Hepatoblastoma: A Need for Cell Lines and Tissue Banks to Develop Targeted Drug Therapies Open access chemical probes for epigenetic targets Pre-Clinical Models of Diffuse Intrinsic Pontine Glioma Future Clinical Trials in DIPG: Bringing Epigenetics to the Clinic Spatial genomic heterogeneity in diffuse intrinsic pontine and midline high-grade glioma: implications for diagnostic biopsy and targeted therapeutics Pre-Clinical Study of Panobinostat in Xenograft and Genetically Engineered Murine Diffuse Intrinsic Pontine Glioma Models Diffuse Intrinsic Pontine Glioma: New Pathophysiological Insights and Emerging Therapeutic Targets Long-term survival of an infant with diffuse brainstem lesion diagnosed by prenatal MRI: a case report and review of the literature.Detection of Histone H3 mutations in cerebrospinal fluid-derived tumor DNA from children with diffuse midline glioma.A Protocol for Rapid Post-mortem Cell Culture of Diffuse Intrinsic Pontine Glioma (DIPG).Epigenetic Regulation of Telomere Maintenance for Therapeutic Interventions in Gliomas.Pediatric high-grade glioma: biologically and clinically in need of new thinking Small molecules targeting histone demethylase genes (KDMs) inhibit growth of temozolomide-resistant glioblastoma cells Targeting Epigenetic Pathways in the Treatment of Pediatric Diffuse (High Grade) Gliomas.Successful strategies in the discovery of small-molecule epigenetic modulators with anticancer potential.Disrupting NOTCH Slows Diffuse Intrinsic Pontine Glioma Growth, Enhances Radiation Sensitivity, and Shows Combinatorial Efficacy With Bromodomain Inhibition Development of a DIPG Orthotopic Model in Mice Using an Implantable Guide-Screw System.Combination therapy design for maximizing sensitivity and minimizing toxicity.Repurposing the anti-epileptic drug sodium valproate as an adjuvant treatment for diffuse intrinsic pontine glioma.Common mutations in ALK2/ACVR1, a multi-faceted receptor, have roles in distinct pediatric musculoskeletal and neural orphan disorders.Mutations in chromatin machinery and pediatric high-grade glioma Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma Dual Inhibition of PI3K/AKT and MEK/ERK Pathways Induces Synergistic Antitumor Effects in Diffuse Intrinsic Pontine Glioma Cells.Convection enhanced delivery of panobinostat (LBH589)-loaded pluronic nano-micelles prolongs survival in the F98 rat glioma model.Development of the SIOPE DIPG network, registry and imaging repository: a collaborative effort to optimize research into a rare and lethal disease The international diffuse intrinsic pontine glioma registry: an infrastructure to accelerate collaborative research for an orphan disease.Glioblastoma targeted therapy: updated approaches from recent biological insights.An epigenetic gateway to brain tumor cell identity.Epigenetic blockade of neoplastic transformation by bromodomain and extra-terminal (BET) domain protein inhibitor JQ-1.Advances in the molecular genetics of gliomas - implications for classification and therapy.AshwaMAX and Withaferin A inhibits gliomas in cellular and murine orthotopic models Diffuse Intrinsic Pontine Glioma: Time for Cautious Optimism.Oncogenic Mechanisms of Histone H3 Mutations.Epigenetic modification in chromatin machinery and its deregulation in pediatric brain tumors: Insight into epigenetic therapies.The role of histone modifications and telomere alterations in the pathogenesis of diffuse gliomas in adults and children.Epigenetic Targeted Therapy for Diffuse Intrinsic Pontine Glioma New Molecular Considerations for Glioma: IDH, ATRX, BRAF, TERT, H3 K27M.Therapeutic Targeting of Histone Modifications in Adult and Pediatric High-Grade Glioma.Molecular Diagnostics of Gliomas Using Next Generation Sequencing of a Glioma-Tailored Gene Panel.Potential New Therapies for Pediatric Diffuse Intrinsic Pontine Glioma.

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Functionally defined therapeutic targets in diffuse intrinsic pontine glioma

http://www.wikidata.org/entity/Q28833173

description

2015 nî lūn-bûn

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2015 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2015 թվականի հունիսին հրատարակված գիտական հոդված

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年论文

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name

Functionally defined therapeutic targets in diffuse intrinsic pontine glioma

@ast

Functionally defined therapeutic targets in diffuse intrinsic pontine glioma

@en

type

label

Functionally defined therapeutic targets in diffuse intrinsic pontine glioma

@ast

Functionally defined therapeutic targets in diffuse intrinsic pontine glioma

@en

prefLabel

Functionally defined therapeutic targets in diffuse intrinsic pontine glioma

@ast

Functionally defined therapeutic targets in diffuse intrinsic pontine glioma

@en

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Nature Medicine

P1476

Functionally defined therapeutic targets in diffuse intrinsic pontine glioma

@en

P2093

Anitha Ponnuswami

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Catherine S Grasso

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Charles Keller

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Dannis G van Vuurden

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Elaine C Huang

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Eric H Raabe

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Esther Hulleman

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Hua Mao

http://www.w3.org/2001/XMLSchema#string

Jinu Abraham

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Katherine E Warren

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P2860

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

Mapping and quantifying mammalian transcriptomes by RNA-Seq

Reduced H3K27me3 and DNA hypomethylation are major drivers of gene expression in K27M mutant pediatric high-grade gliomas

K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas

Targeted capture and massively parallel sequencing of 12 human exomes

Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas

Recurrent activating ACVR1 mutations in diffuse intrinsic pontine glioma

In vitro drug response and efflux transporters associated with drug resistance in pediatric high grade glioma and diffuse intrinsic pontine glioma

The mutational landscape of lethal castration-resistant prostate cancer

Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma

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555-9

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5122388

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10.1038/NM.3855

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P433

6

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21

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Cynthia Hawkins

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2015-06-01T00:00:00Z

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1001212323

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25939062

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diffuse intrinsic pontine glioma

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4862411

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