Hsp90 protein interacts with phosphorothioate oligonucleotides containing hydrophobic 2'-modifications and enhances antisense activity
about
Specific Increase of Protein Levels by Enhancing Translation Using Antisense Oligonucleotides Targeting Upstream Open Frames.Strategies for In Vivo Screening and Mitigation of Hepatotoxicity Associated with Antisense Drugs.Intra-endosomal trafficking mediated by lysobisphosphatidic acid contributes to intracellular release of phosphorothioate-modified antisense oligonucleotidesMolecular Mechanisms of Antisense Oligonucleotides.Nucleic acid binding proteins affect the subcellular distribution of phosphorothioate antisense oligonucleotides.RNA Therapeutics in Oncology: Advances, Challenges, and Future Directions.BNANC Gapmers Revert Splicing and Reduce RNA Foci with Low Toxicity in Myotonic Dystrophy Cells.Oligonucleotide therapies for disorders of the nervous system.Acute hepatotoxicity of 2' fluoro-modified 5-10-5 gapmer phosphorothioate oligonucleotides in mice correlates with intracellular protein binding and the loss of DBHS proteins.Cellular uptake mediated by epidermal growth factor receptor facilitates the intracellular activity of phosphorothioate-modified antisense oligonucleotides.COPII vesicles can affect the activity of antisense oligonucleotides by facilitating the release of oligonucleotides from endocytic pathways
P2860
Q39390082-D069EA12-FA13-4813-8D9B-C83C7CEF5D5BQ41191017-3878598C-10EB-492A-89E2-6D4A1C150011Q41693957-5E5FCA70-C1D1-4324-98BC-AD1614A74E6DQ42293314-DCC58E7F-D6DB-4A53-B2FE-C61F4CC6FBA1Q47134784-6CF41895-1976-4DF8-8AE7-FDA09C3EDEA2Q47786398-C2CE34DC-1408-402B-8B49-7FC7C0215E1CQ47884385-9B60315A-1781-4315-93AB-3CFCA3F45BA5Q48288187-AF7FB12E-F1DD-41B8-A8C3-EE7E2822750EQ49489377-274FC6C3-8C19-444E-A5F8-9A72EAA4A4EEQ51743392-EC964E84-536E-4FDF-8336-F5D7FF31BF79Q58708488-925E5B9D-94B4-4DF3-898F-3A9E5E6392D3
P2860
Hsp90 protein interacts with phosphorothioate oligonucleotides containing hydrophobic 2'-modifications and enhances antisense activity
description
2016 nî lūn-bûn
@nan
2016 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2016 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
name
Hsp90 protein interacts with p ...... nd enhances antisense activity
@ast
Hsp90 protein interacts with p ...... nd enhances antisense activity
@en
type
label
Hsp90 protein interacts with p ...... nd enhances antisense activity
@ast
Hsp90 protein interacts with p ...... nd enhances antisense activity
@en
prefLabel
Hsp90 protein interacts with p ...... nd enhances antisense activity
@ast
Hsp90 protein interacts with p ...... nd enhances antisense activity
@en
P2093
P2860
P356
P1476
Hsp90 protein interacts with p ...... nd enhances antisense activity
@en
P2093
Garth A Kinberger
Joshua G Nichols
Stanley T Crooke
Thazha P Prakash
Xue-Hai Liang
P2860
P304
P356
10.1093/NAR/GKW144
P407
P577
2016-05-05T00:00:00Z