A novel phosphorylation site, Serine 199, in the C-terminus of cardiac troponin I regulates calcium sensitivity and susceptibility to calpain-induced proteolysis
about
TNNI1, TNNI2 and TNNI3: Evolution, regulation, and protein structure-function relationships.Functional phosphorylation sites in cardiac myofilament proteins are evolutionarily conserved in skeletal myofilament proteinsThe functional significance of the last 5 residues of the C-terminus of cardiac troponin I.Cardiac troponin structure-function and the influence of hypertrophic cardiomyopathy associated mutations on modulation of contractility.Heart Failure-Related Hyperphosphorylation in the Cardiac Troponin I C Terminus Has Divergent Effects on Cardiac Function In Vivo.The continuing evolution of cardiac troponin I biomarker analysis: from protein to proteoform.Changes in contractile protein expression are linked to ventricular stiffness in infants with pulmonary hypertension or right ventricular hypertrophy due to congenital heart disease.Monophosphorylation of cardiac troponin-I at Ser23/24 is sufficient to regulate cardiac myofibrillar Ca2+ sensitivity and calpain-induced proteolysis.
P2860
36899b7522c1c04e5d21721dcf490fa7b91974733a726bf22e849aa0ca345c55c349a9f955e91ed96658b8198ea27b67456ae3ac10e5a0234c7349587d85859fa1f6f93bb5e5e30db3459c1f153e716f97e8de7722df5b4c259e14516ee6c0bd21b1e2f09a61410b736e22e6d540b5c288b0755f8518672be7e59115e4a273bd08ca3f524415b8cdeb3e3d53f9a2caa86f8d817e4f7041278cc64f9e23b15a1d
P248
Q30380968-A80DAAB8-B7C6-4FBA-A1A9-CB2A45BC1D4AQ36965797-4E3851E5-D669-4D1D-A612-159BC9CBB72CQ36984498-15EE8663-9955-4E0D-8F0B-8ACA6398D96AQ38724869-F7CF7856-28DD-4418-817F-EA167575A050Q47682931-CA099F34-8ABF-47BA-9D6D-469AF3447A37Q47687870-26724097-4E21-4E08-95D0-AB8345900A16Q48222584-7D1E9C4B-48D5-42F2-B223-67C3C391E1E7Q54115414-3CEF7556-B152-404F-9C8F-7316AF2BAFD4
P2860
A novel phosphorylation site, Serine 199, in the C-terminus of cardiac troponin I regulates calcium sensitivity and susceptibility to calpain-induced proteolysis
description
2015 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի մայիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2015
@ast
im Mai 2015 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
wetenschappelijk artikel (gepubliceerd op 2015/05/01)
@nl
наукова стаття, опублікована в травні 2015
@uk
مقالة علمية (نشرت في مايو 2015)
@ar
name
A novel phosphorylation site, ...... to calpain-induced proteolysis
@ast
A novel phosphorylation site, ...... to calpain-induced proteolysis
@en
type
label
A novel phosphorylation site, ...... to calpain-induced proteolysis
@ast
A novel phosphorylation site, ...... to calpain-induced proteolysis
@en
prefLabel
A novel phosphorylation site, ...... to calpain-induced proteolysis
@ast
A novel phosphorylation site, ...... to calpain-induced proteolysis
@en
P2093
P2860
P50
P921
P1476
A novel phosphorylation site, ...... to calpain-induced proteolysis
@en
P2093
Anne M Murphy
Cris dos Remedios
Jennifer E Van Eyk
Paul J M Wijnker
Pingbo Zhang
P2860
P304
P356
10.1016/J.YJMCC.2015.03.006
P577
2015-05-01T00:00:00Z