Transfection of small RNAs globally perturbs gene regulation by endogenous microRNAs
about
Predicting effective microRNA target sites in mammalian mRNAsThe mir-51 family of microRNAs functions in diverse regulatory pathways in Caenorhabditis elegansInhibition of microRNA function by antimiR oligonucleotidesIdentification of keratinocyte growth factor as a target of microRNA-155 in lung fibroblasts: implication in epithelial-mesenchymal interactionsWidespread regulatory activity of vertebrate microRNA* speciesExperimental strategies for microRNA target identificationCompeting endogenous RNA in cancer: a new pattern of gene expression regulationThe New State of the Art: Cas9 for Gene Activation and RepressionNeuronal dark matter: the emerging role of microRNAs in neurodegenerationThe "Observer Effect" in genome-wide surveys of protein-RNA interactionsA loss of FUS/TLS function leads to impaired cellular proliferationAbasic pivot substitution harnesses target specificity of RNA interferenceExperimental procedures to identify and validate specific mRNA targets of miRNAsMapping Argonaute and conventional RNA-binding protein interactions with RNA at single-nucleotide resolution using HITS-CLIP and CIMS analysisIdentification of a core miRNA-pathway regulatory network in glioma by therapeutically targeting miR-181d, miR-21, miR-23b, β-Catenin, CBP, and STAT3Quantitative proteomic analysis of gene regulation by miR-34a and miR-34cInduction of specific microRNAs inhibits cutaneous wound healingOff-target effects dominate a large-scale RNAi screen for modulators of the TGF-β pathway and reveal microRNA regulation of TGFBR2mRNA turnover rate limits siRNA and microRNA efficacySignatures of RNA binding proteins globally coupled to effective microRNA target sitesTarget mRNA abundance dilutes microRNA and siRNA activitySilencing disease genes in the laboratory and the clinicArgonaute proteins are key determinants of RNAi efficacy, toxicity, and persistence in the adult mouse liverInferring condition-specific miRNA activity from matched miRNA and mRNA expression data.Re-analysis of genome wide data on mammalian microRNA-mediated suppression of gene expressionThe expression of microRNA and microRNA clusters in the aging heartRelative contribution of sequence and structure features to the mRNA binding of Argonaute/EIF2C-miRNA complexes and the degradation of miRNA targets.Conserved expression patterns predict microRNA targetsSequence-non-specific effects of RNA interference triggers and microRNA regulators.Anti-Argonaute RIP-Chip shows that miRNA transfections alter global patterns of mRNA recruitment to microribonucleoprotein complexes.Inferring probabilistic miRNA-mRNA interaction signatures in cancers: a role-switch approach.The lncRNA VELUCT strongly regulates viability of lung cancer cells despite its extremely low abundance.Global and local competition between exogenously introduced microRNAs and endogenously expressed microRNAs.Oligonucleotide-based strategies to combat polyglutamine diseases.Modeling RNA interference in mammalian cellsMacros in microRNA target identification: a comparative analysis of in silico, in vitro, and in vivo approaches to microRNA target identification.Resolving Subcellular miRNA Trafficking and Turnover at Single-Molecule Resolution.Quantitative prediction of miRNA-mRNA interaction based on equilibrium concentrations.Mammalian Innate Immune Response to a Leishmania-Resident RNA Virus Increases Macrophage Survival to Promote Parasite PersistenceDual-targeting siRNAs
P2860
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P2860
Transfection of small RNAs globally perturbs gene regulation by endogenous microRNAs
description
2009 nî lūn-bûn
@nan
2009 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Transfection of small RNAs globally perturbs gene regulation by endogenous microRNAs
@ast
Transfection of small RNAs globally perturbs gene regulation by endogenous microRNAs
@en
type
label
Transfection of small RNAs globally perturbs gene regulation by endogenous microRNAs
@ast
Transfection of small RNAs globally perturbs gene regulation by endogenous microRNAs
@en
prefLabel
Transfection of small RNAs globally perturbs gene regulation by endogenous microRNAs
@ast
Transfection of small RNAs globally perturbs gene regulation by endogenous microRNAs
@en
P2860
P50
P921
P3181
P356
P1433
P1476
Transfection of small RNAs globally perturbs gene regulation by endogenous microRNAs
@en
P2093
Christina S Leslie
P2860
P2888
P304
P3181
P356
10.1038/NBT.1543
P407
P577
2009-06-01T00:00:00Z