The mechanism of intestinal uptake and transcellular transport of IgG in the neonatal rat
about
A major histocompatibility complex class I-like Fc receptor cloned from human placenta: possible role in transfer of immunoglobulin G from mother to fetusMHC class I-related neonatal Fc receptor for IgG is functionally expressed in monocytes, intestinal macrophages, and dendritic cellsFunctional reconstitution of human FcRn in Madin-Darby canine kidney cells requires co-expressed human beta 2-microglobulinMaternal LAMP/p55gagHIV-1 DNA immunization induces in utero priming and a long-lasting immune response in vaccinated neonatesThe neonatal Fc receptor, FcRn, as a target for drug delivery and therapyFcRn overexpression in transgenic mice results in augmented APC activity and robust immune response with increased diversity of induced antibodiesCharacterization of the rabbit neonatal Fc receptor (FcRn) and analyzing the immunophenotype of the transgenic rabbits that overexpresses FcRnEvidence for the sorting of endocytic vesicle contents during the receptor-mediated transport of IgG across the newborn rat intestineDistribution of immunoglobulin G receptors in the small intestine of the young ratpH-dependent binding of immunoglobulins to intestinal cells of the neonatal rat.Tryptophan- and dileucine-based endocytosis signals in the neonatal Fc receptor.Pharmacokinetic and pharmacodynamic effects of high-dose monoclonal antibody therapy in a rat model of immune thrombocytopeniaTissues Expression, Polymorphisms Identification of FcRn Gene and Its Relationship with Serum Classical Swine Fever Virus Antibody Level in Pigs.A single immunization with inactivated H1N1 influenza vaccine formulated with delta inulin adjuvant (Advax™) overcomes pregnancy-associated immune suppression and enhances passive neonatal protectionIgG transmitted from allergic mothers decreases allergic sensitization in breastfed offspring.Maternal antibodies: clinical significance, mechanism of interference with immune responses, and possible vaccination strategies.Electron tomography of late stages of FcRn-mediated antibody transcytosis in neonatal rat small intestineProtein binding by specific receptors on human placenta, murine placenta, and suckling murine intestine in relation to protein transport across these tissues.Abundant intracellular IgG in enterocytes and endoderm lacking FcRn.Anatomical, physiological, and experimental factors affecting the bioavailability of sc-administered large biotherapeuticsLigand valency affects transcytosis, recycling and intracellular trafficking mediated by the neonatal Fc receptorIntestinal barriers to water-soluble macromoleculesRecent advances using FcRn overexpression in transgenic animals to overcome impediments of standard antibody technologies to improve the generation of specific antibodies.Evidence that FcRn mediates the transplacental passage of maternal IgE in the form of IgG anti-IgE/IgE immune complexes.FcRn: The Architect Behind the Immune and Nonimmune Functions of IgG and Albumin.Overexpression of Bovine FcRn in Mice Enhances T-Dependent Immune Responses by Amplifying T Helper Cell Frequency and Germinal Center Enlargement in the Spleen.Placental Malaria: Decreased Transfer of Maternal Antibodies Directed to Plasmodium falciparum and Impact on the Incidence of Febrile Infections in Infants.Relative Contribution of Dengue IgG Antibodies Acquired during Gestation or Breastfeeding in Mediating Dengue Disease Enhancement and Protection in Type I Interferon Receptor-Deficient MiceMaturation of the Intestinal Epithelial Barrier in Neonatal Rats Coincides with Decreased FcRn Expression, Replacement of Vacuolated Enterocytes and Changed Blimp-1 Expression.Localization of neonatal Fc receptor for IgG in aggregated lymphoid nodules area in abomasum of Bactrian camels (Camelus bactrianus) of different agesFunctional assessment of antibody oxidation by native mass spectrometry.Human antibodies can cross guinea pig placenta and bind its neonatal Fc Receptor: implications for studying immune prophylaxis and therapy during pregnancyTranscytosis of staphylococcal superantigen toxins.Beta2-microglobulin-deficient mice are resistant to bullous pemphigoid.FcRn-mediated intestinal absorption of IgG anti-IgE/IgE immune complexes in mice.Targeting receptor-mediated endocytotic pathways with nanoparticles: rationale and advances.Loss of MYO5B in mice recapitulates Microvillus Inclusion Disease and reveals an apical trafficking pathway distinct to neonatal duodenum.Characterization of Vibrio cholerae outer membrane vesicles as a candidate vaccine for cholera.TGEV infection up-regulates FcRn expression via activation of NF-κB signaling.Bidirectional transepithelial IgG transport by a strongly polarized basolateral membrane Fcgamma-receptor.
P2860
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P2860
The mechanism of intestinal uptake and transcellular transport of IgG in the neonatal rat
description
1972 nî lūn-bûn
@nan
1972 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1972 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1972年の論文
@ja
1972年論文
@yue
1972年論文
@zh-hant
1972年論文
@zh-hk
1972年論文
@zh-mo
1972年論文
@zh-tw
1972年论文
@wuu
name
The mechanism of intestinal uptake and transcellular transport of IgG in the neonatal rat
@ast
The mechanism of intestinal uptake and transcellular transport of IgG in the neonatal rat
@en
type
label
The mechanism of intestinal uptake and transcellular transport of IgG in the neonatal rat
@ast
The mechanism of intestinal uptake and transcellular transport of IgG in the neonatal rat
@en
prefLabel
The mechanism of intestinal uptake and transcellular transport of IgG in the neonatal rat
@ast
The mechanism of intestinal uptake and transcellular transport of IgG in the neonatal rat
@en
P2860
P3181
P356
P1476
The mechanism of intestinal uptake and transcellular transport of IgG in the neonatal rat
@en
P2093
E. Anthony Jones
Thomas A. Waldmann
P2860
P304
P3181
P356
10.1172/JCI107116
P407
P577
1972-11-01T00:00:00Z