Macrocyclization by Ring-Closing Metathesis in the Total Synthesis of Natural Products: Reaction Conditions and Limitations
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Contemporary Strategies for the Synthesis of Tetrahydropyran Derivatives: Application to Total Synthesis of Neopeltolide, a Marine Macrolide Natural ProductSynthetic and structural studies on syringolin A and B reveal critical determinants of selectivity and potency of proteasome inhibitionRing-Expansion Approach to Medium-Sized Lactams and Analysis of Their Medicinal Lead-Like Properties.Total synthesis and structural revision of (+)-uprolide G acetate.Macrocyclization by nickel-catalyzed, ester-promoted, epoxide-alkyne reductive coupling: total synthesis of (-)-gloeosporone.Studies for the synthesis of marine natural productsAn expedient route to substituted furans via olefin cross-metathesis.Cross-metathesis-based approaches to heteroaromatics: combining catalysts for furan formation.An aldol-based build/couple/pair strategy for the synthesis of medium- and large-sized rings: discovery of macrocyclic histone deacetylase inhibitors.A diversity-oriented synthesis approach to macrocycles via oxidative ring expansion.Translating Nature's Library: The Bryostatins and Function-Oriented SynthesisSynthesis of (±)-tetrapetalone A-Me aglycon.Concise synthesis and biological assessment of (+)-neopeltolide and a 16-member stereoisomer library of 8,9-dehydroneopeltolide: identification of pharmacophoric elements.Macrocyclic drugs and synthetic methodologies toward macrocyclesSynthesis of macrocyclic natural products by catalyst-controlled stereoselective ring-closing metathesisFormation of a Novel Macrocyclic Alkaloid from the Unnatural Farnesyl Diphosphate Analogue Anilinogeranyl Diphosphate by 5-Epi-Aristolochene Synthase.Total Synthesis of Amphidinolide E and Amphidinolide E StereoisomersEvolution of a Unified Strategy for Complex Sesterterpenoids: Progress toward Astellatol and the Total Synthesis of (-)-Nitidasin.Manipulating micellar environments for enhancing transition metal-catalyzed cross-couplings in water at room temperatureSynthesis of 2-epi-amphidinolide E: an unexpected and highly selective C(2)inversion during an esterification reaction.The first transannular [4+3] cycloaddition reaction: synthesis of the ABCD ring structure of cortistatinsEvolution of the total synthesis of (-)-okilactomycin exploiting a tandem oxy-cope rearrangement/oxidation, a Petasis-Ferrier union/rearrangement, and ring-closing metathesis.A unified strategy for enantioselective total synthesis of cladiellin and briarellin diterpenes: total synthesis of briarellins E and F and the putative structure of alcyonin and revision of its structure assignment.Olefinic-lactone cyclizations to macrocycles.Bond formations by intermolecular and intramolecular trappings of acylketenes and their applications in natural product synthesis.Transition-metal-catalyzed laboratory-scale carbon-carbon bond-forming reactions of ethylenePrins-type macrocyclizations as an efficient ring-closing strategy in natural product synthesis.Chemical synthesis of the englerins.The chemistry of the polycyclic polyprenylated acylphloroglucinols.Efficient total synthesis of bioactive natural products: a personal record.Total syntheses of natural products containing spirocarbocycles.Synthetic Strategy and Anti-Tumor Activities of Macrocyclic Scaffolds Based on 4-Hydroxyproline.Efficient and selective formation of macrocyclic disubstituted Z alkenes by ring-closing metathesis (RCM) reactions catalyzed by Mo- or W-based monoaryloxide pyrrolide (MAP) complexes: applications to total syntheses of epilachnene, yuzu lactone, amRuthenium-Catalyzed Metathesis Cascade Reactions in Natural Products Synthesis.Total synthesis and biological evaluation of (-)-exiguolide analogues: importance of the macrocyclic backbone.A Shimizu non-aldol approach to the formal total synthesis of palmerolide A.Molecular editing and assessment of the cytotoxic properties of iejimalide and progeny.Synthesis and biological properties of the cytotoxic 14-membered macrolides aspergillide A and B.Probing the influence of an allylic methyl group in zearalenone analogues on binding to Hsp90.Novel Macrocyclic Amidinoureas: Potent Non-Azole Antifungals Active against Wild-Type and Resistant Candida Species.
P2860
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P2860
Macrocyclization by Ring-Closing Metathesis in the Total Synthesis of Natural Products: Reaction Conditions and Limitations
description
2006 nî lūn-bûn
@nan
2006 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Macrocyclization by Ring-Closi ...... ion Conditions and Limitations
@ast
Macrocyclization by Ring-Closi ...... ion Conditions and Limitations
@en
type
label
Macrocyclization by Ring-Closi ...... ion Conditions and Limitations
@ast
Macrocyclization by Ring-Closi ...... ion Conditions and Limitations
@en
prefLabel
Macrocyclization by Ring-Closi ...... ion Conditions and Limitations
@ast
Macrocyclization by Ring-Closi ...... ion Conditions and Limitations
@en
P3181
P356
P1476
Macrocyclization by Ring-Closi ...... ion Conditions and Limitations
@en
P2093
Ana Gradillas
Javier Pérez-Castells
P304
P3181
P356
10.1002/ANIE.200600641
P407
P577
2006-09-18T00:00:00Z