An siRNA-based functional genomics screen for the identification of regulators of ciliogenesis and ciliopathy genes
about
Ciliogenesis and the DNA damage response: a stressful relationshipA primer on the mouse basal bodySpecialized Cilia in Mammalian Sensory SystemsThe Cilium: Cellular Antenna and Central Processing UnitIsolated and Syndromic Retinal Dystrophy Caused by Biallelic Mutations in RCBTB1, a Gene Implicated in UbiquitinationAxial Spondylometaphyseal Dysplasia Is Caused by C21orf2 MutationsMutations in PIH1D3 Cause X-Linked Primary Ciliary Dyskinesia with Outer and Inner Dynein Arm DefectsAn organelle-specific protein landscape identifies novel diseases and molecular mechanismsIFT81 as a Candidate Gene for Nonsyndromic Retinal Degeneration.Structural and Functional Recovery of Sensory Cilia in C. elegans IFT Mutants upon Aging.Systematic high-content genome-wide RNAi screens of endothelial cell migration and morphology.Identification and Correction of Mechanisms Underlying Inherited Blindness in Human iPSC-Derived Optic Cups.Sfr1, a Tetrahymena thermophila Sfi1 Repeat Protein, Modulates the Production of Cortical Row Basal Bodies.GEMC1 is a critical regulator of multiciliated cell differentiation.Centriole splitting caused by loss of the centrosomal linker protein C-NAP1 reduces centriolar satellite density and impedes centrosome amplification.Centrosome positioning in non-dividing cells.A non-canonical function of Plk4 in centriolar satellite integrity and ciliogenesis through PCM1 phosphorylation.Screen-based identification and validation of four new ion channels as regulators of renal ciliogenesisRegulation of centriolar satellite integrity and its physiologyRetinal Degeneration and Regeneration-Lessons From Fishes and Amphibians.Motile and non-motile cilia in human pathology: from function to phenotypes.Fifteen years of research on oral-facial-digital syndromes: from 1 to 16 causal genes.Spatially and temporally regulating translation via mRNA-binding proteins in cellular and neuronal function.Role of primary cilia in non-dividing and post-mitotic cells.Genes and molecular pathways underpinning ciliopathies.Characterizing the morbid genome of ciliopathies.Bardet-Biedl Syndrome as a Chaperonopathy: Dissecting the Major Role of Chaperonin-Like BBS Proteins (BBS6-BBS10-BBS12).Expanding the genetic architecture and phenotypic spectrum in the skeletal ciliopathies.Whole-exome sequencing reveals POC5 as a novel gene associated with autosomal recessive retinitis pigmentosa.Novel genes associated with amyotrophic lateral sclerosis: diagnostic and clinical implications.Microtubule stabilization drives 3D centrosome migration to initiate primary ciliogenesis.A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies.RNA Biology in Retinal Development and Disease.Signaling through the Primary Cilium.Axial spondylometaphyseal dysplasia is also caused by NEK1 mutations.A biallelic 36-bp insertion in PIBF1 is associated with Joubert syndrome.Ganetespib limits ciliation and cystogenesis in autosomal-dominant polycystic kidney disease (ADPKD).Elsahy-Waters syndrome is caused by biallelic mutations in CDH11.Homozygous variant in C21orf2 in a case of Jeune syndrome with severe thoracic involvement: Extending the phenotypic spectrum.Targeted deletion of the AAA-ATPase Ruvbl1 in mice disrupts ciliary integrity and causes renal disease and hydrocephalus.
P2860
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P2860
An siRNA-based functional genomics screen for the identification of regulators of ciliogenesis and ciliopathy genes
description
2015 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2015
@ast
im August 2015 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
wetenschappelijk artikel (gepubliceerd op 2015/08/01)
@nl
наукова стаття, опублікована в серпні 2015
@uk
مقالة علمية (نشرت في أغسطس 2015)
@ar
name
An siRNA-based functional geno ...... iogenesis and ciliopathy genes
@ast
An siRNA-based functional geno ...... iogenesis and ciliopathy genes
@en
An siRNA-based functional geno ...... iogenesis and ciliopathy genes
@en-gb
type
label
An siRNA-based functional geno ...... iogenesis and ciliopathy genes
@ast
An siRNA-based functional geno ...... iogenesis and ciliopathy genes
@en
An siRNA-based functional geno ...... iogenesis and ciliopathy genes
@en-gb
prefLabel
An siRNA-based functional geno ...... iogenesis and ciliopathy genes
@ast
An siRNA-based functional geno ...... iogenesis and ciliopathy genes
@en
An siRNA-based functional geno ...... iogenesis and ciliopathy genes
@en-gb
P2093
P2860
P50
P3181
P356
P1154
2-s2.0-84938681395
P1433
P1476
An siRNA-based functional geno ...... iogenesis and ciliopathy genes
@en
P2093
A James Barkovich
A Micheil Innes
Aizeddin A Mhanni
Albert E Chudley
Andrew R Webster
Bernard N Chodirker
Chandree L Beaulieu
Chris F Inglehearn
Clem Donahue
Colin A Johnson
P2860
P2888
P304
P3181
P356
10.1038/NCB3201
P50
P5530
P577
2015-07-13T00:00:00Z
P5875
P6179
1019262476