Cooperative binding of phosphorylated DevR to upstream sites is necessary and sufficient for activation of the Rv3134c-devRS operon in Mycobacterium tuberculosis: implication in the induction of DevR target genes.
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Co-expression of DevR and DevR(N)-Aph proteins is associated with hypoxic adaptation defect and virulence attenuation of Mycobacterium tuberculosisMycobacterium tuberculosis transcriptional adaptation, growth arrest and dormancy phenotype development is triggered by vitamin CInteraction of DevR with multiple binding sites synergistically activates divergent transcription of narK2-Rv1738 genes in Mycobacterium tuberculosisThe Mycobacterium tuberculosis DosR regulon assists in metabolic homeostasis and enables rapid recovery from nonrespiring dormancyMycobacterium tuberculosis DevR/DosR Dormancy Regulator Activation Mechanism: Dispensability of Phosphorylation, Cooperativity and Essentiality of α10 HelixDeterminants outside the DevR C-terminal domain are essential for cooperativity and robust activation of dormancy genes in Mycobacterium tuberculosis.The DosS-DosT/DosR Mycobacterial Sensor System.DevR (DosR) mimetic peptides impair transcriptional regulation and survival of Mycobacterium tuberculosis under hypoxia by inhibiting the autokinase activity of DevS sensor kinase.HspX vaccination and role in virulence in the guinea pig model of tuberculosis.Appropriate DevR (DosR)-mediated signaling determines transcriptional response, hypoxic viability and virulence of Mycobacterium tuberculosisDecoding ChIP-seq with a double-binding signal refines binding peaks to single-nucleotides and predicts cooperative interaction.Mycobacterium tuberculosis response regulators, DevR and NarL, interact in vivo and co-regulate gene expression during aerobic nitrate metabolismComprehensive insights into Mycobacterium tuberculosis DevR (DosR) regulon activation switch.Adaptation to environmental stimuli within the host: two-component signal transduction systems of Mycobacterium tuberculosis.MprA and DosR coregulate a Mycobacterium tuberculosis virulence operon encoding Rv1813c and Rv1812c.Expression, maturation and turnover of DrrS, an unusually stable, DosR regulated small RNA in Mycobacterium tuberculosisCharacterization of a cAMP responsive transcription factor, Cmr (Rv1675c), in TB complex mycobacteria reveals overlap with the DosR (DevR) dormancy regulon.DevR-mediated adaptive response in Mycobacterium tuberculosis H37Ra: links to asparagine metabolismCooperative stabilization of Mycobacterium tuberculosis rrnAP3 promoter open complexes by RbpA and CarD.RegAnalyst: a web interface for the analysis of regulatory motifs, networks and pathways.tRNA-mediated codon-biased translation in mycobacterial hypoxic persistence.Mycobacterial Dormancy Systems and Host Responses in Tuberculosis.The residue threonine 82 of DevR (DosR) is essential for DevR activation and function in Mycobacterium tuberculosis despite its atypical location.Identification of the regulator gene responsible for the acetone-responsive expression of the binuclear iron monooxygenase gene cluster in mycobacteria.Components of the Rv0081-Rv0088 locus, which encodes a predicted formate hydrogenlyase complex, are coregulated by Rv0081, MprA, and DosR in Mycobacterium tuberculosis.OsdR of Streptomyces coelicolor and the Dormancy Regulator DevR of Mycobacterium tuberculosis Control Overlapping Regulons.Essentiality of DevR/DosR interaction with SigA for the dormancy survival program in Mycobacterium tuberculosis.The α10 helix of DevR, the Mycobacterium tuberculosis dormancy response regulator, regulates its DNA binding and activity.Unique Regulation of the DosR Regulon in the Beijing Lineage of Mycobacterium tuberculosis.DosR-regulon genes induction in Mycobacterium bovis BCG under aerobic conditions.Analysis of DevR regulated genes in Mycobacterium tuberculosis.Powerful induction of divergent tgs1-Rv3131 genes in Mycobacterium tuberculosis is mediated by DevR interaction with a high-affinity site and an adjacent cryptic low-affinity siteTarget DNA stabilizes Mycobacterium tuberculosis DevR/DosR phosphorylation by the full-length oxygen sensors DevS/DosS and DosT.Regulation of Three Virulence Strategies of Mycobacterium tuberculosis: A Success Story.Multifaceted remodeling by vitamin C boosts sensitivity of Mycobacterium tuberculosis subpopulations to combination treatment by anti-tubercular drugs.DevS/DosS sensor is bifunctional and its phosphatase activity precludes aerobic DevR/DosR regulon expression in Mycobacterium tuberculosis.Acetylation of lysine 182 inhibits the ability of Mycobacterium tuberculosis DosR to bind DNA and regulate gene expression during hypoxia.K182G substitution in DevR or C8G mutation in the Dev box impairs protein-DNA interaction and abrogates DevR-mediated gene induction in Mycobacterium tuberculosis
P2860
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P2860
Cooperative binding of phosphorylated DevR to upstream sites is necessary and sufficient for activation of the Rv3134c-devRS operon in Mycobacterium tuberculosis: implication in the induction of DevR target genes.
description
2008 nî lūn-bûn
@nan
2008 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի մարտին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Cooperative binding of phospho ...... nduction of DevR target genes.
@ast
Cooperative binding of phospho ...... nduction of DevR target genes.
@en
type
label
Cooperative binding of phospho ...... nduction of DevR target genes.
@ast
Cooperative binding of phospho ...... nduction of DevR target genes.
@en
prefLabel
Cooperative binding of phospho ...... nduction of DevR target genes.
@ast
Cooperative binding of phospho ...... nduction of DevR target genes.
@en
P2860
P3181
P356
P1476
Cooperative binding of phospho ...... nduction of DevR target genes.
@en
P2093
Jaya Sivaswami Tyagi
Santosh Chauhan
P2860
P304
P3181
P356
10.1128/JB.01308-07
P407
P577
2008-03-21T00:00:00Z