NKX6.1 promotes PDX-1-induced liver to pancreatic β-cells reprogramming.
about
Ectopic PDX-1 expression directly reprograms human keratinocytes along pancreatic insulin-producing cells fateCurrent status of immunomodulatory and cellular therapies in preclinical and clinical islet transplantation.Nkx6.1 controls a gene regulatory network required for establishing and maintaining pancreatic Beta cell identity.Transcription factors that convert adult cell identity are differentially polycomb repressedC-Abl inhibitor imatinib enhances insulin production by β cells: c-Abl negatively regulates insulin production via interfering with the expression of NKx2.2 and GLUT-2.Human liver cells expressing albumin and mesenchymal characteristics give rise to insulin-producing cellsCombinatorial treatment of bone marrow stem cells and stromal cell-derived factor 1 improves glycemia and insulin production in diabetic mice.Nkx2.2 repressor complex regulates islet β-cell specification and prevents β-to-α-cell reprogramming.Progenitor potential of nkx6.1-expressing cells throughout zebrafish life and during beta cell regenerationPAX4 Gene Transfer Induces α-to-β Cell Phenotypic Conversion and Confers Therapeutic Benefits for Diabetes Treatment.Pancreatic Transdifferentiation and Glucose-Regulated Production of Human Insulin in the H4IIE Rat Liver Cell Line.Reprogramming adult human dermal fibroblasts to islet-like cells by epigenetic modification coupled to transcription factor modulation.Grg3/TLE3 and Grg1/TLE1 induce monohormonal pancreatic β-cells while repressing α-cell functions.Stem cell-based approaches for the treatment of diabetes.The therapeutic potential of GPR119 agonists for type 2 diabetes.Restoring insulin production for type 1 diabetes.Directed differentiation of progenitor cells towards an islet-cell phenotype.The use of β-cell transcription factors in engineering artificial β cells from non-pancreatic tissue.How to make insulin-producing pancreatic β cells for diabetes treatment.The temporal and hierarchical control of transcription factors-induced liver to pancreas transdifferentiation.Pancreatic and duodenal homeobox gene 1 (Pdx1) down-regulates hepatic transcription factor 1 alpha (HNF1α) expression during reprogramming of human hepatic cells into insulin-producing cells.Generation of Islet-like Cell Aggregates from Human Adipose Tissue-derived Stem Cells by Lentiviral Overexpression of PDX-1Buffalo alpha S1-casein gene 5'-flanking region and its interspecies comparison.Regenerating β cells of the pancreas - potential developments in diabetes treatment.The functional and molecular characterisation of human embryonic stem cell-derived insulin-positive cells compared with adult pancreatic beta cells.
P2860
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P2860
NKX6.1 promotes PDX-1-induced liver to pancreatic β-cells reprogramming.
description
2010 nî lūn-bûn
@nan
2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
NKX6.1 promotes PDX-1-induced liver to pancreatic β-cells reprogramming.
@ast
NKX6.1 promotes PDX-1-induced liver to pancreatic β-cells reprogramming.
@en
type
label
NKX6.1 promotes PDX-1-induced liver to pancreatic β-cells reprogramming.
@ast
NKX6.1 promotes PDX-1-induced liver to pancreatic β-cells reprogramming.
@en
prefLabel
NKX6.1 promotes PDX-1-induced liver to pancreatic β-cells reprogramming.
@ast
NKX6.1 promotes PDX-1-induced liver to pancreatic β-cells reprogramming.
@en
P2093
P3181
P356
P1476
NKX6.1 promotes PDX-1-induced liver to pancreatic β-cells reprogramming.
@en
P2093
Dana Berneman
Irit Meivar-Levy
Itzhak H Rachmut
Kfir Molakandov
Sarah Ferber
Shiraz Gefen-Halevi
P304
P3181
P356
10.1089/CELL.2010.0030
P577
2010-12-01T00:00:00Z