Drug specificity and intestinal membrane localization of human organic cation transporters (OCT).
about
How drugs get into cells: tested and testable predictions to help discriminate between transporter-mediated uptake and lipoidal bilayer diffusionPharmacogenetics in type 2 diabetes: influence on response to oral hypoglycemic agentsOATPs, OATs and OCTs: the organic anion and cation transporters of the SLCO and SLC22A gene superfamiliesRole of the plasma membrane transporter of organic cations OCT1 and its genetic variants in modern liver pharmacologycis -Diammine(pyridine)chloroplatinum(II), a monofunctional platinum(II) antitumor agent: Uptake, structure, function, and prospectsMetformin and the gastrointestinal tractHepatocyte nuclear factor 1 regulates the expression of the organic cation transporter 1 via binding to an evolutionary conserved region in intron 1 of the OCT1 geneMembrane transporters in drug developmentMembrane transporters as mediators of Cisplatin effects and side effects.Common drugs inhibit human organic cation transporter 1 (OCT1)-mediated neurotransmitter uptake.Gene expression profiling of transporters in the solute carrier and ATP-binding cassette superfamilies in human eye substructures.Variants in Pharmacokinetic Transporters and Glycemic Response to Metformin: A Metgen Meta-Analysis.Xenobiotic, bile acid, and cholesterol transporters: function and regulation.An update on the pharmacogenomics of metformin: progress, problems and potential.Uptake of pramipexole by human organic cation transporters.Nucleoside transporter proteins as biomarkers of drug responsiveness and drug targets.Association of Organic Cation Transporter 1 With Intolerance to Metformin in Type 2 Diabetes: A GoDARTS Study.Targeted disruption of organic cation transporter 3 attenuates the pharmacologic response to metforminDrug Transporters and Na+/H+ Exchange Regulatory Factor PSD-95/Drosophila Discs Large/ZO-1 ProteinsAssessment of the Relation between the Expression of Oxaliplatin Transporters in Colorectal Cancer and Response to FOLFOX-4 Adjuvant Chemotherapy: A Case Control StudyRole of a Hydrophobic Pocket in Polyamine Interactions with the Polyspecific Organic Cation Transporter OCT3Nonoisotopic assay for the presynaptic choline transporter reveals capacity for allosteric modulation of choline uptake.Polyamine transport by the polyspecific organic cation transporters OCT1, OCT2, and OCT3Metformin pathways: pharmacokinetics and pharmacodynamicsThe effect of dipyridamole on the pharmacokinetics of metformin: a randomized crossover study in healthy volunteers.Substrate-dependent ligand inhibition of the human organic cation transporter OCT2.Organic cation transporter 1 (OCT1/mOct1) is localized in the apical membrane of Caco-2 cell monolayers and enterocytes.Metformin transport by a newly cloned proton-stimulated organic cation transporter (plasma membrane monoamine transporter) expressed in human intestine.Organic cation transporter 1 variants and gastrointestinal side effects of metformin in patients with Type 2 diabetes.Trimethoprim-metformin interaction and its genetic modulation by OCT2 and MATE1 transporters.Organic cation transporters are determinants of oxaliplatin cytotoxicity.Pharmacogenetics and personalized treatment of type 2 diabetesInvolvement of organic cation transporter 3 (Oct3/Slc22a3) in the bioavailability and pharmacokinetics of antidiabetic metformin in mice.Multiple mechanisms of ligand interaction with the human organic cation transporter, OCT2Drug transporter pharmacogenetics in nucleoside-based therapies.Transporters that translocate nucleosides and structural similar drugs: structural requirements for substrate recognition.Phase 0 and phase III transport in various organs: combined concept of phases in xenobiotic transport and metabolism.A Comprehensive Review of Drug-Drug Interactions with Metformin.Transporter-Mediated Disposition of Opioids: Implications for Clinical Drug Interactions.Evidence-based prioritisation and enrichment of genes interacting with metformin in type 2 diabetes.
P2860
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P2860
Drug specificity and intestinal membrane localization of human organic cation transporters (OCT).
description
2005 nî lūn-bûn
@nan
2005 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Drug specificity and intestina ...... nic cation transporters (OCT).
@ast
Drug specificity and intestina ...... nic cation transporters (OCT).
@en
type
label
Drug specificity and intestina ...... nic cation transporters (OCT).
@ast
Drug specificity and intestina ...... nic cation transporters (OCT).
@en
prefLabel
Drug specificity and intestina ...... nic cation transporters (OCT).
@ast
Drug specificity and intestina ...... nic cation transporters (OCT).
@en
P2093
P3181
P1476
Drug specificity and intestina ...... nic cation transporters (OCT).
@en
P2093
Hermann Koepsell
Johanna Müller
Katrin S Lips
Linda Metzner
Matthias Brandsch
Reinhard H H Neubert
P304
P3181
P356
10.1016/J.BCP.2005.09.011
P407
P577
2005-11-02T00:00:00Z