Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes
about
A conditional knockout resource for the genome-wide study of mouse gene functionPrenatal folic acid treatment suppresses acrania and meroanencephaly in mice mutant for the Cart1 homeobox geneTumor formation and inactivation of RIZ1, an Rb-binding member of a nuclear protein-methyltransferase superfamilyTargeted gene disruption of Hsp70-2 results in failed meiosis, germ cell apoptosis, and male infertilityElastin is an essential determinant of arterial morphogenesisAcid sphingomyelinase deficient mice: a model of types A and B Niemann-Pick diseaseDefective adipocyte differentiation in mice lacking the C/EBPbeta and/or C/EBPdelta gene.Asthenozoospermia in mice with targeted deletion of the sperm mitochondrion-associated cysteine-rich protein (Smcp) geneFliih, a gelsolin-related cytoskeletal regulator essential for early mammalian embryonic developmentDisruption of PPT1 or PPT2 causes neuronal ceroid lipofuscinosis in knockout miceMetaxin, a gene contiguous to both thrombospondin 3 and glucocerebrosidase, is required for embryonic development in the mouse: implications for Gaucher diseaseImmunoglobulin D-deficient mice can mount normal immune responses to thymus-independent and -dependent antigensTransforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early deathGsh-4 encodes a LIM-type homeodomain, is expressed in the developing central nervous system and is required for early postnatal survivalA nonredundant role for mouse Serpinb3a in the induction of mucus production in asthmaSelf-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3Noggin-mediated antagonism of BMP signaling is required for growth and patterning of the neural tube and somiteGerm-line transmission of a planned alteration made in a hypoxanthine phosphoribosyltransferase gene by homologous recombination in embryonic stem cellsPrecision editing of large animal genomesTargeted disruption of a human interferon-inducible gene detected by secretion of human growth hormoneNewer gene editing technologies toward HIV gene therapyTwo hypervariable minisatellite DNA binding proteinsTargeted transgenesisMolecular cloning of the human XRCC1 gene, which corrects defective DNA strand break repair and sister chromatid exchangeFacile methods for generating human somatic cell gene knockouts using recombinant adeno-associated virusesA targeted mutation in the murine gene encoding the high density lipoprotein (HDL) receptor scavenger receptor class B type I reveals its key role in HDL metabolismInduction of homologous recombination in mammalian chromosomes by using the I-SceI system of Saccharomyces cerevisiaeA mammalian model for Laron syndrome produced by targeted disruption of the mouse growth hormone receptor/binding protein gene (the Laron mouse)Disruption of the murine nuclear factor I-A gene (Nfia) results in perinatal lethality, hydrocephalus, and agenesis of the corpus callosumRegulatory divergence modifies limb length between mammalsHepatic cholesterol metabolism and resistance to dietary cholesterol in LXRbeta-deficient miceTransfer of single gene-containing long terminal repeats into the genome of mammalian cells by a retroviral vector carrying the cre gene and the loxP siteEarly embryonic lethality of mice lacking the essential protein SNEVA general cloning system to selectively isolate any eukaryotic or prokaryotic genomic region in yeastGene targeting in mosquito cells: a demonstration of 'knockout' technology in extrachromosomal gene arraysIdentification of cardiac malformations in mice lacking Ptdsr using a novel high-throughput magnetic resonance imaging techniqueGene Targeting Using Homologous Recombination in Embryonic Stem Cells: The Future for Behavior Genetics?Origins of Programmable Nucleases for Genome EngineeringFrom Gene Targeting to Genome Editing: Transgenic animals applications and beyondAnalysis of enamel development using murine model systems: approaches and limitations
P2860
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P2860
Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes
description
1988 nî lūn-bûn
@nan
1988 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1988 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
name
Disruption of the proto-oncoge ...... ations to non-selectable genes
@ast
Disruption of the proto-oncoge ...... ations to non-selectable genes
@en
type
label
Disruption of the proto-oncoge ...... ations to non-selectable genes
@ast
Disruption of the proto-oncoge ...... ations to non-selectable genes
@en
prefLabel
Disruption of the proto-oncoge ...... ations to non-selectable genes
@ast
Disruption of the proto-oncoge ...... ations to non-selectable genes
@en
P2093
P3181
P356
P1433
P1476
Disruption of the proto-oncoge ...... ations to non-selectable genes
@en
P2093
Capecchi MR
Mansour SL
P2888
P304
P3181
P356
10.1038/336348A0
P407
P577
1988-11-24T00:00:00Z
P5875
P6179
1024391427