An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells
about
Systematic identification of mRNAs recruited to argonaute 2 by specific microRNAs and corresponding changes in transcript abundanceComputational identification of Drosophila microRNA genesPlanting the seeds of a new paradigmDBR1 siRNA inhibition of HIV-1 replication.Evolutionary connection between the catalytic subunits of DNA-dependent RNA polymerases and eukaryotic RNA-dependent RNA polymerases and the origin of RNA polymerasesHsp90 cochaperones p23 and FKBP4 physically interact with hAgo2 and activate RNA interference-mediated silencing in mammalian cellsInteraction of human T-cell lymphotropic virus type I Rex protein with Dicer suppresses RNAi silencingExportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAsRibonuclease activity and RNA binding of recombinant human DicerOverexpression of exportin 5 enhances RNA interference mediated by short hairpin RNAs and microRNAs.Transcriptional silencing of a transgene by RNAi in the soma of C. elegansAlternative initiation and splicing in dicer gene expression in human breast cellsStable suppression of gene expression by RNAi in mammalian cellsMicroRNA maturation: stepwise processing and subcellular localization.Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAsUncoupling of RNAi from active translation in mammalian cells.Small interfering RNAs containing full 2'-O-methylribonucleotide-modified sense strands display Argonaute2/eIF2C2-dependent activity.miRNP:mRNA association in polyribosomes in a human neuronal cell line.Formation of Tap/NXT1 heterodimers activates Tap-dependent nuclear mRNA export by enhancing recruitment to nuclear pore complexesHuman Dicer preferentially cleaves dsRNAs at their termini without a requirement for ATPFunctional replacement of Trypanosoma brucei Argonaute by the human slicer Argonaute2Cleavage of the siRNA passenger strand during RISC assembly in human cellsSpecific double-stranded RNA interference in undifferentiated mouse embryonic stem cellsKaposi's sarcoma-associated herpesvirus expresses an array of viral microRNAs in latently infected cellsA single Argonaute protein mediates both transcriptional and posttranscriptional silencing in Schizosaccharomyces pombeDistinct roles for Argonaute proteins in small RNA-directed RNA cleavage pathwaysRNA interference: biology, mechanism, and applicationsIdentification of microRNAs and other small regulatory RNAs using cDNA library sequencingGenomic screening with RNAi: results and challengesThe role of dicer in DNA damage repairMicroRNA biogenesis: there's more than one way to skin a catIdentification of specific let-7 microRNA binding complexes in Caenorhabditis elegansThe RNA-induced silencing complex: a versatile gene-silencing machineShhh! Silencing by microRNA-155Small silencing RNAs: an expanding universemiRNPs: a novel class of ribonucleoproteins containing numerous microRNAsThe microRNAs of Caenorhabditis elegansExtensive post-transcriptional regulation of microRNAs and its implications for cancerMicroRNAs in plantsGene therapy in clinical medicine
P2860
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P2860
An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells
description
2000 nî lūn-bûn
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2000 թուականի Մարտին հրատարակուած գիտական յօդուած
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2000年の論文
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2000年論文
@yue
2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年论文
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name
An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells
@ast
An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells
@en
type
label
An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells
@ast
An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells
@en
prefLabel
An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells
@ast
An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells
@en
P2093
P921
P3181
P356
P1433
P1476
An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells
@en
P2093
P2888
P3181
P356
10.1038/35005107
P407
P577
2000-03-16T00:00:00Z
P5875
P6179
1053082190