Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways
about
A role for Alström syndrome protein, alms1, in kidney ciliogenesis and cellular quiescenceThe dynamic cilium in human diseasesA complex of BBS1 and NPHP7 is required for cilia motility in zebrafishExome capture reveals ZNF423 and CEP164 mutations, linking renal ciliopathies to DNA damage response signalingDissection of epistasis in oligogenic Bardet-Biedl syndromePolycystin-1 regulates the stability and ubiquitination of transcription factor Jade-1Uromodulin is expressed in renal primary cilia and UMOD mutations result in decreased ciliary uromodulin expressionMyristoylated Naked2 antagonizes Wnt-beta-catenin activity by degrading Dishevelled-1 at the plasma membraneIndividuals with mutations in XPNPEP3, which encodes a mitochondrial protein, develop a nephronophthisis-like nephropathyBBS proteins interact genetically with the IFT pathway to influence SHH-related phenotypesNephrocystins and MKS proteins interact with IFT particle and facilitate transport of selected ciliary cargosNephrocystin-3 is required for ciliary function in zebrafish embryosLoss of nephrocystin-3 function can cause embryonic lethality, Meckel-Gruber-like syndrome, situs inversus, and renal-hepatic-pancreatic dysplasiaNEK1 mutations cause short-rib polydactyly syndrome type majewskiThe centrosomal protein nephrocystin-6 is mutated in Joubert syndrome and activates transcription factor ATF4Increased expression of secreted frizzled-related protein 4 in polycystic kidneysCiliary and centrosomal defects associated with mutation and depletion of the Meckel syndrome genes MKS1 and MKS3Protein kinase A-mediated 14-3-3 association impedes human Dapper1 to promote dishevelled degradationNephronophthisisDisruption of Mks1 localization to the mother centriole causes cilia defects and developmental malformations in Meckel-Gruber syndromeWnt/beta-catenin signaling: components, mechanisms, and diseasesThe role of primary cilia in neuronal functionThe primary cilium as a cellular signaling center: lessons from diseaseMechanisms of nephronophthisis and related ciliopathiesJade-1 inhibits Wnt signalling by ubiquitylating beta-catenin and mediates Wnt pathway inhibition by pVHLHEF1-dependent Aurora A activation induces disassembly of the primary ciliumThe cilia-regulated proteasome and its role in the development of ciliopathies and cancerCilia in autophagy and cancerRole of the Polycystins in Cell Migration, Polarity, and Tissue MorphogenesisA polycystin-centric view of cyst formation and disease: the polycystins revisitedCilia in vertebrate development and diseaseThe kidney and planar cell polarity.Understanding ciliated epithelia: the power of XenopusWnt and planar cell polarity signaling in cystic renal diseasePrimary cilia in the developing and mature brainInositol polyphosphate 5-phosphatases; new players in the regulation of cilia and ciliopathiesCoordination of kidney organogenesis by Wnt signalingSpectrum of clinical diseases caused by disorders of primary ciliaCompartments within a compartment: what C. elegans can tell us about ciliary subdomain composition, biogenesis, function, and diseaseScrutinizing ciliopathies by unraveling ciliary interaction networks
P2860
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P2860
Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways
description
2005 nî lūn-bûn
@nan
2005 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Inversin, the gene product mut ...... between Wnt signaling pathways
@ast
Inversin, the gene product mut ...... between Wnt signaling pathways
@en
type
label
Inversin, the gene product mut ...... between Wnt signaling pathways
@ast
Inversin, the gene product mut ...... between Wnt signaling pathways
@en
prefLabel
Inversin, the gene product mut ...... between Wnt signaling pathways
@ast
Inversin, the gene product mut ...... between Wnt signaling pathways
@en
P2093
P2860
P50
P3181
P356
P1433
P1476
Inversin, the gene product mut ...... between Wnt signaling pathways
@en
P2093
Andreas Jenny
Athina Ganner
Axel Bullerkotte
Bozena Polok
Corinna Krönig
Joachim Gloy
Marek Mlodzik
Mikhail Bashkurov
Olga A Cabello
P2860
P2888
P304
P3181
P356
10.1038/NG1552
P407
P577
2005-04-24T00:00:00Z
P5875
P6179
1038593550