Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility - Wikidata - awgldk - TriplyDB

Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility

Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility

http://www.wikidata.org/entity/Q29614872

about

Systematic association mapping identifies NELL1 as a novel IBD disease gene Intestinal DMBT1 expression is modulated by Crohn's disease-associated IL23R variants and by a DMBT1 variant which influences binding of the transcription factors CREB1 and ATF-2 Evidence for significant overlap between common risk variants for Crohn's disease and ankylosing spondylitis Crohn's disease and early exposure to domestic refrigeration Death and resurrection of the human IRGM gene Central role of the gut epithelial barrier in the pathogenesis of chronic intestinal inflammation: lessons learned from animal models and human genetics Human genetics and genomics a decade after the release of the draft sequence of the human genome Autophagy gene variant IRGM -261T contributes to protection from tuberculosis caused by Mycobacterium tuberculosis but not by M. africanum strains Interaction of Crohn's disease susceptibility genes in an Australian paediatric cohort Molecular reclassification of Crohn's disease by cluster analysis of genetic variants Interpretation of genetic association studies: markers with replicated highly significant odds ratios may be poor classifiers Mycobacteria in Crohn’s disease: how innate immune deficiency may result in chronic inflammation Replication of Colonic Crohn's Disease Mucosal Escherichia coli Isolates within Macrophages and Their Susceptibility to Antibiotics Independent and population-specific association of risk variants at the IRGM locus with Crohn's disease Recent Insights Into the Genetics of Inflammatory Bowel Disease Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease Involvement of mycobacterium avium subspecies paratuberculosis in TNF-α production from macrophage: Possible link between MAP and immune response in Crohnʼs disease GWAS of 126,559 individuals identifies genetic variants associated with educational attainment Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls High prevalence of viable Mycobacterium avium subspecies paratuberculosis in Crohn's disease Genetics and visceral leishmaniasis: of mice and man NKX2-3 and IRGM variants are associated with disease susceptibility to IBD in Eastern European patients Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci Shared and distinct genetic variants in type 1 diabetes and celiac disease The emerging role of IL-17 in the pathogenesis of psoriasis: preclinical and clinical findings Association of linear growth impairment in pediatric Crohn's disease and a known height locus: a pilot study Human IRGM regulates autophagy and cell-autonomous immunity functions through mitochondria Endoplasmic reticulum stress and the inflammatory basis of metabolic disease Ulcerative colitis-risk loci on chromosomes 1p36 and 12q15 found by genome-wide association study Diverse genome-wide association studies associate the IL12/IL23 pathway with Crohn Disease Autophagy and pattern recognition receptors in innate immunity Autophagy in immunity against mycobacterium tuberculosis: a model system to dissect immunological roles of autophagy Loci on 20q13 and 21q22 are associated with pediatric-onset inflammatory bowel disease Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region Genome-wide association study for Crohn's disease in the Quebec Founder Population identifies multiple validated disease loci The clearance of dying cells: table for two Roles of Autophagy and Autophagy-Related Proteins in Antifungal Immunity Protein tyrosine phosphatase non-receptor type 2 and inflammatory bowel disease Mechanisms of Microbe-Host Interaction in Crohn's Disease: Dysbiosis vs. Pathobiont Selection

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P2860

Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility

http://www.wikidata.org/entity/Q29614872

description

2007 nî lūn-bûn

@nan

2007 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2007 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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name

Sequence variants in the autop ...... Crohn's disease susceptibility

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Sequence variants in the autop ...... Crohn's disease susceptibility

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type

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Sequence variants in the autop ...... Crohn's disease susceptibility

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Sequence variants in the autop ...... Crohn's disease susceptibility

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Sequence variants in the autop ...... Crohn's disease susceptibility

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Sequence variants in the autop ...... Crohn's disease susceptibility

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P1433

Nature Genetics

P1476

Sequence variants in the autop ...... Crohn's disease susceptibility

@en

P2093

Catherine E Todhunter

http://www.w3.org/2001/XMLSchema#string

Charlie W Lees

http://www.w3.org/2001/XMLSchema#string

Claire Bryan

http://www.w3.org/2001/XMLSchema#string

Clive M Onnie

http://www.w3.org/2001/XMLSchema#string

David Strachan

http://www.w3.org/2001/XMLSchema#string

Denis A Burke

http://www.w3.org/2001/XMLSchema#string

Derek P Jewell

http://www.w3.org/2001/XMLSchema#string

Dianne Soars

http://www.w3.org/2001/XMLSchema#string

Elaine R Nimmo

http://www.w3.org/2001/XMLSchema#string

Fraser R Cummings

http://www.w3.org/2001/XMLSchema#string

P2860

The interferon-inducible p47 (IRG) GTPases in vertebrates: loss of the cell autonomous resistance mechanism in the human lineage.

A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes

Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis

A large-scale genetic association study confirms IL12B and leads to the identification of IL23R as psoriasis-risk genes

Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

A genome-wide association study identifies IL23R as an inflammatory bowel disease gene

Novel Crohn disease locus identified by genome-wide association maps to a gene desert on 5p13.1 and modulates expression of PTGER4

NKX2.3 is required for MAdCAM-1 expression and homing of lymphocytes in spleen and mucosa-associated lymphoid tissue

Inactivation of LRG-47 and IRG-47 reveals a family of interferon gamma-inducible genes with essential, pathogen-specific roles in resistance to infection

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830-832

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scholarly article

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314978

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10.1038/NG2061

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P433

7

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39

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Natalie J. Prescott

Christopher G. Mathew

Roland G. Roberts

Jeffrey C Barrett

Alastair Forbes

Richard D Bagnall

Carl A Anderson

P577

2007-06-06T00:00:00Z

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6283081

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1032812994

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17554261

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Crohn's disease

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2628541

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