Centrioles, centrosomes, and cilia in health and disease
about
Centrosome dysfunction contributes to chromosome instability, chromoanagenesis, and genome reprograming in cancerDisruption of mouse Cenpj, a regulator of centriole biogenesis, phenocopies Seckel syndromeThe human microcephaly protein STIL interacts with CPAP and is required for procentriole formationNovel asymmetrically localizing components of human centrosomes identified by complementary proteomics methodsICK is essential for cell type-specific ciliogenesis and the regulation of ciliary transportCep126 is required for pericentriolar satellite localisation to the centrosome and for primary cilium formationPoc1A and Poc1B act together in human cells to ensure centriole integrityCentriolar association of ALMS1 and likely centrosomal functions of the ALMS motif-containing proteins C10orf90 and KIAA1731The deubiquitinating enzyme CYLD controls apical docking of basal bodies in ciliated epithelial cellsCentrobin-tubulin interaction is required for centriole elongation and stabilityA novel role of human holliday junction resolvase GEN1 in the maintenance of centrosome integrityUbiquitin-proteasome system controls ciliogenesis at the initial step of axoneme extensionRBM14 prevents assembly of centriolar protein complexes and maintains mitotic spindle integrityCombining Cep290 and Mkks ciliopathy alleles in mice rescues sensory defects and restores ciliogenesisThe SCF-FBXW5 E3-ubiquitin ligase is regulated by PLK4 and targets HsSAS-6 to control centrosome duplicationNegative regulation of ciliary length by ciliary male germ cell-associated kinase (Mak) is required for retinal photoreceptor survivalCDK6 associates with the centrosome during mitosis and is mutated in a large Pakistani family with primary microcephalyA missense mutation in DCDC2 causes human recessive deafness DFNB66, likely by interfering with sensory hair cell and supporting cell cilia length regulationThe microtubule affinity regulating kinase MARK4 promotes axoneme extension during early ciliogenesis.Combined NGS approaches identify mutations in the intraflagellar transport gene IFT140 in skeletal ciliopathies with early progressive kidney DiseaseDISC1 regulates primary cilia that display specific dopamine receptorsSperiolin is a novel human and mouse sperm centrosome proteinExome sequencing and analysis of induced pluripotent stem cells identify the cilia-related gene male germ cell-associated kinase (MAK) as a cause of retinitis pigmentosaMicrocephaly with simplified gyration, epilepsy, and infantile diabetes linked to inappropriate apoptosis of neural progenitorsProteomic identification of Hsp70 as a new Plk1 substrate in arsenic trioxide-induced mitotically arrested cellsAutophagy promotes primary ciliogenesis by removing OFD1 from centriolar satellitesmiR-129-3p controls cilia assembly by regulating CP110 and actin dynamicsUnique properties of Drosophila spermatocyte primary ciliaCEP70 protein interacts with γ-tubulin to localize at the centrosome and is critical for mitotic spindle assemblyATR-mediated regulation of nuclear and cellular plasticityCiliogenesis and the DNA damage response: a stressful relationshipHuman basal body basicsCellular Mechanisms of Ciliary Length ControlCurrent topics of functional links between primary cilia and cell cycleGenetic changes shaping the human brainAxonemal positioning and orientation in three-dimensional space for primary cilia: what is known, what is assumed, and what needs clarificationCell cycle progression by the repression of primary cilia formation in proliferating cellsThe role of the cilium in normal and abnormal cell cycles: emphasis on renal cystic pathologiesInterphase centrosome organization by the PLP-Cnn scaffold is required for centrosome functionp53 protects against genome instability following centriole duplication failure
P2860
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P2860
Centrioles, centrosomes, and cilia in health and disease
description
2009 nî lūn-bûn
@nan
2009 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Centrioles, centrosomes, and cilia in health and disease
@ast
Centrioles, centrosomes, and cilia in health and disease
@en
type
label
Centrioles, centrosomes, and cilia in health and disease
@ast
Centrioles, centrosomes, and cilia in health and disease
@en
prefLabel
Centrioles, centrosomes, and cilia in health and disease
@ast
Centrioles, centrosomes, and cilia in health and disease
@en
P3181
P1433
P1476
Centrioles, centrosomes, and cilia in health and disease
@en
P304
P3181
P356
10.1016/J.CELL.2009.10.036
P407
P577
2009-11-13T00:00:00Z