Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome
about
The Role of PARP Inhibitors in the Treatment of Gynecologic MalignanciesCancer and Lhermitte-Duclos disease are common in Cowden syndrome patientsThe lipid phosphatase activity of PTEN is critical for its tumor supressor functionThe tumor-suppressor activity of PTEN is regulated by its carboxyl-terminal regionEvidence for regulation of the PTEN tumor suppressor by a membrane-localized multi-PDZ domain containing scaffold protein MAGI-2Phosphorylation of the PTEN tail regulates protein stability and functionPTEN expression is reduced in a subset of sporadic thyroid carcinomas: evidence that PTEN-growth suppressing activity in thyroid cancer cells mediated by p27kip1Cancer-associated PTEN mutants act in a dominant-negative manner to suppress PTEN protein functionPTPN14 is required for the density-dependent control of YAP1Identification of PTPN23 as a novel regulator of cell invasion in mammary epithelial cells from a loss-of-function screen of the 'PTP-ome'P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphataseAssociation of SET domain and myotubularin-related proteins modulates growth controlSignaling by target of rapamycin proteins in cell growth controlPTEN represses RNA Polymerase I transcription by disrupting the SL1 complexThe PTEN/PI3K pathway governs normal vascular development and tumor angiogenesisGermline PTEN promoter mutations and deletions in Cowden/Bannayan-Riley-Ruvalcaba syndrome result in aberrant PTEN protein and dysregulation of the phosphoinositol-3-kinase/Akt pathwayPTEN as an effector in the signaling of antimigratory G protein-coupled receptorProtean PTEN: form and functionMolecular origins of cancer: Molecular basis of colorectal cancerDe novo germline and postzygotic mutations in AKT3, PIK3R2 and PIK3CA cause a spectrum of related megalencephaly syndromesThe mTOR signalling pathway in human cancerThe PI3K pathway as drug target in human cancerGermline mutations and variants in the succinate dehydrogenase genes in Cowden and Cowden-like syndromesRegulation of G1 progression by the PTEN tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/Akt pathwayHamartomatous polyposis syndromesTargeting the mTOR signaling network for cancer therapyThe Croonian Lecture 1997. The phosphorylation of proteins on tyrosine: its role in cell growth and diseaseGenes other than BRCA1 and BRCA2 involved in breast cancer susceptibilityRetroviral expression of a kinase-defective IGF-I receptor suppresses growth and causes apoptosis of CHO and U87 cells in-vivo.Ductal approaches to assessment and management of women at high risk for developing breast cancerMolecular responses to hypoxia in tumor cellsPTEN deficiency: a role in mammary carcinogenesis.Role of APC and DNA mismatch repair genes in the development of colorectal cancers.Genetic polymorphisms in DPF3 associated with risk of breast cancer and lymph node metastases.Genetic basis of Cowden syndrome and its implications for clinical practice and risk managementThe PTEN tumor suppressor gene and its role in lymphoma pathogenesisAmino acid management in cancerBalancing Proliferation and Connectivity in PTEN-associated Autism Spectrum DisorderSomatic mosaicism in the human genomePTEN: A master regulator of neuronal structure, function, and plasticity
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P2860
Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome
description
1997 nî lūn-bûn
@nan
1997 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Germline mutations of the PTEN ...... st and thyroid cancer syndrome
@ast
Germline mutations of the PTEN ...... st and thyroid cancer syndrome
@en
type
label
Germline mutations of the PTEN ...... st and thyroid cancer syndrome
@ast
Germline mutations of the PTEN ...... st and thyroid cancer syndrome
@en
prefLabel
Germline mutations of the PTEN ...... st and thyroid cancer syndrome
@ast
Germline mutations of the PTEN ...... st and thyroid cancer syndrome
@en
P2093
P2860
P3181
P356
P1433
P1476
Germline mutations of the PTEN ...... st and thyroid cancer syndrome
@en
P2093
Peacocke M
P2860
P2888
P3181
P356
10.1038/NG0597-64
P407
P577
1997-05-01T00:00:00Z
P6179
1006875378